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Biomedical subjects

S Nemec

Publications and source records attributed to S Nemec.

11 recordsLinked to original sources

Antimicrobial activity of naphthoquinones from fusaria.

Twenty-two naphthoquinone compounds isolated or derived synthetically from culture extracts of Fusarium solani and F. oxysporum were examined for antimicrobial activity. Fifteen exhibited antibiotic activity against Staphylococcus aureus, and 12 were active against Streptococcus pyogenes, but none were active at the highest rate of 128 micrograms/ml against Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, Proteus vulgaris, Serratia marcescens, or Pseudomonas aeruginosa. Of 8 plant pathogenic bacteria tested against 11 naphthoquinones, Corynebacterium poinsettiae was inhibited by 6 compounds, and Pseudomonas viridiflava was weakly inhibited by one. Only one of a group of 6 fluorescent soil pseudomonads was inhibited by one naphthoquinone. Antifungal activity of 10 compounds against 8 fungal plant pathogens was limited to inhibition of Phytophthora parasitica by one naphthopyran.

Anti-Bacterial Agents↗

[Diagnostic and therapeutic role of so-called laparosplenectomy in Hodgkin's disease].

Results obtained with laparosplenectomy in the diagnosis and treatment of Hodgkin's disease are reported. The soundness of this method is asserted with regard to establishment of the anatomopathological stage, the improved tolerance of subsequent antiblastic management and the virtual absence of post-operative complications. The long-term progression of the disease, however, cannot be examined, since reliable data are not available. It will the tasks of the haematologists to follow these patients and record the clinical events observed.

Adolescent↗

[Hürthle's tumors of the thyroid: a clinical case and review of the literature].

Hürthle tumors of the thyroid gland are uncommon lesions, histologically related to the well differentiated types of thyroid malignancies. Lesions predominantly composed of Hürthle cells are difficult for pathologists to be diagnosed and, consequently, for surgeons to be properly treated. In this report a case of Hürthle cell carcinoma was firstly treated with hemithyroidectomy plus isthmectomy; once frozen section examination revealed signs of malignancy a total thyroidectomy was performed.

Adenoma↗