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Biomedical subjects

S Nawano

Publications and source records attributed to S Nawano.

At least 37 records · Page 2Linked to original sources

Early hepatocellular carcinoma: MR imaging.

All areas in hepatic lesions designated as adenomatous hyperplasia (AH) with malignant foci have recently been recognized as cancer. AH with malignant foci can be classified into two types, depending on the presence of overt cancerous nodules. Lesions without macroscopic nodules are defined as early hepatocellular carcinoma (HCC), while those with a macroscopic component are defined as HCC with early components. A comparative study of early HCC and HCC with early components was performed with magnetic resonance imaging. Early HCC lesions (n = 20) were isointense (n = 11) and hyperintense (n = 9) on T1-weighted spin-echo images and isointense (n = 17), partially hyperintense (n = 2), or hypointense (n = 1) on T2-weighted spin-echo images relative to the surrounding liver. Lesions classified as HCC with early components (n = 8) were hyperintense (n = 5), isointense (n = 2), and of mixed signal intensity (n = 1) on T2-weighted images. T1-weighted imaging was superior to T2-weighted imaging in depicting early HCC, but the latter could be useful in evaluating the progression of HCC in the histopathologically early stages.

Carcinoma, Hepatocellular↗

[A comparative study of histopathological findings of resectable pancreatic carcinoma (t1, t2 cases) with ERCP and CT images].

The diagnosis of pancreatic carcinoma at early stage has been considered very difficult. Histopathological findings of resectable pancreatic carcinoma less than 4 cm in size (t1, t2 cases) have been compared with endoscopic retrograde cholangiopancreatography (ERCP) and computed tomography (CT) images for the purpose of improving the diagnosis of pancreatic carcinoma. Twenty-six patients with pancreatic carcinoma less than 4 cm in size, who underwent surgery at the National Cancer Center Hospital from January 1980 to December 1988, were analyzed. The mean age of these 26 cases was 64 years (range of 45 to 78 years), with 13 males and 13 females. Pancreatograms were classified into 4 groups such as stenosis, tapering, obstruction and others, and this classification was compared with histopathological findings. However, ERCP classification showed no correlation with histopathological findings. CT images of the margins, characteristics and density of the tumor were compared with histopathological findings. There existed a good correlation between CT images and histopathological findings such as histological differentiation, macroscopic type of cut surface and INF. For an accurate diagnosis of pancreatic carcinoma, it is important that localization of the tumor is diagnosed first by ERCP and the characteristics of the tumor should be recognized by CT images.

Adenocarcinoma↗

[A study of image processing in CR mammography; gradation processing].

CR image is made by several kinds of image processing. Gradation processing is most important to make images among them and its type can be decided by the kinds of x-ray examinations. 1.2 G gradation processing is generally recommended for CR-mammography by the CR maker, but it has not been fully studied that whether 1.2G was the ideal one or not to image masses and/or calcifications. So, we compared the image obtained by 1.2G gradation processing with one by 1.0 d gradation processing that we made about imaging sensitivity of them in 18 cases with breast cancer. 15 out of 18 cases had good mass images and all of 6 cases showed good calcified images in the latter condition due to its high declination ( = gamma). So, we have concluded that 1.0 d gradation processing was better than 1.2G in CR-mammography.

Breast Neoplasms↗

Synchronous early gastric cancer.

Synchronous early gastric cancer (EGC) has a prevalence of approximately 9%. The barium study findings of 73 patients with 163 synchronous EGC tumors were retrospectively reviewed, and the size, location, and morphologic type of each lesion considered malignant were analyzed and correlated with the endoscopic and final pathologic findings. Barium studies and endoscopy each correctly demonstrated 116 of the 163 synchronous EGC lesions. Those lesions not demonstrated by either technique were small, shallow, or flat and confined to the mucosa. Our results indicate that a careful preoperative evaluation with radiography and endoscopy currently can depict about 70% of these lesions.

Barium Sulfate↗

CNS changes in Usher's syndrome with mental disorder: CT, MRI and PET findings.

CNS changes in a case of Usher's syndrome associated with schizophrenia-like mental disorder were observed by CT, MRI and PET. The neuro-radiological findings of the case demonstrate the degenerative and metabolic alterations in various regions of cortex, white matter and subcortical areas in the brain. Mental disorder of the case is almost indistinguishable from that of schizophrenia, but the psychotic feature is regarded as an atypical or mixed organic brain syndrome according to the classification in the third edition of the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (DSM-III).

Adult↗

Imaging diagnosis of von Hippel-Lindau disease: a case report.

A patient with typical manifestations of von Hippel-Lindau disease is presented. In this 44 year-old man, cerebellar hemangioblastoma was found initially and he was operated upon at the age of 25. This was followed by retinal angiomas treated by cryocoagulation and, recently, by paresthesia of both legs and frequent shooting pains over the lower abdomen. A computed tomography disclosed multiple small cysts of the pancreas, bilateral multicentric renal carcinomas and a spinal angioma in the lumbar portion, confirmed by magnetic resonance imaging, and consistent with neurogenic manifestations. Multiple enucleations of the renal cell carcinomas were carried out, most of which were histologically well differentiated adenocarcinomas. There was no family cluster. Six months postoperative, the patient is doing well.

Adult↗