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Biomedical subjects

S Naidoo

Publications and source records attributed to S Naidoo.

72 records · Page 4Linked to original sources
PubMed1993

Effectiveness of an electric toothbrush on plaque removal in periodontal patients.

A blind, two-way crossover clinical trial was carried out to compare the effectiveness of plaque removal between an electric toothbrush (Interplak) and a conventional manual toothbrush (Butler 311). Twenty adult patients having completed all active periodontal therapy and currently on periodontal maintenance program participated in the study. Each toothbrush was used for a period of 2 weeks by all subjects. The mean differences between baseline plaque scores and after the subjects used the brushes were analyzed by the paired t-test. The results indicated no difference in plaque removal between the Interplak and the control brush with the exception of the distal surfaces of the maxillary teeth.

Adult↗
PubMed1990

Personal constructs of fluency: a study comparing stutterers and nonstutterers.

The personal construct systems relating to fluency of a group of five stutterers and a group of five nonstutterers were examined using the repertory grid technique. The results support findings that stereotypical notions about stuttering were characteristic of both stutterers and nonstutterers and did not support Fransella's 1972 assumption that constructs relating to fluency differ in the communication subsystems of stutterers and nonstutterers.

Adult↗
PubMed1988

Epidemiological considerations of the present status and future growth of the acquired immunodeficiency syndrome epidemic in South Africa.

Limited epidemiological data on acquired immunodeficiency syndrome (AIDS) and human immunodeficiency virus (HIV) infection have been assembled by voluntarily reported AIDS figures, blood donor serum prevalence and high-risk sentinel population and random background population sero-prevalence studies. The HIV epidemic in South Africa can thus be shown to consist of four separate epidemics of which the heterosexual epidemic will undoubtedly constitute the major growth in this country. Intervention must be directed to shrinking the promiscuous core which sustains this epidemic by directing attention at female prostitution and limiting the reproductive rate of the epidemic by energetic and professionally directed education at an early stage of a child's school career. Sexually transmitted diseases will play a major role in the determination of the extent of the heterosexual epidemic.

Acquired Immunodeficiency Syndrome↗
PubMed1979

Effects of age on the metabolism of thyroid hormones by rat brain tissue in vitro.

Using a newly-devised chromatographic method for the separation of the acetic and propionic analogues of triiodothyronine (T3) and thyroxine (T4), we studied the metabolism of radioactively labeled T3 and T4 in rat brain homogenates to determine whether the rates of metabolism and the types of products formed are influenced by the age of the animal. The separation of metabolites is achieved on silica gel H in a solvent system consisting of methylacetate-2.5% ammonia (W/V) (95:5 V/V). Results clearly demonstrate that the metabolism of both T3 and T4 is age-dependent. Metabolism of T3 occurred at a significant rate during the early postnatal period (11 and 23 days), declined sharply between 23 and 40 days and was almost completely absent in the adult brain (100 days). Free iodide was the only product that could be identified in extracts of the reaction mixture. Neither the acetic nor propionic acid analogues of T3 were present in significant amounts. In the case of T4, iodide was the major metabolite formed. In addition, a significant amount of triiodothyroacetic acid was present in extracts of homogenates from the 11- and 23-day-old rats but not in those from older animals. Although initially, the rate of T4 metabolism was greater in the younger animals, over a 6-hour period, the amount metabolized was approximately the same at all ages studied. We conclude that these age-dependent changes in the metabolism of T3 and T4 may influence T3 receptor interactions in brain tissue and thereby regulate hormonal activity at the cellular level during the critical period of brain development.

Aging↗
PubMed1975

Comparison of trimethoprim-sulfamethoxazole with sulfamethoxazole in urinary tract infections of children.

The effect of trimethorpim-sulfamethoxazole was compared with that of sulfamethoxazole alone in 26 children with urinary tract infection, randomly assigned according to a double-blind procedure to two equally sized groups. TMX-SMX was found to be superior in rendering the urine culture negative for the 3 months after the start of treatment. Also, over 12-month follow-up period there were fewer recurrences in the patients who received TMP-SMX but here the difference between the two groups did not reach statistical significance.

Administration, Oral↗
PubMedDate not supplied

One year surveillance of HIV-1 infection in Johannesburg, South Africa.

A sero-epidemiological surveillance study to monitor the prevalence of HIV-1 infection in Johannesburg, South Africa, was commenced in February 1988. The population selected for study were attenders at clinics for sexually transmitted diseases (STD) and at family planning (FP) clinics. In the 12 months of the study 6631 sera were tested. Of the STD attenders, 15 of 1224 black females (1.2%) and 21 of 2482 black males (0.8%) were positive. Of the 449 white males tested 49 were homosexual, amongst whom 10 (20.4%) were positive; in the heterosexual white male group 4 of 400 (1.0%) were positive. Of the FP clinic attenders, 4 of 1459 black females (0.3%) were positive. 68 of the 6631 sera tested were indeterminate for infection. No attenders were positive for HIV-2 infection. These data confirmed the entry of HIV infection into the black population in South Africa.

Ambulatory Care Facilities↗