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Biomedical subjects

S NIEWIAROWSKI

Publications and source records attributed to S NIEWIAROWSKI.

At least 19 recordsLinked to original sources

Blood clotting factors in cerebrospinal fluid.

The activity of blood clotting factors has been investigated in cerebrospinal fluid. No cephalin-like activity was found in cerebrospinal fluid but prothrombin activity averaged about 0.5% of normal plasma activity. The activity of factor VII was negligible in almost all cases. The activity of antihaemophilic factors showed great variation but in the majority of cases it did not exceed 1% of normal plasma activity. High activity for factor V was found in almost all samples of cerebrospinal fluid.

Blood Coagulation↗

The antithrombin activity of glucuronic esters of bilirubin.

The plasma of patients with pronounced jaundice as well as that of cats with experimental obstructive jaundice inhibits the clotting of normal plasma with thrombin. The influence of different bile constituents-bilirubin, bilirubin glucuronides, sodium salts of bile acid-on the clotting of plasma or fibrinogen with thrombin was examined. Bilirubin glucuronides in concentrations above 8 mg.% showed antithrombic activity but other substances were inactive. Glucuronic acid and phenolphthalein glucuronide in concentrations up to 100 mg.% did not have any influence on the thrombin time.

Animals↗