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Biomedical subjects

S N Tandon

Publications and source records attributed to S N Tandon.

40 records · Page 3Linked to original sources

Description of shapes in CT images. The usefulness of time-series modeling techniques for identifying organs.

An attempt has been made to investigate the usefulness of AR and CAR modeling techniques for shape description of substructures in CT images. The efficacy of the models have been checked using two organ shapes (liver and kidney) obtained from abdominal CT sections at nearly identical locations. The contours of the substructures representing the shapes, along with the sequence of coordinates, have been obtained by using edge detection followed by an edge-linking technique, where maximum and minimum lengths of the edge segments could be varied. The modeling techniques thus applied have resulted in feature vectors of the organ shapes corresponding to these models. Validity of the models has been assessed on the basis of lower values and consistency of Euclidean distances within a class, as well as the differences of these values with other classes.

Humans↗

Serum protein profile in normal pregnancy and in relation to parity.

Forty pregnant females of third trimester and their twenty non-pregnant controls were screened for Hb%, PCV and serum protein differentials in relation to parity. Paper electrophoresis method revealed significant rise in mean levels of serum alpha 1, alpha 2 and beta-globulins in pregnant females as compared to non-pregnant controls, which may be due to the rise in pregnancy-associated-proteins. Radial immunodiffusion method revealed rise in mean serum IgM level with increasing parity, whereas a decrease in mean serum IgG level was observed which might be due to the placental membrane-transfer and/or decreased IgG synthesis. Haematological investigations revealed decreased Hb% and PCV which may have been caused both due to increased demand of nutrients as well as by haemodilution, associated with water retention during pregnancy.

Adult↗

Role of vagus in thermal panting.

In dogs anaesthetised with pentobarbitone sodium, raising the body temperature from 37 degrees C to 42 degrees C increased the rate of respiration and pulmonary ventilation but decreased the tidal volume. A similar change though of a lower magnitude, was observed in these parameters after cold blocking the vagi. At 40 degrees C body temperature, however, the vagal block was not effective in reducing the rate. The significance of hyperthermic panting mechanism dominating the Hering-Breuer mechanism at 40 degrees C has been discussed. It has been postulated that the vagi carry temperature dependent afferents that have effect opposite to the Hering-Breuer reflex. At 42 degrees C when respiratory failure usually sets in the temperature regulating function of respiration is the last to be lost.

Animals↗