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Biomedical subjects

S Muraki

Publications and source records attributed to S Muraki.

48 records · Page 3Linked to original sources

Relationship between heart rate and oxygen uptake during submaximal arm cranking in paraplegics and quadriplegics.

The purpose of this study was to clarify the effect of the level of spinal cord injury (SCI) and of daily exercise on the relationship between heart rate (HR) and oxygen uptake (VO2) in persons with SCI (PSCI) during an arm cranking exercise. Eighteen PSCI were divided into three groups according to the level of SCI; 4 quadriplegics (C6-C8), 7 high- level paraplegics (T3-T8), and 7 low-level paraplegics (T10-L2). In the relationship between HR and VO2, the higher the level of SCI, the smaller the slope of regression line, that means the HR at a given VO2 become larger as level of SCI was higher. Significant differences were found among these regression lines (P < 0.01). In addition, the regression lines between HR and VO2 in active persons tended to shift toward upper in comparison with those in inactive persons. The present investigation clearly shows that the HR-VO2 relationship in PSCI is remarkably influenced by the level SCI and physical training.

Adult↗

Characteristics of the health conditions of old patients with spinal cord injury.

The state of health of old patients with spinal cord injury (SCI) was investigated to clarify the disorders that they are presently suffering from. A questionnaire was sent by mail to 668 patients with SCI living in western Japan. Valid answers were returned from 448 (67%), and they were divided into a young group (160 patients aged 18-39 years), middle-aged group (193 patients aged 40-59 years), and elderly group (95 patients aged 60-73). About 30% in the young group answered that they were ill or worrying about their health. This percentage was about 60% in the middle-aged and elderly groups. According to disease types, none of the young group had urological diseases except urological impairment or cardiovascular diseases, but many of the elderly group had urological tract infection, kidney diseases, cardiovascular diseases, and digestive diseases. Decubitus ulcer was reported in all groups. Urological diseases and decubitus ulcer were considered to be characteristic ailments of individuals with SCI. The elderly group was also characterized by a high incidence of adult diseases such as hypertension and diabetes mellitus. Therefore, the types of diseases and their frequency are considered to be different in older patients with SCI compared with the aged population in general because of the characteristic conditions of SCI in addition to adult diseases.

Adolescent↗

Usefulness of a simple device to measure aural canal temperature.

In patients with spinal cord injury, rectal temperature is difficult to use as body temperature due to impairment such as defecation disturbance. We developed an earphone type device to measure aural canal temperature that can be also used during exercise in patients with spinal cord injury and evaluated its usefulness. The subjects consisted of 11 healthy male students. They exercised for 30 minutes using an ergometer until the heart rate increased to 150-160 bpm. Aural canal temperature, rectal temperature, and non-contact tympanic membrane temperature were measured before, during, and after exercise. This device for the measurement of aural canal temperature was produced by cutting the tip of a commercially available earphone and connecting a thermocouple wire to it. This device is very small and causes no discomfort even during long wearing or inconvenience during exercise. The aural canal temperature obtained in this study was very stable compared with the rectal temperature or non-contact tympanic membrane temperature and thus may be useful for monitoring body temperature.

Adolescent↗

Gender difference in the relationship between physical fitness and mental health.

The purpose of this study was to examine the relationship between physical fitness and mental health in men and women. Twenty-five students (12 men and 13 women) aged 19 to 23 years participated in this study as subjects with low life stress who did not participate in competitive sports. Their physical fitness level was determined according to VO2max test results obtained using a cycle ergometer, and their mental health status according to the results of psychological measurement using the Profile of Mood States (POMS) and Spielberger's State-Trait Anxiety Inventory (STAI). In the men, there was significant correlation of VO2max with each of the POMS subscores for tension (r = -0.61), depression (r = -0.61), fatigue (r = -0.60), and total mood disturbance (r = -0.59), as well as with STAI state (r = -0.66) and trait (r = -0.76) anxiety scores. On the other hand, no similar correlation was found in the women. These results suggest that the relationship between physical fitness and mental health in men differs from that in women.

Adult↗

[Cerebrospinal fluid fistula following an operation of mediastinal schwannoma: a case report].

A 33-year-old man was operated for the mediastinal schwannoma. During the operation, the 9 th intercostal nerve was avulsed and revealed liquorrhea. Lyodura and fibrin glue was applied for sealing the site of dural defect. But post-operative course was not successful. So, we used the external cerebrospinal fluid drainage system. After this procedure, thoracic fluid from the chest tube was reduced and we could remove the chest tube in the 20th post operative day. This case indicates that in case of thoracotomy, it is difficult to expect easy closure of cerebrospinal fluid fistula under conservative therapy. Therefore it was considered that specific repair during the operation and spinal drainage in the post-operative early phase should be performed.

Adult↗

[Effects of lidocaine upon CCK-PZ and secretin producing paraneurons in the canine duodenum responding to luminal chemical stimuli (author's transl)].

Amino acid solution (50 mM tryptophan and 50 mM phenylalanine in saline) introduced into the canine duodenal loop causes an increased enzyme output from the pancreas, whereas administration of 0.1 N HCl into the duodenal loop causes an increased juice flow from the organ. Local anesthetic, lidocaine, introduced into the duodenal lumen suppressed the pancreatic enzyme releasing response to the intraluminal amino acid without affecting the juice flow response to the hydrochloric stimulus. Intravenously administered lidocaine did not block the pancreatic response to the intraluminal amino acid stimulus, suggesting that lidocaine affects the chemoreceptive, apical part of the endocrine cell or paraneuron which releases cholecystokinin-pancreozymin (CCK-PZ). Neither was the pancreas responding to an intravenous injection of CCK-PZ (5 Ivy Dog Units) suppressed by intravenously administered lidocaine even when its arterial concentration exceeded the convulsion level. This indicates that lidocaine affects the duodenal paraneurons recognizing the luminal stimuli but not the pancreatic cells responding to the hormones released by them. The results further suggest that in paraneurons as well as in neurons there seems to be a spectrum with regard to the susceptibility to anesthetics; thus the secretin releasing paraneuron is much more resistant to lidocaine than the CCK-PZ producing one.

Amino Acids↗

Age-related pattern of body density and body composition in Japanese males and females, 11 and 18 years of age.

The age-related pattern of body density and body composition in Japanese males (n = 266) and females (n = 318), 11.00 to 18.99 years of age was studied. Body density (BD) as well as height, body weight, and seven skinfold thicknesses were measured. Percentage fat (%Fat) was calculated using the age- and sex-specific equation of Lohman. Fat mass (FM), fat-free mass (FFM), and the body mass index (BMI) were calculated. The trend for BD in males was lowest at 11 years (1.0530 g/ml) and increased to 1.0695 g/ml at 14 years, and then decreased slightly at 15 to 17 years. In female, BD decreased from 1.0530 g/ml at 13 years to 1.0424 g/ml at 17 years. Mean %Fat was highest in males at 11 years (15.8%), and lowest at 14 years (10.1%). The highest mean %Fat in females occurred at 16 years (22.8%), and the lowest at age 11 years (15.2%). Overall, only 6.8% of males and 3.1% of females were classified as obese. Between 11 and 18 years, FFM of males differed by 20.7 kg or 67.9%, whereas females showed a difference of only 10.8 kg or 34.7%. Consequently, age effects explained approximately 60% of the male variance of FFM but only 26% in females. Body density of each sex and age group in this study did not differ significantly from previous Japanese studies, and the pooled BD data for 1,457 Japanese including the present study are reported as a reference.

Adolescent↗

Age-related pattern of body density and body composition of Japanese men and women 18-59 years of age.

Age-related patterns of body size and composition were studied in a cross-sectional sample of Japanese adults 18-59 years of age. Height, weight, the body mass index (BMI), body density (BD), percentage body fat (%Fat), fat mass (FM), fat-free mass (FFM), and the sum of seven skinfold thicknesses (SF) of 288 men and 552 women were considered. Body density was measured by underwater weighing densitometry. Mean values of height, weight, BMI, BD, %Fat, FM, FFM, and SF of males were 169.0 cm, 65.3 kg, 22.8 kg/m(2), 1.0600 g/ml, 17.0%, 11.4 kg, 53.9 kg, and 95.0 mm, respectively, while corresponding values for females were 157.4 cm, 52.9 kg, 21.4 kg/m(2), 1.0420 g/ml, 24.4%, 13.1 kg, 39.7 kg, and 128.2 mm, respectively. Height, BD, and FFM correlated negatively with age in both sexes, while weight, BMI, %Fat, FM, and SF correlated positively with age. The highest BD and the lowest %Fat were observed in males ages 20 to <25 years (G20) and in females 25 to <30 years (G25). The lowest BD and highest %Fat were observed in G50 in both sexes. Correlations among parameters of body size and composition were stable with age in each sex. Height correlated negatively with BMI and %Fat in females, but not in males. In males, FM started to increase between G20 and G25 and continued to increase until G50, while SF and BMI remained stable during this period. In females, FM accumulation started around 30 years of age and continued until G50 and was accompanied by increases in SF and BMI.

Adolescent↗