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Biomedical subjects

S Murakami

Publications and source records attributed to S Murakami.

At least 883 records · Page 49Linked to original sources
PubMed1979

[Neural mechanisms of group I fibers of neck muscles (author's transl)].

Afferent projection of upper cervical dorsal roots C2 and C3 upon spinal cord and brain stem was investigated on cats using both histological and electrophysiological methods. 1. Degenerated terminals, stained by Fink-Heimer's methods, were found in Rexed's laminae III and IV, intermediate nucleus and ventral horn of the spinal cord and nucleus cuneatus and spinal trigeminal nucleus. 2. Monosynaptic reflex responses were obtained from motor nerves innervating dorsal neck muscles by stimulating the dorsal roots in some decerebrated cats. However, this reflex responses could be unable to elicite in the spinal preparation. 3. The neurons responding exclusively to the ventral rami located in cranial parts of the nucleus and those responding to dorsal rami located in the caudal region. Neurons responding to both rami were also found.

Animals↗
PubMed1978

Sympathetic influence on alveolar surface activity in hyperventilated dog.

Hyperventilating IPPB, defined as intermittent positive-pressure breathing with a frequency of 32 beats/min and inspiratory pressure of 30 cmH2O, was administered for 14 h to open-chested anesthetized dogs in which nerves to one bronchus were operatively blocked. In the nerve-intact lungs, the lung stability index calculated from the pressure-volume relationship decreased with the duration of the hyperventilating IPPB (correlation coefficient r = -0.66, P less than 0.001), and atelectasis and hemorrhage appeared. In the nerve-blocked lungs, the index did not decrease during the 14 h of hyperventilating IPPB, and the appearance was almost normal. After pharmacologic sympathetic block with phenoxybenzamine, the lung stability index of both the operatively nerve-blocked lung and the nerve-intact lung was not decreased by hyperventilating IPPB. From these findings, we conclude that sympathetic block can protect pulmonary surface activity from the adverse effects of hyperventilating IPPB.

Animals↗