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Biomedical subjects

S Mozes

Publications and source records attributed to S Mozes.

46 records · Page 3Linked to original sources
PubMed1980

[The development of the regulation of food intake during ontogenesis--the effect of hyperalimentation on body weight gain in suckling rats].

In an experiment, the number of young rats per nest was reduced to two in time intervals from the 1st to the 6th, from the 6th to the 11th, from the 11th to the 16th, and from the 16th to the 21st day after birth (groups P1, P2, P3 and P4 respectively). The plenty of milk available to the young for a period of five days positively influenced the body weight of the rats in group P2, whereas in the remaining groups the total weight showed no significant change in comparison with normally fed animals. The subsequent normalization of nutrition in the test young (the number of the young in nests was increased to eight) induced a decrease in weight gains in the older test animals (groups P3, P4), whereas in the 6- to 11-day-old rats (P2) the higher weight gains were retained in the next growth stages. The results give evidence that an external interference in the nutrition of rats (hyperalimentation) in the period from the 6th to the 11th day of life can influence, for a longer time, feeding behaviour and weight gains. The relative stability of the body weight of the young after the 11th day of life suggests to the functional involvement of the regulatory mechanisms controlling feed intake in this period of life.

Animal Population Groups↗
PubMed1978

Insulin tolerance in rats.

Insulin tolerance was studied in young (8- to 10-week-old) Wistar rats: a) after the administration of mounting doses of long-acting insulin (10, 40, 160 and 320 units/kg bw.) to animals fed ad libitum on two different diets); b) after the administration of long-acting insulin (1 and 5 units/kg b.w.) to animals which had fasted for different lengths of time. In rats fed ad libitum on the two diets, graded doses of insulin induced (except for the smallest dose) hypoglycaemia of roughly the same intensity, but varying in duration in correlation to the dose. The administration of insulin to fasting rats showed differences in insulin tolerance which were correlated to the duration of the fast. A significant decrease in insulin tolerance was already found after 6 hours. During the given testing period (72 hours), the lowest insulin tolerance was found after a 12 hours' fast and the highest after 48 hours. Insulin tolerance after 24 and 72 hours' fasting was approximately the same; it was higher than after 12 hours, but lower than after 48 hours. The initial blood sugar level (before administering insulin) was not in any way correlated to insulin tolerance determined at various intervals during fasting.

Animals↗
PubMed1978

[Weight increase following administration of insulin to rats with reduced feed intake].

Young male Wistar rats, adapted to single daily administration of feed (from 8.00 to 10.00 a.m.) were studied for the intake of feed, weight gains, and feed consumption per weight gain unit after administration of Superdep insulin in the dose of 10 u kg-1 of body weight. The time limitation of access to food reduced the over-all intake of feed and weight gains and adversely affected the utilization of feed, expressed as consumption per 1 g of weight gain. The administration of insulin partly compensated the adverse effect of the reduced feed intake; this was manifested by better utilization of feeds by the experimental group, in comparison with the control animals.

Animal Nutritional Physiological Phenomena↗
PubMed1977

Hypoglycaemia and food intake in rats given graduated doses of insulin.

Hypoglycaemia of varying duration was induced with graduated doses of long-acting insulin (10, 40 and 160 U/kg b.w.) in young, growing (8- to 10-week-old) male Wistar rats fed ad libitum on two different diets. In all, 6 doses of insulin were administered, at 48-hour intervals. The blood glucose level and food consumption were determined 3, 6, 12, 24 and 48 hours after injecting the insulin. Both the hypoglycaemic effect and elevated food intake during hypoglycaemia depended on the dose of insulin and not on the type of diet. Total food consumption during the experiment (12 days) was markedly raised only in the groups given the maximum dose of insulin (160 U/kg b.w.). The weight gain in all the experimental groups was lower than in the control groups and food consumption per weight gain unit was higher.

Animals↗
PubMed1977

[Weight gains in rats of different ages after administration of insulin].

An experiment was made to examine the body weight gains after administration of deposit insulin (40 units per kg of live weight) in rats at the age of 1-12 days, 8-10 weeks and 18-20 weeks. The administration of insulin to suckling young (aged 11-12 days) did not influence the weight gains. Eight- to ten-week old rats showed a reduction and 18- to 20-week old rats showed a reduction and 18- to 20-week old rats an increase of weight gains in the course of the experiment.

Age Factors↗