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Biomedical subjects

S Moran

Publications and source records attributed to S Moran.

5 recordsLinked to original sources
PubMed1979

Bloodless cardiac surgery utilizing a new low-prime oxygenator.

One hundred consecutive patients undergoing open-heart surgery were subjected to a prospective protocol designed for reduction of homologous blood utilization. The main points of this protocol were careful surgical hemostasis, normovolemic hemodilution, and retransfusion of blood lost to the operating field. It included use of the new Bentley BOS-10 Spiraflo oxygenator (Bentley Laboratories, Inc., Irvine, California, U.S.A.). The patients' ages ranged from 6 to 68 years and their weights from 18 to 84 kg. Fifty-four patients were subjected to valvular surgery, 30 to coronary revascularization, 13 to congenital defects repair, and 3 to resection of atrial myxomas. All patients could be weaned from bypass without receiving any blood. Eighty patients completed their surgery, and 60 were discharged from the intensive care unit without receiving any homologous blood or its derivatives. Total blood usage for the series throughout the entire stay in hospital was 1.32 units/patient, which included six reoperations for excessive bleeding. This reduction in blood utilization was achieved without excessive hemodilution and did not produce significant complications.

Adolescent↗
PubMed1977

[Coronary occlusions associated with chronic arsenic poisoning. Apropos of 2 operated cases].

Examination was made of the clinical history, the results of laboratory tests, of coronary arteriography, and of a histological study of the coronary arterial walls in two young men who had a myocardial infarction. The two men lived in a district where the drinking water had a very high level of arsenic (0.8 parts per million). Neither of the patients presented the risk factors which are usually associated with coronary arteriosclerosis. Neither of the patients presented the risk factors which are usually associated with coronary arteriosclerosis. A histological study of the pathological left ventricular wall, which was removed at operation, showed very characteristic features of fibrous thickening of the intima, with preservation of the internal elastic lamina, of the medial and of the adventitia. Such an arterial abnormality may effect the larger coronary arteries just as well as the medium and small ones. Clinical presentation of this condition is often in young subjects.

Adult↗
PubMed1975

Mood, primary heroin withdrawal, and acute methadone administration.

This study was designed to: describe the internal state of addicts undergoing primary withdrawal, determine how the internal state is altered by the alleviation of withdrawal stress through an acute dose of methadone, and to determine a predictor of the probability of a patient completing detoxification. Sixty-seven male and female heroin addicts accepted for methadone detoxification were administered a 65-item Profile of Mood States (POMS). Forty-nine of the Ss were tested immediately prior to receiving their initial dose of methadone and again 45 minutes later, while the remaining 18 Ss were only tested 45 minutes after receiving their methadone in order to control for the effects of repeated testing. Each of the subscales measured by the POMS showed a significant decrease in mood disturbance following methadone administration (p less than .0001); these differences could not be attributed to the effects of repeated testing. Factor analysis of pre- and post-methadone treatment scores indicated a two-factor structure prior to receiving methadone and a single unified mood state after the alleviation of primary withdrawal stress. The Anger subscale, administered immediately prior to receiving methadone, was a highly significant predictor of the completion of detoxification (p less than .005). Further implications of the results were discussed.

Adolescent↗