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Biomedical subjects

S Montgomery

Publications and source records attributed to S Montgomery.

At least 73 records · Page 4Linked to original sources

Leukotrienes: inflammatory mediators--a review.

This article reviews a group of inflammatory mediators called leukotrienes. It includes their historical background, chemical pathway of formation, presence in cells and fluids, and biologic activity. These potent substances may be involved in pulpal and periradicular disease, but such involvement has not yet been reported.

Arachidonic Acid↗

Misrepresentation of stimulant street drugs: a decade of experience in an analysis program.

The findings of the Los Angeles County Street Drug Identification Program over the period from 1971 to 1980 for analysis of 1163 samples of street drugs represented as stimulants are presented. Of the 614 alleged cocaine samples, cocaine was found to be absent in 19.2%, found combined with stimulant substitutes in 22.5%, and found by itself in 58.3% of these samples. The validity for 473 alleged amphetamine samples was only 27.1%, with 23.0% of samples found to contain stimulant substitutes along with amphetamine, and 49.9% of the samples lacking any of the alleged drug. Seventy-six alleged methamphetamine samples showed 32.9% validity, with 3.9% of samples having mixtures of alleged drug and substitutes, and 63.2% of samples lacking any methamphetamine. A total of 15 different stimulant substitutes were found in 74 combinations. Caffeine, ephedrine, lidocaine, and procaine were the commonest substitutes.

Adult↗

Endodontics. Diagnostic, treatment planning, and prognostic considerations.

An efficient systematic approach to proper diagnosis of pulpal and periradicular disease is presented. Then treatment planning considerations that determine if a tooth can be endodontically treated, if it has strategic value to be treated, and if the patient really wants the treatment are discussed. The long-term success rate of endodontic treatment is also discussed along with the predictability of emergency treatment for the patient being treated for urgent care.

Acute Disease↗

Early unwanted effects of fluphenazine esters related to plasma fluphenazine concentrations in schizophrenic patients.

Seven outpatients already receiving neuroleptic drugs by depot intramuscular injections were treated in two consecutive 3-week periods with 25 mg fluphenazine doses as enanthate and decanoate esters in a double-blind crossover study. They were assessed for incidence of akinesia, involuntary movement, autonomic disturbances and drowsiness, using a rating scale, and their blood pressures and pulse rates were recorded. Blood was collected for plasma fluphenazine and plasma prolactin assay. Additionally, a handwriting test was applied. A higher incidence of unwanted drug effects occurred when plasma fluphenazine concentrations were maximal, but this was not so with prolactin concentrations. No significant blood pressure changes occurred. Small increases in pulse rate and decreases in handwriting length occurred, but these changes were not associated with high fluphenazine levels.

Adult↗

Use of xeroradiography for length determination in endodontics.

Files inserted and secured in forty-seven canals of maxillary and mandibular cadaver jaw sections were radiographed by conventional and xeroradiographic means, with the use of positioning devices and beam-guiding instruments. Measurements of the radiographically interpreted distance and the actual distance of files from the anatomic apex were made and compared. The data were analyzed by use of the Student's t test. There was no statistically significant difference between conventional and xeroradiographic methods. Xeroradiographs were subjectively judged better than conventional radiographs for maximum visualization of dental structures important to endodontics. Radiation levels needed for quality radiographs were found to be less with the xeroradiographic process.

Cadaver↗

External cervical resorption after bleaching a pulpless tooth.

A tooth with cervical resorption possibly caused by an internal bleaching technique was treated with calcium hydroxide. This case had characteristics in common with the other seven cases that have been described in the literature. Several possible treatment methods are discussed, along with the speculation that internal bleaching of tetracycline-discolored teeth may lead to cervical resorption.

Adult↗