Search PubMed⌕ Search

Biomedical subjects

S Mitra

Publications and source records attributed to S Mitra.

At least 361 records · Page 20Linked to original sources

More on Nei and Roychoudhury's sampling variances of heterozygosity and genetic distance.

The inequality relationship between the expected values of (j(x)-g)2 and (ĝ-g)2, where j(x) is a biased and ĝ is an unbiased estimate of population homozygosity g, were examined earlier by Nei and Roychoudhury (1974) and later by Mitra (1975). The improvement in the inequality still left much to be desired. In this paper a lower boundary of g has been obtained which may be regarded as ultimate for ensuring a smaller expected value of (j(x)-g)2 than the corresponding value of (ĝ-g)2.

Genetics, Population↗

Effect of adjustment for sex composition in the measurement of fertility on intrinsic rates.

The inconsistencies inherent in the one-sex models created a need for the construction of what are known as marriage functions, especially for the measurement of fertility. But attempts to develop marriage functions have been frustrated by the inability of the proposed functions to meet certain consistency conditions and also by difficulties in empiracally determining function parameters. Among several functions proposed so far, Das Gupta's (1972) "effective population" deserves special mention. He uses both sexes in its formulation, and has shown that the constancy of fertility rates based on such a function together with the constancy of survivorship probabilities of both sexes would result in a stable population. It is suggested in this article that the major source of the problem in a two-sex model seems to be the requirement that the model has to be specific both for sex and age. The ideal of incorporating the relative composition of one sex in the age-specific rates of the other, thereby creating a function dependent on both sexes, is advanced in this article. Such functions, defined explicitly for births, can be easily translated into age-specific birth rates. In addition to simplicity in the definition and form, the conditions leading toward stability can also be established. Interestingly enough, the intrinsic rate for this two-sex model lies in the interval determined by the rates obtained from the two one-sex models.

Birth Rate↗

Influence of instantaneous fertility decline to replacement level on population growth: an alternative model.

If age-specific birth rate mx of a stable population drop abruptly to mx/Ro, where Ro is the net reproduction rate, then, according to Keyfitz, the size of the ultimate stationary population relative to that at the beginning of the process is given by I = beoo(Ro - 1)/(rmuRo), where b and r are the birth rate and the rate of growth, respectively, of the stable population, eoo the life expectancy at birth, and mu the average age at childbirth in resulting stationary population. Noting that the decline in mx need not necessarily be uniform, investigation has veen carried out to examine the effect on I when fertility decline is more rapid at higher ages. In particular, the effect of the reduced age-specific rates such as mxe-rx (which also produces a stationary population) has been analyzed, and simplifications of the results carried out separately for three different models of the net maternity function. It has also been shown the when mx drops abruptly to some m* x, where the form of m*x need not be specified except for the restriction that the resulting population will be stationary, the value of the index can be approximately obtained from I* = beoo (1 - rmu/2), where mu is the average age at childbearing of theinitial stable population.

Birth Rate↗