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Biomedical subjects

S McGuire

Publications and source records attributed to S McGuire.

At least 37 records · Page 2Linked to original sources
PubMed1994

Genetic and environmental influences on perceptions of self-worth and competence in adolescence: a study of twins, full siblings, and step-siblings.

Although it is generally assumed that the origins of adolescents' perceptions of self-competence lie in shared family environmental influences, the contributions of nonshared environmental or genetic influences have not been explored. We investigated sibling resemblance for perceived competence and self-worth in 720 adolescent pairs aged 10 to 18 years, using a twin, full sibling, and step-sibling design. Our goals were to assess the magnitude of shared and nonshared environmental influences and to disentangle resemblance due to shared genetic heritage from that due to shared environmental experiences. Shared environment was not significant for any of the scales. 4 of the subscales showed significant genetic influence: scholastic, social, physical, and athletic competence. We also explored possible sources of genetic influences on perceived competence. Bivariate models revealed common genetic variance between scholastic competence and vocabulary and social competence and sociability. These measures, however, did not account for all of the genetic variance in perceived social and scholastic competence.

Achievement↗
PubMed1984

Mast cells in pulmonary haemosiderosis.

A case of childhood pulmonary haemosiderosis with a fourfold increase in mast cells in the lung is described. This finding is discussed in relation to the pathogenesis of the disease. Comparison is made with controls, and the use of disodium cromoglycate is advocated.

Cell Count↗
PubMed1981

Chloride deficiency in Holstein calves from a low chloride diet and removal of abomasal contents.

Chloride deficiency signs were produced in young Holstein calves by a low chloride diet (.063% chlorine) and daily removal of chloride in abomasal contents. General clinical signs included anorexia, weights loss, lethargy, mild polydipsia, and mild polyuria. In latter stages of the deficiency, severe eye defects (scleral injection, sunken eyes, scaliness around eyes) and reduced respiration rate became evident. Feces contained varying amounts of blood and mucus. The chloride imbalance resulted in severe alkalosis and hypochloremia leading to secondary hypokalemia, hyponatremia, and azotemia. All deficient calves died after 24, 28, 38, and 46 days of treatment. Chloride concentrations of plasma in each of the calves just prior to death were similar at 31 to 35 meq/liter, which compares with normal 96 meq/liter. One additional calf made chloride deficient was recovered to normal health in 9 days following a single treatment with salt water and feeding of control diet containing .48% chlorine. Control calves fed a diet with .48% chlorine and which also had their abomasal contents removed daily grew normally and exhibited no deficiency signs. When dietary chloride was adequate, removal of abomasal contents (and chlorine) had no adverse effects on the animals.

Abomasum↗
PubMed1978

The extended experience: operationalizing the ideal.

In general, community health faculty who have utilized Extended Experiences think they provide a unique way of exposing students to working with various professional disciplines, learning about administrative processes and identifying ways in which the community attempts to meet the needs of population groups. It allows students to enlarge their perception of the community health nurses' role beyond the scope of home visiting. We think that experiences such as these would be rewarding attempts by other faculty in assisting students to learn the complex role of today's community health nurse.

Community Health Nursing↗
PubMedDate not supplied

Perceived competence and self-worth during adolescence: a longitudinal behavioral genetic study.

This investigation is the first longitudinal behavioral genetic study of self-concept during adolescence. It is a follow-up of a previous study examining genetic and environmental contributions to children's perceived self-competence and self-worth using a twin/sibling design. The study investigated adolescents' reports 3 years later and stability across two time points. Participants included 248 pairs of same-sex twins, full siblings, and stepsiblings between 10 and 18 years old. The results showed that six of the seven subscales were heritable at the second time point. None of the scales showed significant shared environmental effects. Longitudinal analyses revealed genetic contributions to stability for perceived scholastic competence, athletic competence, physical appearance, and general self-worth. Social competence, on the other hand, showed nonshared environmental mediation across time. These findings highlight the importance of genetically influenced characteristics and unique experiences as correlates of individual differences in self-concept during adolescence.

Adolescent↗
PubMedDate not supplied

Unusual presentation of primary sclerosing cholangitis.

A 23-year-old man presenting with acute pancreatitis and autoimmune hemolytic anemia was diagnosed with primary sclerosing cholangitis (PSC) without evidence of ulcerative colitis. This constellation of rare associations constitutes a unique mode of presentation of PSC. Within two years he also developed ankylosing spondylitis with sacroiliitis. Disordered immune regulation as a major factor in the mechanism of injury in PSC is supported by its increased association with other immunologically mediated disorders, most notably ulcerative colitis. Autoimmune hemolytic anemia, however, has been reported to be associated with PSC on only two occasions, and ankylosing spondylitis in the absence of ulcerative colitis is also unusual. In addition, the presentation of PSC with acute pancreatitis has rarely been described. This patient presented with several unusual features of PSC.

Acute Disease↗
PubMedDate not supplied

Clinicians post gains against HIV-related pain.

Presenters at a November 1994 symposium on issues of pain, argued that physicians too often undertreat or fail to treat pain in people with HIV. They suggested that the reasons include misplaced fear of inducing opiate addiction and of hastening death. Speakers emphasized that people with AIDS and their physicians must be persistent in diagnosing the causes and manifestations of pain, and must have the willingness to try different treatments and dosages to control pain and thus enhance patients' quality of life.

HIV Infections↗