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Biomedical subjects

S Martin

Publications and source records attributed to S Martin.

At least 757 records · Page 42Linked to original sources
PubMedDate not supplied

[Evaluation of the impact of individual antibiotic order forms on consumption of antibiotics].

The aim of the study was to assess the impact of an individual patient order form which concerned the 21 most costly antibiotics in a university hospital. Antibiotics expenditures were monitored from 1995 to 1999 and were expressed in 1999 French Francs per 100 patient days (p.d.). The time series were analyzed by auto-regressive models. The trend of antibiotics expenditures which were concerned by the individual patient order form was a yearly increase of 50 FF/100 p.d. (p < 0.01). The individual patient order form had no significant impact on global antibiotics expenditures but there were some differences across departments: antibiotics costs decreased 1.293 FF/100 p.d. (p = 0.02) in intensive care departments. Monitoring antibiotics consumption should be continued in order to increase power of analysis and to assess the impact of the implementation of guidelines.

Anti-Bacterial Agents↗
PubMedDate not supplied

Ultrastructural localization of Ca2+ in the Golgi apparatus of two different cell types.

The precipitation reaction with potassium oxalate was used to investigate the subcellular localization of Ca2+ in atrial myocardocytes and in Schwann cells of non-myelinated nerve fibers. Chelation with EGTA was used to prove the presence of Ca2+ in the electronoopaque deposits. In both cell types the oxalate reaction was intense in the classically described Ca2+ deposits: the perinuclear cisterna, the endo (sarco) plasmic reticulum, the mitochondrial matrix, but also in a novel localization: the cisternae of the Golgi stack in all cis to trans positions, suggesting that Golgi Apparatus is a major intracellular Ca2+ pool.

Animals↗
PubMedDate not supplied

Invasive cardiac procedures after myocardial infarction: which procedure when and its relationship to thrombolysis.

The availability and the now routine use of thrombolytic agents are important advances for therapeutic cardiology and the emergency care of patients experiencing AMI. The progression from ischemia to necrosis of cardiac muscle now can be aborted in a portion of this population by initiating thrombolytic infusions. Early use of thrombolysis in these patients has reduced acute myocardial infarction mortality and morbidity significantly. Although thrombolytic therapy has changed the course of treatment and survival after AMI, there may be time when this approach is contraindicated or unsuccessful. Alternative treatments that may be considered when thrombolytic agents cannot be given, or fail to ameliorate ischemia, are emergent percutaneous transluminal coronary angioplasty or coronary artery bypass graft surgery. Future interventional procedures such as intracoronary stents, atherectomy devices, and lasers may be considered as emergent treatment in the near future. It is important to have reviewed when these alternative invasive procedures, some of which are currently experimental, might be considered. Indeed, interventional procedures such as intracoronary stents, atherectomy devices, and laser delivery systems eventually may be accepted as primary therapies for the patient who arrives in the emergency department with an AMI. In the meantime, thrombolytic therapy administered as urgently as possible to appropriate patients with myocardial infarction is the most important goal.

Algorithms↗
PubMedDate not supplied

Positive AIDS.

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Acquired Immunodeficiency Syndrome↗
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President's message.

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Education, Nursing↗