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Biomedical subjects

S Mandal

Publications and source records attributed to S Mandal.

At least 73 records · Page 4Linked to original sources
PubMed1986

Role of corpora-allata and brain of adult female Lohita grandis gray.

Removal of the corpora allata from the emerging female adults of L. grandis caused a rapid and significant increase in the contents of total carbohydrate, glycogen, total lipids, cholesterol, total proteins and RNA in the fat body, and a significant drop in the contents of trehalose free fatty acids (FFA), phospholipids, free amino acids (FAA) and also in the activity of acid and alkaline phosphatase, glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT) and exterase in the fat body, in comparison with the sham-operated controls. Treatment with juvenile hormone analogue (JHa) of the allatectomized insects significantly reverses the effects produced by allatectomy (P less than or equal to 0.01). Similarly, removal of the brain produced similar responses in the fat-body but with some exceptions such as the decrease of total protein and RNA and increase significant of FAA as compared to the sham-operated controls. Simultaneous removal of corpora-allata and brain produces a rapid increase in the contents of total carbohydrate, glycogen, total lipid, cholesterol, FAA and the activity of acid phosphatase in comparison with all other treatments performed in this study, while the contents of trehalose, phospholipid, FFA, total protein, RNA and the activity of GOT, GPT, general esterase and alkaline phosphatase in the fat-body decreased compared to all other treatments. The results obtained are discussed in relation to the neuro-endocrine control of metabolism in insects.

Animals↗
PubMed1985

Adenohypophysial cell types in an Indian freshwater major carp, Catla catla (Hamilton).

The different adenocytes in an Indian freshwater major carp, Catla catla (Hamilton) have been studied by employing various modern staining techniques. Altogether, 8 different cell types have been reported in the adenohypophysis of the aforesaid fish. Variations in the staining intensities of the cell types with the different techniques adopted have been detailed.

Animals↗
PubMed1985

Biochemical changes in testis and ovary of Chrysocoris stolli Wolf. after the application of juvenoid and ecdysterone.

The changes in the metabolic status of both testis and ovary of Chrysocoris stolli following the treatment with juvenile hormone analogue (JHa) and ecdysterone were studied. After the exogenous application of JHa in selective dose, total carbohydrate, glycogen, trehalose, cholesterol, ascorbic acid and inorganic phosphorus increased significantly whereas free fatty acid (FFA), phospholipid, total protein, RNA and DNA decreased significantly in comparison to control of both testis and ovary. Total lipid significantly decreased in testis and significantly increased in ovary after JHa injection. The activities of cellular enzymes like alkaline phosphatase, 5' nucleotidase, catalase and peroxidase significantly decreased while acid phosphatase and GPT significantly increased after the JHa application in comparison to control both in testis and ovary. Activities of GOT and general esterase significantly decreased in testis and increased in ovary after JHa application. The exogenous application of ecdysterone also brought about the similar kind of responses as was noticed in case of JHa treatment but these two treatments differed in some cases such as ecdysteroid that produced some results which were just the reverse of what was produced by JHa treatment. The results obtained here were explained in terms of mode of action of these two hormones.

Animals↗
PubMed1982

Succinate dehydrogenase, monoamine oxidase and glutamine synthetase in developing human foetal brain regions.

In human foetal brain ontogeny the cerebral activity of succinate oxidoreductase (EC 1.3.99.1), i.e. succinate dehydrogenase (SDH), is higher than the cerebellar activity. With rise in foetal body weight the activity in all the brain regions gradually declines. SDH in all the brain regions shows two high-activity periods, one at 20-35 g and another at 110-220 g body weight. The enzyme exhibits a craniocaudal pattern of development. At all times of gestation, L-glutamate:ammonia ligase (EC 6.3.1.2), i.e. glutamine synthetase, activity in the spinal cord and medulla is higher than in the other three regions. At 190 g body weight glutamine synthetase shows an activity peak in all brain regions. Monoamine:oxygen oxidoreductase (EC 1.4.3.4). i.e. monoamine oxidase (MAO), is present much before the onset of electrical activity. It develops caudocranially and exhibits a biphasic pattern of development in all the regions. It increases considerably in the medulla and the spinal core towards late gestational periods.

Body Weight↗
PubMed1982

Effect of brain monoamines on the secretion of adrenocorticotrophic hormone.

The role of brain monoamines (5-HT, NA and DA) in the secretion of adrenocorticotrophic hormone (ACTH) was studied in view of contradictory reports. Plasma corticosterone levels and the rate of synthesis of corticosterone in vitro by the adrenal gland were estimated in albino rats and have been taken as the index of ACTH activity. These estimations were done in unstressed and stressed, and in untreated and treated rats. Drugs were administered intracerebroventricularly to the rats to cause selective degeneration of tryptaminergic, noradrenergic or dopaminergic neurons. The results show that plasma corticosterone levels and the rate of synthesis of corticosterone were significantly decreased after selective degeneration of tryptaminergic neurons in unstressed rats. After selective degeneration of either tryptaminergic or noradrenergic neurons, the acute increase in the plasma corticosterone levels and rate of synthesis of corticosterone in vitro by adrenal glands in stressed rats were significantly inhibited. These results have been interpreted to suggest that the central tonic control on adrenal glands may be 5-HT mediated and that during stress ACTH secretion may be both 5-HT and NA mediated. DA does not seem to have significant role in the regulation of ACTH secretion.

5,6-Dihydroxytryptamine↗
PubMed1981

Quantification of protease, amylase and lipase in the gut of Schizodactylus monstrosus during the postembryonic developmental stage. Effect of starvation, stress and topical application of juvenile hormone analogue.

A quantitative picture is presented on the activities and distribution of three major digestive enzymes in the postembryonic and adult stages of Schizodactylus monstrosus. The activity of enzymes in adult insects of both sexes has also been studied under starvation stress and after the topical application of juvenile hormone analogue. Results show that amylase activity was much higher in the early stages of development while in later stages protease and lipase activity was more significant. Protease activity was highest in the adult male, while the activity of all the enzymes reached its maximum in pregnant females. Starvation stress in adult individuals led to a slight decline of enzyme activity which was insignificant statistically. Topical application of JHa in high doses caused a steady increase in the activity of all the enzymes of which the increase of protease was statistically significant. The probable reasons for the quantitative variation have been discussed.

Administration, Topical↗
PubMedDate not supplied

Pseudohypophosphatasia.

Two rare cases of pseudohypophosphatasia in two siblings which so far, to best of our knowledge have not been reported.

Alkaline Phosphatase↗