In patients with rheumatoid arthritis and in healthy controls a continuous rise in acid phosphatase activity was observed in PHA-stimulated lymphocytes and the activity index was higher in patients than in controls. Differences were also observed between these groups in the activity of nonspecific esterase, beta-glucuronidase, and glycogen content at different hours of culture.

Acid Phosphatase↗

PubMedDate not supplied

The coexistence of mutilating rheumatoid arthritis, progressive systemic sclerosis and polycythemia vera--a case report.

A 41-year-old patient with mutilating rheumatoid arthritis and progressive systemic sclerosis, who developed a chronic myeloproliferative disorder polycythemia vera was observed. Some of the pathogenetic aspects of this case with special respect to the function abnormalities of peripheral blood polymorphonuclear cells are analyzed.

Adult↗

PubMedDate not supplied

[The heteroglycan profile of acute phase proteins in the differentiation of inflammatory processes].

In the last few years, several studied concerning an alternation in pattern of glycosylation of acute phase protein (APP) have been carried out in human sera, using especially affinity electrophoresis with lectins. Significant differences in the profile of glycosylation of APP in sera of patients with "acute" (e.g., sepsis) and "chronic" (e.g., rheumatic arthritis) inflammation have been observed, which suggest that the determination of microheterogeneity of APP appears to be a very useful differentiating test in clinical rheumatology.

Acute-Phase Proteins↗

PubMedDate not supplied

[Pentaxins: their structure and function].

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Alpha-Globulins↗

PubMedDate not supplied

[Mechanisms of autoimmunization].

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Antibodies, Anti-Idiotypic↗

PubMedDate not supplied

Cytochemical studies of peripheral blood granulocytes and lymphocytes in patients with systemic lupus erythematosus.

Using cytoenzymatic methods the activity of acid and alkaline phosphatase, non-specific esterase and glycogen content in peripheral blood cells were analyzed. A statistically significant rise in the activity of these enzymes was demonstrated in granulocytes and lymphocytes and a low level of glycogen in lymphocytes. Following prednisone treatment a statistically significant decrease was observed in the activity of studied enzymes and a rise in glycogen content.

Acid Phosphatase↗

PubMedDate not supplied

Effect of aggregated human gamma-globin on leukocyte migration-inhibitory test in patients with rheumatoid arthritis.

In 69 patients with rheumathoid arthritis (RA): 49 sero-positive and 20 sero-negative for rheumatoid factor and in a group of 20 healthy blood donors the leukocyte migration-inhibitory test was carried out. Heat-aggregated gamma-globulin was used in the culture medium as antigen. Both groups of patients exhibited a significant inhibition of migration, as compared with the group of healthy subjects. However, a significant difference in the mean value of the migration indices between the sero-positive and sero-negative individuals was observed.

Arthritis, Rheumatoid↗