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Biomedical subjects

S M Yang

Publications and source records attributed to S M Yang.

60 records · Page 4Linked to original sources
PubMed1983

[Macroscopic observation of progression of colorectal cancer].

Resected or polypectomized materials of colo-rectal cancer are morphologically analyzed in order to estimate their developing pattern. A retrospective review of previous radiological or endoscopic findings is also made in the patients who had either or both of examinations in the past. Morphologically, a distribution chart of colo-rectal cancers by their size and height is made, and a zone of colo-rectal cancers with the same morphological features is drawn. Retrospectively, type 1 advanced cancer appears to develop from Is type early cancer, and morphologically, a zone of Is type early cancers and that of type 1 advanced cancers partly overlap each other. The retrospective review also suggests that type 2 advanced cancer seems to develop from type Is, IIa or IIa + IIc early cancer. On the distribution chart, a zone of type 2 advanced cancer is partly superimposed over or bordered by that of early cancers type Is, IIa or IIa + IIc. Thus, it may fairly be said that advanced cancer develops from early cancer with its zone on the distribution chart partly superimposed over or bordered by that of the advanced cancer. Among early cancers, sessile type, superficial elevated type or elevated type with central depression may develop to advanced cancer. Both morphological analysis and retrospective radiological or endoscopic review of colo-rectal cancers would suggest the developing pattern of pedunculated or flat type early cancer.

Aged↗
PubMed1982

Serum high density lipoprotein cholesterol levels in Chinese healthy subjects and patients with certain diseases.

Serum high density lipoprotein cholesterol (HDL-C), total cholesterol (TC) and triglycerides (TG) were determined, and values of low density lipoprotein cholesterol (LDL-C), HDL-C/TC (%), and the LDL-C/HDL-C (ratio) were calculated in 1101 healthy Chinese men and women, 77 patients with coronary heart disease (CHD), 70 patients with cerebral vascular disease (CVD), 64 patients with diabetes mellitus (DM), 40 bilaterally oophorectomized women and 95 women using oral contraceptives. Serum HDL-C levels seemed higher and LDL-C levels lower in the healthy Chinese population as compared with those previously reported from European and American whites. Serum HDL-C was significantly higher in fertile females than in males of comparable ages. We failed to demonstrate any sharp fall in HDL-C after the menopause or bilateral oophorectomy. Serum HDL-C levels were significantly lower in both CHD and CVD patients than in healthy subjects of comparable sex and age. Concomitant increases in serum TC, LDL-C and TG, however, were found in CHD patients but not in CVD patients. No abnormality in the mean serum HDL-C level was found in DM patients. However, those complicated with CHD had significantly lower HDL-C than those without CHD. A striking serum HDL-C lowering effect was found with some kinds of oral contraceptives.

Adult↗
PubMedDate not supplied

Isolation of Guinea pig inner hair cells using manual microsurgical dissection.

Cochlear inner hair cells (IHCs) and outer hair cells (OHCs) show distinctive morphological features that are usually sufficient to distinguish these two species in vitro. However, OHCs may sometimes resemble IHCs when they are mechanically distorted or begin swelling at their basal end. As a result, accurately discriminating the cells based on morphology was thought to be problematic. An objective method that allows us to clearly and unambiguously distinguish these two cell types is therefore of continued interest. We describe a protocol in which solitary IHCs were harvested from guinea pig cochlea using a manual microsurgical dissection.

Animals↗