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Biomedical subjects

S M Moore

Publications and source records attributed to S M Moore.

16 recordsLinked to original sources

Teleradiology via narrow-band integrated services digital network (N-ISDN) and Joint Photographic Experts Group (JPEG) image compression.

The importance of remote access to both radiological images and medical information has stimulated many demonstration projects that use a variety of telecommunications providers' offerings. Teleradiology, through modest cost channels, can achieve adequate response times using a combination of narrow-band integrated services digital network (N-ISDN) and data compression. A demonstration project, developed in collaboration with Southwestern Bell Technology Resources, Inc, uses the aggregate bandwidth of two B channels (achieving a rate of 120 kilobits per second) and a block-oriented discrete cosine transform compression/decompression implementation based on the Joint Photographic Experts Group Standard for Still Image Compression. System response measurements for an Inquiry and Display Station accessing the Mallinckrodt Institute of Radiology's Radiology Image and Information Management Testbed via the N-ISDN connection show response times to be within 20 seconds. Viewing applications have been shown at sites within St Louis and at Radiological Society of North America, 1990, in Chicago.

Computer Communication Networks

"Smoking doesn't work:" a smoking prevention project for women attending a technical institute.

Women attending technical institutes often enroll in training programs for occupations with traditionally high smoking rates. In contrast, more worksites are implementing smoke-free and restricted smoking policies. "Smoking Doesn't Work," a smoking prevention project targeted at young females enrolled in a technical institute in Minnesota, used employability as the central theme in schoolwide events and classroom activities. Project intervention resulted in statistically significant increases in knowledge and awareness of smoking and employability issues. While young women enrolled in the technical institute recognized the negative image and health effects of smoking, they were less aware of the relationship between smoking status and employability. A focus on employability appears to provide a salient approach to smoking prevention with technical institute students.

Adolescent

A new nursing medium: computer networks for group intervention.

The PLWAs and the caregivers of persons with AD were similar in their adaptation to this new technology as a communication medium with nurses. Both groups availed themselves of the resources, both technological and personal, on the computer network. Although different in demographics, they also were similar in their ability to form and work in a traditional group structure. Nurses have historically intervened with groups, and this article demonstrates that nurses can intervene on a computer network with groups. Yalom's therapeutic factors exist in both non-face-to-face groups and traditional groups. The benefits of this technology to nurses are numerous: they can access clients in an efficient yet supportive manner; they can respond to multiple levels of need in multiple clients; and they can attend to emotional as well as more concrete needs of clients. The benefits to clients are also numerous: they can use the system at a time, frequency, and duration of their choice; they have the opportunity to be supported in self-care efforts versus being in a more dependent role; and they can engage in a normalization of their experiences. Computer networks can enhance nursing's ability to intervene with clients experiencing clinical problems.

Acquired Immunodeficiency Syndrome

A distributed approach to integrated inquiry and display for radiology.

Picture archive and communications (PACS) systems should be flexible and modular in design so that new advances in storage, computation, and display technology can be introduced into the system without a significant redesign of existing software. The acquisition, storage, and management of radiologic images must be carefully integrated with a radiology information system. Our architecture is based on a four-level data model: (1) patient information, (2) examination information and reports, (3) image information, and (4) instances of images. The PACS being developed at the Mallinckrodt Institute of Radiology within the Electronic Radiology Laboratory consists of three primary components: application clients, database servers and image servers. One type of application client is an image-capable workstation that supports a radiology image viewing application. The application client queries the database server for information regarding patient and examination data in response to user-level requests. The database server responds to the request by retrieving the appropriate patient demographics and examination information, along with a pointer to the image/instance data from a central database. The client then uses the image data pointer to query the image server for the actual pixel data. The image server responds by transmitting the pixel data to the requesting application client or a designated auxiliary display device. Other clients act as image data acquisition nodes. Queries to the database servers are made via a library of callable subroutines. Software integrity is maintained throughout the system by dynamically loading software from a code-control database. Inquiry and display transactions, supported on a local-area network (Ethernet), have been measured and analyzed. Results and observations are presented.

Computer Communication Networks

Condoms and coitus: adolescents attitudes to AIDS and safe sex behavior.

This study investigated the relationship between sexual risk taking and attitudes to AIDS precautions among a sample of approximately 1000 non-virgin adolescents attending 15 colleges and universities in Victoria, Australia. Four attitudinal dimensions were isolated: Antiprecautions, Risk Denial, Abrogation of Responsibility and Fatalism. These attitudes showed meaningful relationships with different types of sexual risk: risk with a casual partner, risk with a regular partner, and multiple partnering. Different patterns of association emerged for males and females, with female risk behavior being more strongly related to antiprecautions attitudes. These differences were discussed in the light of gender-stereotypic responses to sexual situations, and their implications for educational interventions were explored.

Acquired Immunodeficiency Syndrome

Developmental status and AIDS attitudes in adolescence.

We postulated that among adolescents and young adults, the development of consistent and responsible attitudes with respect to acquired immunodeficiency syndrome (AIDS) precautions would follow a pattern similar to that of the development of a sense of identity. Late-adolescent trainee teachers and nurses (N = 262) were administered identity and intimacy measures and a questionnaire measuring attitudes toward and knowledge of AIDS prevention. Attitudes were shown to be conceptually complex, with dimensions expressing the identity statuses of diffusion, foreclosure, moratorium, and achievement. Few relationships were found between AIDS attitudes and sex, course, measures of identity, or intimacy. However, attitudes toward AIDS precautions and identity status were predictive of future intention to use a condom. Intimacy level was negatively related to such an intention, suggesting that those in steady relationships may not recognize the need for AIDS protection.

Acquired Immunodeficiency Syndrome

ComputerLink: electronic support for the home caregiver.

Computers have become ubiquitous in contemporary society, as has the demand for home care for the elderly. Caregiving is recognized as a normal experience across the life span, and nurses must develop innovative responses to support caregivers. Computer networks offer caregivers access to a wide range of services such as communication, information, and decision support. Presented here is an interim report of a randomized field experiment demonstrating the feasibility of computer networks as a mechanism for delivering nursing services to caregivers of persons with Alzheimer's disease. Caregivers can and do use the computer network in home care.

Adult

The use of home-based computers to support persons living with AIDS/ARC.

Care of the patient at home challenges nurses with both the quantity and diversity of services required. New technologies such as computer networks may provide mechanisms to relieve the burden on traditional services, while opening new ways to meet the unique needs of home-based patients in a timely and effective manner. Capitalizing on an existing, free, public-access computer network, we developed the ComputerLink, a computer network designed to provide home-care support to persons living with acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC) in the community. In the pilot study presented here, we demonstrate the feasibility of using home-based computer networks to provide information, communication, and decision assistance to persons living with AIDS (PLWA). The success experienced with this particular group of patients provides sufficient encouragement to further test this intervention with PLWAs and to extent this nursing intervention to other groups of community-based patients.

Acquired Immunodeficiency Syndrome

Vitiligo: care and treatment.

Vitiligo is a condition of hypopigmentation. An overview of the diseases and treatment options are discussed. A case study is presented in which encouraging results have been obtained using PUVA and fluocinonide. Nursing considerations are listed.

Adult

Diethylstilbestrol potentiates and testosterone antagonizes the action of 3-methylcholanthrene on benzo(a)pyrene metabolism in Hep G2 cells.

We have used the human hepatoma cell line, Hep G2, to examine the ability of hormones and xenobiotics to modulate the hepatic induction of benzo(a)pyrene hydroxylase and epoxide hydrolase. Hep G2 cells were cultured in Eagle's Minimum Essential Medium supplemented with 10% fetal calf serum. 3-Methylcholanthrene, diethylstilbestrol, testosterone propionate, and combinations of 3-methylcholanthrene, and each of the hormones were added directly to the culture media. We subsequently studied the metabolism of benzo(a)pyrene using cell lysates of the Hep G2 cells. Metabolites were quantitated by high-performance liquid chromatography (HPLC) using fluorodetection. Exposure to 3-methylcholanthrene alone resulted in an eightfold increase in total benzo(a)pyrene metabolites with a change of the predominant metabolite from the 3-hydroxybenzo(a)pyrene to the carcinogenic pathway of the benzo(a)pyrene-7,8-diol. Diethylstilbestrol and testosterone propionate resulted in small, but significant, decreases in metabolism of benzo(a)pyrene. When exposed in combination with 3-methylcholanthrene, testosterone propionate antagonized and diethylstilbestrol potentiated the metabolism of benzo(a)pyrene. 3-Methylcholanthrene, diethylstilbestrol, and combinations of 3-methylcholanthrene and diethylstilbestrol or testosterone propionate resulted in increased epoxide hydrolase activity as compared to controls. These results, carried out in a human hepatoma cell line, lend support to a concern for potentiated toxicity and carcinogenicity following exposure to complex chemical mixtures.

Benzo(a)pyrene

Adolescents' attitudes towards AIDS precautions and intention to use condoms.

This study investigated attitudes toward AIDS precautions of 370 15- and 16-yr.-old secondary school students. Attitudes reflected levels of apathy, denial, and confusion high enough to lead to concern for this potentially high-risk group. Intention to use condoms in future sexual encounters was related to sex, conflict and confusion about AIDS precautions, plus other attitudinal variables.

Acquired Immunodeficiency Syndrome

Hypertension in valvar aortic stenosis.

The indirect arterial blood pressure in 50 cases of catheter-proven aortic stenosis without significant incompetence was examined. Defining the upper limit of normal blood pressure as 140/90mmHg, 14 percent had borderline, 18 percent had mild and 8 percent had severe hypertension. There was a significant positive correlation of systolic and diastolic blood pressure with age; ie pressures rose with age. The rate of increase was virtually identical with that of the normal population except for those over 70. Hypertension interferes with reliable clinical and haemodynamic quantitation of the valve lesion. The two lesions summate to increase the systolic burden on left ventricle.

Adolescent

A five-year study of mortality in a busy ski population.

A 5-year study of a busy ski population in Utah revealed a total at-risk period of approximately 3.5 million skier-days. While the morbidity (fractures, strains, sprains, and occasionally more severe injuries) associated with skiing is well recognized and considered by most physicians concerned to be distributed somewhat unevenly within the various skills of skiing, the authors have identified an exceedingly low mortality among the same population. Six individuals died as a result of injuries directly attributable to skiing. Three of these were considered to be advanced skiers and three were of intermediate skill. In three instances the environment was considered to play a role in the accident. Two of these victims were skiing out of control, one as a result of ice-covered snow and one as a result of speed in combination with a small jump. The third victim was crushed in an avalanche. One accident was completely unexplained, the skier having skied without apparent attempt at checking or change of course into a nonrecreational area. The two remaining skiers of intermediate skill both suffered injuries incident to falling forward with considerable force onto a relatively flat, hard snow surface. Notwithstanding the intense and sometimes prolonged exertion at relatively high altitudes (9,400 to 11,000 ft or 2.9 to 3.3 km), only one skier with a previous history of atherosclerotic heart disease died while skiing. One additional middle-aged skier with similar history died at the conclusion of the day.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent

A detection algorithm for multiform premature ventricular contractions.

This paper reports an algorithm developed to identify and quantify multiform PVCs. The algorithm clusters PVCs of similar morphology using a combination of time-domain and frequency-domain analysis. Initially, PVCs are grouped together on the basis of four time-domain-based morphological feature measurements. However, these time-domain-based clusters many times are nonunique because commonly encountered signal changes can cause substantial variations in the feature measurements of clinically similar beats. These redundant clusters are consolidated using two frequency-domain parameters: The First Spectral Moment (FSM) (center of gravity) of the amplitude spectrum, and the 5-Hz phase angle.

Cardiac Complexes, Premature