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Biomedical subjects

S M Johnson

Publications and source records attributed to S M Johnson.

At least 217 records · Page 12Linked to original sources
PubMed1975

Changes in numbers of acidophilic and basophilic connective tissue granulated cells in the intestine of the rat during the estrous cycle.

Changes in physiological reproductive states of female Long-Evans hooded rats were directly correlated with changes in the concentration of acidophilic and basophilic connective tissue granulated cells in the lamina propria of the duodenum. Acidophilic granulated cell numbers were significantly higher at estrus and metestrus than at other stages of the estrous cycle or in the immature state. apcidophilic granulated cell numbers during pregnancy were not significantly different from cell numbers quantified during metestrus, diestrus, or proestrus, but were significantly lower than cell numbers during estrus. Late lactation (21-25 days) was associated with significant decreases in the numbers of acidophilic granulated cells from numbers observed during the estrous cycle and during pregnancy. Basophilic granulated cell numbers did not differ significantly during the estrous cycle, although the highest numbers were observed during proestrus. Basophilic granulated cell numbers were significantly higher during pregnancy than during the estrous cycle. Basophilic granulated cell counts in late lactation were comparable to numbers quantified in estrus, metestrus, and diestrus, but were significantly lower than during proestrus and pregnancy.

Animals↗
PubMed1975

Normal versus deviant children. A multimethod comparison.

The present study investigated differences between referred and nonreferred children and their families on the basis of home and clinic observations and parent questionnaires. Subjects were 28 families with children between 4 and 8 years of age who had been referred to a clinic for acting-out behavior and 28 nonreferred controls matched on several variables. Home observation results indicated that referred children showed significantly more deviant behavior and less prosocial behavior than nonreferred children and that their parents emitted more negative and commanding behavior in contrast to the control group. Systematic observation in the clinic revealed significant differences only in parent negativeness and number of commands. Finally, all five factors of the parent attitude questionnaire yielded large and significant differences between groups. There was considerable overlap between groups on all behavior variables but less overlap on the parent attitude measure. Results from a stepwise discriminant analysis classified 90% of referred children and 90% of nonreferred children correctly on the basis of the parent attitude variable alone. Taken together, these results suggest that child behavior is not always the critical variable in referral and stress the importance of multiple assessment procedures for child-family problems when children are referred for treatment.

Attitude↗
PubMed1975

Multiple criteria follow-up of behavior modification with families.

This report presents termination and follow-up evaluations of a parent training program based on behavior modification principles. Treatment termination outcome data were obtained for 22 families, and follow-up data were collected on 14 of these families 3 and 8 months after treatment. Results indicated a fairly high level of success at termination on the basis of parent-collected observational data, parent attitude change toward the children, and parent attitude concerning the process and outcome of treatment. Modest levels of success were evidenced on the basis of behavioral data recorded by trained observers in the home. Families who participated in follow-up demonstrated greater cooperation and involvement with the treatment program than those who did not participate. In all other respects, however, these two groups were similar. Follow-up data on parent attitude measures demonstrated maintenance of the treatment effects. Parent observational data were incomplete, but also showed maintenance in follow-up. For the subsample of 14 cases, home observation records indicated a nonsignificant decline in deviant behavior at termination followed by a nonsignificant increase in deviant behavior during follow-up. The meaning and implications of these discrepant findings were discussed and compared with results from other laboratories.

Behavior Therapy↗
PubMed1975

Plasma-membrane-associated immunoglobulins and other polypeptides of pig mesenteric node lymphocytes.

Plasma membranes from pig mesenteric lymph-node lymphocytes contain a large number of polypeptide chains ranging in molecular weight from 20,000 to greater than 470,000, with a major component of 46,000. There are approx. 12-15 glycoproteins. The membranes contain immunoglobulin G, which comprises 0.6% of the total protein. Immunoglobulin M is also detected, but has not been accurately quantified for technical reasons. Possible origins of the membrane-associated immunoglobulin are briefly discussed. It is concluded that the immunoglobulin is probably associated with the plasma membrane in the intact cell.

Animals↗
PubMed1975

Reactivity to home observation: a comparison of audio recorded behavior with observers present or absent.

THE STUDY COMPARED THE BEHAVIOR OF FAMILY MEMBERS AT HOME AS RECORDED BY AUDIOTAPE RECORDINGS IN TWO CONDITIONS: with an observer present or absent. Behavioral differences were expected as a function of differential reactivity to these observational procedures, but none was found, and there was no evidence of adaptation effects in either condition. In general, significant positive correlations were obtained between the rates of recorded behavior in both situations. The implications of these findings for the development of nonreactive observation procedures were discussed.

Journal Article↗
PubMed1975

Parental manipulation of the behavior of normal and deviant children.

The present study examined the ability of parents to bias home-observation data by influencing their child's behavior in socially desirable and undesirable directions. Parents of 12 deviant and 12 non-deviant boys, aged 4-8, were given the response set to present their child as "good", "bad", and usual (normal) during 6 45-minute observations of family interaction. Deviant and non-deviant children showed significantly more deviant behavior under the bad condition as compared with normal, whereas their good and normal conditions did not differ. Parent positive and negative behaviors were related to changes in child deviant behavior for the deviant sample; parent positive and commanding behaviors were related to changes in child deviant behavior for the nondeviant sample. Parent self-report of behavior change was generally consistent with the observation data. The results suggested implications for naturalistic observations of families and for child behavior change interventions.

Adult↗
PubMed1974

Parental manipulation of child behavior in home observations.

The object of this study was to investigate the extent to which parents can manipulate their children's behavior in home observations. Twelve families with four- to six-year old children were recruited for the research. The parents were instructed to make their child look "bad" or "deviant" on three days of a six-day observation and to look "good" or "nondeviant" on alternate days. Results indicated that, as predicted, the rate of child deviant behavior, parental negative responding, and parental commands were all significantly higher on bad than good days. Parental responses to questionnaires provided more detailed information on how parents felt that they influenced their children in the desired directions. These results were discussed in terms of their implications for child psychopathology and the methodology of data collection in the natural environment.

Journal Article↗
PubMed1972

Timeout duration and the suppression of deviant behavior in children.

The effects of three different timeout durations were investigated in a group of 20 retarded, institutionalized subjects. Each subject received 1, 15, and 30 min of timeout in a design that was counterbalanced in terms of the order in which timeout durations were presented. Displays of deviant behavior-such as aggression, tantrums, and self-destruction-were followed by periods of isolation in a timeout room. A reversal design was employed such that return-to-baseline periods were instituted after each timeout period. The overall effect of timeout was to reduce significantly the rate of deviant behavior. On the average, 15 and 30 min produced a 35% decrease in deviant behavior with little difference between the effectiveness of 15 and 30 min. The range of effects in all timeout conditions varied widely. The sequence in which the 1-min duration was presented effected the direction of its effect. When it preceded the use of longer durations, 1 min was most effective. As it came later in the sequence, its suppressive characteristics became less reliable.

Journal Article↗