Biomedical subjects

S M Horner

Publications and source records attributed to S M Horner.

23 records · Page 2Linked to original sources

PubMed1992

A comparison of cardioversion of atrial fibrillation using oral amiodarone, intravenous amiodarone and DC cardioversion.

Fifty-two consecutive patients with atrial fibrillation underwent 86 episodes of attempted cardioversion with oral amiodarone, intravenous amiodarone or DC cardioversion. The presence of chronic obstructive pulmonary disease or a presenting heart rate of less than 110 beats per minute were associated with a favourable outcome. Conversion to sinus rhythm was achieved in 29% of the group treated with oral amiodarone, 42% of the group treated with DC cardioversion and 64% of the group given intravenous amiodarone. The overall statistical significance of this distribution on chi square testing was p < 0.032. However when only first attempts at cardioversion were analyzed there was no difference between intravenous amiodarone and DC cardioversion.

Administration, Oral↗

PubMed1989

Chest pain--no difference in severity between those having a myocardial infarction and chest pain from other causes.

In considering nonpleuritic chest pain, the severity of the maximal pain as indicated by the patients on a visual analogue scale does not significantly differ for myocardial infarction or chest pain of other origin. There is also no significant change with time in the severity score of the maximal pain for either group. Thus, the time course is not diagnostically useful.

Angina Pectoris↗

PubMed1988

Aspergillus endocarditis in association with a false aortic aneurysm.

A 32-year-old man was admitted with an intracerebral hematoma and subsequently with bilateral femoral emboli five months after aortic valve replacement. Blood cultures for bacteria and fungi were negative but microscopy of the embolus revealed Aspergillus fumigatus. At operation a large false aneurysm of the ascending aorta and vegetations on the prosthetic aortic valve were found. Aspergillus endocarditis is diagnosed antemortem in only 23% of fatal aortic aneurysms: blood cultures are positive in only 8%. Clinically a large vessel embolus is characteristic, being present in 83% and microscopy and culture of such an embolus if present are vital investigations.

Adult↗

PubMed1988

The proliferation of medical papers in several countries after discoveries in cardiology.

The numbers of papers on the Medline database concerning seven innovations in cardiology in the last 20 years were ascertained by year from the time of their discovery until the present. They were further divided into three geographical regions. The proliferation of papers in medical journals regarding new discoveries is initially exponential, with a plateau phase which is unrelated in magnitude to the constants in the model for the exponential phase. The magnitude of the plateau phase in the case of drugs is related to the number of indications for use of the drug. The proliferation of papers on a particular subject in English journals lags behind journals from the United States of America and the rest of the world. Eventually there are a larger number of papers published per year, per head of the population or per doctor in England than in the U.S.A. Current computer databases are not satisfactory for research audit. The department within an institution and an assessment of the quality of the research should be available.

Cardiology↗

PubMedDate not supplied

Medical management of endocarditis.

The treatment of infective endocarditis with antibiotics is one of the great medical success stories of this century, reducing mortality from 100% to as low as 10%. It is important for all medical and dental practitioners to be aware of endocarditis as the disease may be inadvertently caused by the treatment of other conditions.

Aftercare↗