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Biomedical subjects

S M Hassan

Publications and source records attributed to S M Hassan.

At least 19 recordsLinked to original sources
PubMed2006

Visceral leishmaniasis and tuberculosis in patients with HIV co-infection.

We describe here two cases, one male and one female, both age 40 years, with visceral leishmaniasis and HIV-1 co-infection. The female patient had features of Koch's abdomen. The male patient had features of tuberculous lymphadenitis and bilateral pleural effusion more marked on the right side. Both were treated with highly active antiretroviral therapy, antituberculous drugs, antibiotics, antifungal medicine (fluconazole) and miltefosine. Both patients showed marked improvement with therapy.

Adult↗
PubMed2005

Egg storage period and weight effects on hatchability of ostrich (Struthio camelus) eggs.

We studied the affects of storage period and egg weight on the hatchability of 314 ostrich (Struthio camelus) eggs. Eggs were stored at 20 degrees C and 65% RH before incubation at the Poultry Research, Teaching and Extension Center at Texas A&M University (College Station, TX). Eggs were classed by storage period (< or = 5, > 5 < or = 10, > 10 < or = 15, or > 15 < 24 d) and egg weight (< or = 1,450, > 1,450 < or = 1,650, or > 1,650 g) to determine the influence of storage period and egg weight on hatchability, egg weight loss, incubation period, and absolute and relative chick weights. Eggs were incubated at 36.5 to 37.0 degrees C and 25% RH through 38 d of incubation and 36 degrees C and 30% RH thereafter. Mean egg weight loss was greater from eggs of the longest storage period group (> 15 < 24 d) at 21 or 38 d when compared with eggs of the shorter storage periods, but there were no differences at 7, 14, or 28 d among all storage period groups. Mean hatchability was higher in eggs stored < or = 10 d than eggs stored > 15 < 24 d, but hatchability of eggs stored >10 < or = 15 d was not different from eggs stored < or = 10 d or > 15 < 24 d. Incubation period was longer, and absolute and relative weights were higher in eggs stored >15 d than was observed in eggs stored < or = 15 d. Negative correlations were detected between egg weight and moisture loss at 38 d (-0.55) and between hatch time and moisture loss (-0.25). Hatchability was higher in small eggs than medium eggs (< or = 1,650 g). A positive correlation was observed between chick and egg weights (0.84). The results indicated that storage period and egg weight affected egg weight loss. Our results suggested that the most effective storage period was less than 15 d to maintain hatchability for ostrich eggs when incubated at 36.5 to 37.0 degrees C with 25% RH.

Animals↗
PubMed2005

Natural infection rates and transmission of Theileria annulata by Hyalomma anatolicum anatolicum ticks in the Sudan.

Hyalomma anatolicum anatolicum nymphs were collected from two localities in the Sudan: Eddamer in Northern Sudan and Wad-Medani in Central Sudan. They were allowed to moult to adult ticks, which were assessed for Theileria infection in their salivary glands using Feulgen stain. At Eddamer, 49.6% of 123 ticks examined were infected with Theileria and the mean intensity of infection was 1.3 (i.e. the number of infected acini/number of infected ticks). At Wad-Medani, 8.6% of 162 ticks were infected and the mean intensity of infection was 7.9. The prevalence of infection was higher in female than in male ticks at both localities. When adult H. a. anatolicum were applied onto two susceptible calves, both animals developed the severe form of theileriosis.

Animals↗
PubMed2004

Incubation temperature for ostrich (Struthio camelus) eggs.

The impact of incubation temperature on egg weight loss, embryonic mortality, incubation period, hatchability, and chick weight in 394 ostrich (Struthio camelus) eggs was studied. Eggs were obtained from 3 farms in Texas. Three incubation temperatures (36.5, 37.0, or 37.5 degrees C) with relative humidity ranging from 20 to 30% were used. Results showed that incubation of fertile eggs at 36.5 degrees C increased hatchability and incubation period in comparison with other treatments. The incidence of dead in shell and total dead embryos was increased at 37.5 degrees C when compared with 36.5 degrees C. No differences in hatchability, incubation period, dead-in-shell embryos, and total dead embryos were observed between eggs incubated at 37.0 or 37.5 degrees C. Neither chick weight nor egg weight loss at 7, 14, 28, or 38 d of incubation was affected by incubation temperature, but egg weight loss at 21 d was lower for eggs incubated at 37.5 degrees C than for the other treatments. Results show that the most effective incubation temperature for the ostrich is lower than the most effective incubation temperature for most bird species.

Animals↗
PubMed2004

Preliminary survey of ticks (Acari: Ixodidae) on cattle in northern Sudan.

In a cross sectional survey conducted during the period June 2001 to July 2002, the geographical distribution of ticks on cattle in the Sudan was determined. Seventeen locations were surveyed from Northern, Central, Eastern, Western, Blue Nile and White Nile Provinces. Total body collections of ticks were made from 20 cattle at each location. Four tick genera and 11 species were identified. The tick species collected included Amblyomma lepidum, Amblyomma variegatum, Boophilus decoloratus, Hyalomma anatolicum anatolicum, Hyalomma dromedarii, Hyalomma impeltatum, Hyalomma marginatum rufipes, Hyalomma truncatum, Rhipicephalus evertsi evertsi, Rhipicephalus sanguineus group and Rhipicephalus simus simus. Major ecological changes have occurred due to extensive animal movement, deforestation, desertification and establishment of large mechanized agricultural schemes. These factors have certainly affected the distribution of ticks and tick-borne diseases in the Sudan. The absence of A. variegatum and A. lepidum in northern Sudan was not surprising, since these tick species are known to survive in humid areas and not in the desert and semi-desert areas of northern Sudan. The absence of B. annulatus in northern and central Sudan is in accordance with the finding that this tick species is restricted to the southern parts of the central Sudan. The presence of H. anatolicum anatolicum in Um Benin in relatively high abundance is an interesting finding. The present finding may indicate that the southern limit of this species has changed and moved southwards to latitude 13 degrees N. It is concluded that major changes in tick distribution have taken place in the Sudan.

Animal Husbandry↗
PubMed2003

Effect of early feed restriction on reproductive performance in Japanese quail (Coturnix coturnix japonica).

Reproductive performance of quail (Coturnix coturnix japonica) was evaluated following feed restriction (100, 85, and 70% of ad libitum) between 2 to 5 wk of age with three replicates of 12, 2-wk-old chicks per replicate. Body weight, feed conversion, and leucocyte distribution were measured during feed restriction. After experimental feed treatment, BW, age at first egg, egg production, fertility, hatchability, and embryonic mortality were evaluated from five replicates of two females and one male per treatment. Feed-restricted female chicks had lower BW from 3 to 5 wk of age, but male weights were depressed only during the most severe restriction at 4 and 5 wk. No treatment differences were observed among BW within a sex from 6 to 13 wk. Body weights at first egg were significantly heavier for females fed 70% ad libitum than for birds on other treatments. Fertility, age at first egg, feed conversion, egg production, and egg weight were unaffected by feed restriction. Although hatchability was unaffected by feed restriction, percentage of late dead and total dead embryos were significantly reduced in eggs from restricted quail. Thirty quail fed 70% of ad libitum control intake had significantly increased egg specific gravity. Feed restriction increased the percentage of heterophils and basophils and the heterophil/lymphocyte ratio, whereas the percentage of lymphocytes and eosinophils decreased. Feed can be restricted to 85 or 70% of ad libitum feed intake from 2 to 5 wk of age without detrimentally affecting reproductive parameters between 6 to 13 wk of age.

Aging↗
PubMed2003

Effect of acetyl salicylic acid in drinking water on reproductive performance of Japanese quail (Coturnix coturnix japonica).

The impact of acetyl salicylic add (ASA) on reproductive performance during periods of heat stress was studied in Japanese quail (Coturnix coturnix japonica). During a season when daily high temperatures averaged between 34 and 40 degrees C, four treatments each containing four replicates of five males and five females were given 0, 0.5, 1.0, or 1.5 g/L ASA in drinking water from 34 to 45 wk of age. At 39 wk of age control quail were lighter than quail fed ASA. Quail receiving 1.5 g/L ASA exhibited increased fertility, hatchability, and egg production and decreased late dead and total embryonic mortality. Early dead embryos, pips, chick weight, and egg weight were not different among treatments. The lumen of uterovaginal junction sperm host glands (UVJSHG) from control quail was apparently devoid of spermatozoa, whereas quail receiving 1.5 g/L ASA had the greatest apparent accumulation of spermatozoa. Control caudal infundibulum host glands (CPOI) were devoid of spermatozoa in contrast with CPOI from quail receiving ASA. Results show that UVJSHG lumens from quail receiving 1.5 g/L ASA had larger inside diameters than other treatment groups. However, the CPOI inside diameter and the outside diameters of both UVJSHG and CPOI were not affected by ASA. Adding 1.5 g/L ASA to the drinking water of quail under heat stress improved body weight, fertility, hatchability, embryonic mortality, egg production, egg specific gravity, and sperm storage capacity.

Animals↗
PubMed2003

Effect of feeding time on the reproductive performance of Japanese quail (Coturnix coturnix japonica).

Several feeding regimens are applied to improve performance of fertile egg production during times of heat stress. During a period of heat stress (34 to 36 degrees C), two feeding periods were used to measure the impact of feeding time on reproductive performance of Japanese quail (Coturnix cotunix japonica) between 44 and 60 wk of age. Each feeding time treatment had 25 individually caged male and female pairs. Quail were fed ad libitum between 0600 to 1400 or 1400 to 2200 h daily. Results indicated that feeding between 0600 to 1400 h reduced BW, fertility, hatchability, egg production, and egg specific gravity when compared with the effects of feeding between 1400 to 2200 h. Feeding time had no effect on total embryonic mortality, egg weight, or the period between subsequent ovipositions. The different feeding times affected the distribution curve of oviposition over time. An instrument designed to record oviposition time is described. Results showed that selection of the time of day for application of an 8-h restricted feeding regimen affected BW, fertility, hatchability, egg production, egg specific gravity, and oviposition time in Japanese quail.

Animals↗
PubMed2002

Monitoring of cadmium in "on" and "off" date palms.

The study demonstrated that the mature dates we investigated were considered safe for human consumption. However, our findings revealed that much of the early fruit and leaves, which appeared at the advent of the fruiting season, possessed elevated levels of cadmium (Cd) that could accumulate in the food chain and thus impact adversely on the environment. In addition, animal feed for livestock contains date leaves, which should be restricted to the mature ones. The monitoring of cadmium in date palms is of considerable interest to environmental science and the thrust of this work, therefore, involved measurement, by ICP, of Cd in dates and corresponding leaf specimens, and evaluation of its distribution during the developmental stages of the fruiting season. Thirty-six date samples and 36 leaf specimens of the Fard cultivar were collected from "on" and "off" date palms during the Kimri, Bisir and Rutab stages of the fruiting season and subjected to suitable digestion procedures. Sample masses of typically 1 g (dry weight) were prepared in 25 ml dilute acid solution and investigated for trace levels of Cd by ICP-AES. Special attention was paid to contamination and the validation of our methodology. The Cd "threshold" in our study was 50 ng/g, in keeping with the levels of tolerance appearing in the literature. For the dates we found elevated levels of Cd [> 50 ng/g] in most of the samples, for both categories of "on" and "off" trees, during the Kimri stage. In the case of the leaves, the "on" samples revealed significant values up to 125 ng/g in Bisir, in some cases, but the trend for the "off" trees remained the same with the highest levels [> 100 ng/g] recorded during Kimri. Safe levels were attained during Rutab for all specimens. The possibility of a connection between Cd toxicity and the alternate-bearing phenomenon is discussed and this could be the subject of future interest.

Cadmium↗
PubMed2000

Reduction of halogenated hydrocarbons in aqueous media: I. Involvement of sulfur in iron catalysis.

Experiments were carried out to investigate the reduction of tri- and tetra-chloroethene with iron in aqueous solutions. Results indicate (i) dependence of the dehalogenation capacity of the iron on its sulfur content and (ii) that ethyne was the primary dehalogenated hydrocarbon for both compounds. A reaction mechanism based on in situ formation of ferrous sulfide as the catalyst and its reaction with the halocompounds in the presence of hydrogen has been postulated.

Acetylene↗
PubMed2000

Effect of case managers with a general medical patient population.

The objectives of this study were to evaluate the effect of inpatient case management (CM) on a general medical service and to determine if a prediction rule, identifying patients likely to need discharge planning services, could define a subset of patients for whom CM would be most effective. We hypothesized that CM would have greatest impact on patients predicted to be at highest risk of needing discharge planning to arrange for post-discharge medical services. We carried out a prospective controlled study. Six general medicine teams from a 600-bed urban teaching hospital were randomly assigned to CM (n = 4) or standard care (SC) (n = 2). Number of patients = 302 (207 CM; 95 SC). Case managers participated in daily physician team rounds and coordinated discharge planning for CM patients; SC patients received discharge planning from staff nurses or discharge planners when requested by physicians. The outcomes measured were deviation from the hospital length of stay (LOS) expected for a patient's diagnosis, patient satisfaction and non-acute medical service utilization during the month after discharge. Overall, patients from CM and SC teams did not differ in their deviation from expected LOS, post-discharge medical service utilization and patient satisfaction. However, after stratifying patients by their predicted need for post-discharge medical services, only patients in the 'high risk' category had a significantly shorter LOS under CM (2.9 days shorter than SC patients; P = 0.02). We concluded that, in this study, the effect of case managers on a general medical service was limited to shortening LOS only among a stratum of high risk patients.

Adult↗
PubMed1998

Do the diminishing efficacy and increasing toxicity of sodium stibogluconate in the treatment of visceral leishmaniasis in Bihar, India, justify its continued use as a first-line drug? An observational study of 80 cases.

Eighty parasitologically confirmed cases of visceral leishmaniasis (kala-azar) in Bihar, India, were treated daily with 20 mg sodium stibogluconate/kg for 30 days, to assess the current efficacy and toxicity of this 30-day regimen. Clinical and parasitological cure was obtained in 48 (60%) of the patients. However, 26 (33%) patients did not respond to the first course of treatment (primary unresponsiveness), two relapsed after initial clinical and parasitological cure, and two were withdrawn from the study (one on day 6 of treatment because of cardiotoxicity in the form of supraventricular tachycardia and the other on day 24 because of severe loss of appetite). All 30 patients who were not entirely cured with sodium stibogluconate were successfully treated with amphotericin B. Electrocardiographic changes occurred in many of the patients as the result of treatment with sodium stibogluconate. Diminution in the height of the T wave was seen in 32 (40%), inversion of the T wave (Minnesota code 5-1, 5-2) in seven (9%), elevation of the ST segment (Minnesota code 4-1) in three (4%), prolonged QT interval (compared with baseline findings) in six (8%), and diminution in the height of the P, R and T waves in two (3%). Cardiac arrhythmia occurred in five patients (6%), supraventricular arrhythmia (coarse atrial fibrillation) occurred in one patient and ventricular tachycardia, ventricular fibrillation, torsade de pointes and multifocal ventricular ectopics occurred in the four patients (5%) who died of cardiotoxicity. Minor side-effects, such as pain at the site of injection (two cases), mild diminution in appetite (12 cases), metallic taste in mouth (six cases), and joint pain (two cases), were also observed. It was concluded that the efficacy of sodium stibogluconate in the study area has declined over the years and that its toxicity has increased. A more efficacious, safer and cheaper, alternative drug is required as the first line of treatment of kala-azar.

Adolescent↗
PubMed1997

The impact of Ixodiphagus hookeri, a tick parasitoid, on Amblyomma variegatum (Acari: Ixodidae) in a field trial in Kenya.

In an experiment to investigate the effect of the tick parasitoid, Ixodiphagus hookeri, on tick numbers on cattle, 150000 parasitoids were released over a period of 1 year in a field where ten cattle infested with multiple tick species were kept. Amblyomma variegatum was reduced from 44 to two ticks per animal while Rhipicephalus appendiculatus increased over the time of parasitoid release. During the time of release 51% of the nymphs of A. variegatum collected from the animals were parasitized. The recovery of the parasitoids after the releases were stopped was only 9%. The total numbers of A. variegatum remained low up to 1 year after the parasitoid release was stopped. This study gives an insight into how I. hookeri could be used strategically for the management of A. variegatum on small-scale farms.

Animals↗
PubMed1997

Amphotericin B is superior to sodium antimony gluconate in the treatment of Indian post-kala-azar dermal leishmaniasis.

Parasitologically confirmed cases of post-kala-azar dermal leishmaniasis (PKDL) were treated by infusion with amphotericin B deoxycholate (ABD; 1 mg/kg.day on days 1-20, 21-40 and 61-80) or by intramuscular injection with sodium antimony gluconate (SAG; 20-day courses at 20 mg/kg day, with 20-day, drug-free intervals). Of the 11 patients given ABD, all were cured with the three courses, none relapsed in 12 months of follow-up, all developed mild adverse effects (shivering and fever) because of the infusion, five lost their appetites, and three showed increases in their serum creatinine concentrations (although none exceeded 'normal' limits). In contrast, only seven (63%) of the 11 patients given SAG were considered treatment successes (improvement in lesions by the end of the third course) and these took six courses (two cases), nine courses (four cases) or 10 courses (one case) to cure completely. Two of the patients given SAG developed arthralgia and two others developed non-specific ST changes in their electrocardiograms (ECG), although their ECG were normal between courses. The better cure rate with ABD was not statistically significant, probably because of the small sample size. However, ABD appears to be a superior to SAG in terms of the speed of response and cure, although it is more expensive and has some nephrotoxicity. As the effectiveness of SAG against PKDL is apparently declining over time and the cost of ABD is prohibitive in poor countries such as India, a safe, cheap and more effective drug for the treatment of PKDL is needed.

Adolescent↗
PubMed1996

Payer-hospital collaboration to improve patient satisfaction with hospital discharge.

BACKGROUND: Brigham and Women's Hospital, in Boston, and its major health maintenance organization (HMO), Harvard Community Health Plan, collected data in spring 1994 which revealed that patients were less satisfied with hospital discharge planning than with other elements of care. PROBLEM IDENTIFICATION PROCESS: An interdisciplinary team, formed in November 1994 and composed of eight members from the hospital and HMO, used data from the hospital's Patient Satisfaction Survey, flowcharting, and phone interviews with patients to identify discharge planning-related problems. For example, follow-up contact with patients after discharge was erratic and no clear signal of the successful "hand off" of care from the hospital team to the community team existed. IMPROVEMENT CYCLE 1: Eighty-three percent of the payer's patients that received the improvement strategy developed by the interdisciplinary team-a concierge service-rated discharge planning as excellent or very good, compared to 63% of control patients. IMPROVEMENT CYCLE 2: PLAN SOLUTIONS/STRATEGIES FOR IMPROVING HOSPITAL DISCHARGE PLANNING: The results of the team's Cycle 1 improvement provided information for the team to use in designing a second cycle of incremental improvement activity. For example, to address the lack of clarity about who was responsible for making decisions about discharge and follow-up care, the attending physician was designated the transition-of-care coordinator. Once all the improvements were implemented, Cycle 2 patients who received the intervention rated satisfaction with discharge higher (83% versus 73%) than the control group. CONCLUSIONS: Implications of hospitalwide implementation of discharge planning-related services attempted on one unit are being considered.

Ancillary Services, Hospital↗