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Biomedical subjects

S M Ellis

Publications and source records attributed to S M Ellis.

33 records · Page 2Linked to original sources
PubMed1983

Health professionals' guide to managing patients with Alzheimer's disease and their families.

Caring for the institutionalized patient with Alzheimer's disease is complicated by the patient's deterioration in communicating, self-care and mobility. Verbal repetition, memory aids and a set routine help maintain the patient's emotional and mental control. Regular exercise helps maintain the patient's physical well-being. Families of patients with Alzheimer's disease also need special support.

Aged↗
PubMed1976

Maternal thyroid function, iodine deficiency and fetal development.

In an area of New Guinea where there is dietary iodine deficiency, measurements of thyroid function have been made on women of child-bearing age, several of whom were pregnant at the time. The outcome of these pregnancies, and also of those occurring in the four preceding years, were examined in relation to indices of thyroid function. More stillbirths, infant deaths and endemic cretins occurred among the offspring of women who showed biochemical evidence of iodine deficiency, without clinical evidence of hypothyroidism. This situation differs from that of untreated myxoedema or congenital hypothyroidism in women, which is usually associated with altered menstrual function, infertility or repeated abortion. Mechanisms that may account for these differences and the possible implications are discussed.

Child, Preschool↗
PubMed1975

Is "T4 toxicosis" a normal biochemical finding in elderly women?

The lack of equivalence in the distrubtion of normal ranges for free thyroxine index (FT4I) and free triiodothyronine index (FT3I) in the over sixty-five age-group, as compared with the fifteen-sixty-five age-group, supports the idea that "T4 toxicosis" is a common biochemical finding in elderly women. The disparity between FT4I and FT3I ranges was also reflected in the true free T4 and free T3 levels which were measured in some cases. These results suggest that when an increased FT4I is found in an elderly woman with cardiac disease, caution should be exercised in interpreting the result as indicating that thyrotoxicosis is the cause of the cardiac disorder. Estimation of total T3, FT3I, or free T3 seems useful in confirming euthyroidism in such cases.

Adolescent↗
PubMed1969

Thyroid stimulation test with serum thyroxine concentration as index of thyroid response.

A thyrotropin (T.S.H.) test is suggested which relies on the change in the concentration of serum thyroxine as the index of thyroid response to T.S.H. stimulation. Ten such tests have been carried out in healthy volunteers and 39 in patients referred for routine thyroid stimulation tests. Among the advantages of such a test are that the patient does not receive ionizing radiation; it is independent of the presence of iodide-or mercury-containing compounds; and it minimizes the number of patient visits. In remote areas the patient need not attend the specialist centre, because the T.S.H. injection can be given and the serum samples taken locally, the samples then being sent to the appropriate laboratory for assay.

Adult↗
PubMed1969

Thyroid suppression test with serum thyroxine concentration as index of suppression.

A thyroid suppression test is suggested which relies on the change in concentration of serum thyroxine as the index of thyroid response to the administration of triiodothyronine. The test has been carried out in 16 healthy volunteers and in 27 patients referred for routine suppression tests. This index appears to be sensitive and safe and results in a reduction in the required dosage of triiodothyronine. The test can be carried out in fewer patient-visits than the commonly used suppression test; moreover, in remote areas the patient need not attend the specialist centre because the course of triiodothyronine can be given (and the serum samples obtained) locally, the samples then being sent to the appropriate laboratory for assay.

Adult↗