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Biomedical subjects

S Lurie

Publications and source records attributed to S Lurie.

At least 73 records · Page 4Linked to original sources
PubMed1997

Serum testosterone, DHEAS, and prolactin levels in patients with a Bartholin's abscess.

This study examines Prolactin and Androgen concentrations in 15 women with a Bartholin's gland abscess and in 15 matched normal controls. The Dehydroepiandrosterone sulfate concentrations were higher in the Bartholin's abscess group as compared to the concentrations in the control group [7.0 +/- 3.1 mmol/l versus 4.3 +/- 1.3 mmol/l (p < 0.05), respectively]. The Prolactin and the Testosterone levels did not differ statistically between the two groups.

Abscess↗
PubMed1997

Is it necessary to perform a prophylactic oophorectomy during hysterectomy?

OBJECTIVE: To evaluate the subsequent pelvic sonographic characteristics as well as the clinical outcome following hysterectomy with and without oophorectomy. STUDY DESIGN: A prospective study of sonographic evaluation of 164 women, aged 29-72 years, with a history of hysterectomy was performed. Ninety-one patients underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy and 73 women had either hysterectomy (abdominal or vaginal) only or hysterectomy with unilateral salpingo-oophorectomy. RESULTS: The mean time interval between surgery and sonographic evaluation was 4.3 years (range, 1-25 years). Out of the 73 women with left ovaries, 37 (50.7%) were found to have pelvic lesions and four women underwent re-operations following these findings. The histologic finding were cystadenoma, hydrosalpinx with periovarian adhesions and two paraovarian cysts. In comparison, only five of the 91 women (5.5%) following bilateral salpingo-oophorectomy were found to have pelvic lesions (P < 0.0005). None of the women with prophylactic oophorectomy were operated upon following these findings. CONCLUSIONS: In comparison to patients after total hysterectomy and bilateral salpingo-oophorectomy, women with prior hysterectomy and ovarian preservation are prone to subsequent pelvic lesions. They need to be closely followed with clinical, laboratory and sonographic means, and may undergo reoperations in order to rule out the possibility of neoplasia.

Adult↗
PubMed1997

Isolated persistent fetal bradycardia in complete A-V block: a conservative approach is appropriate. A case report and a review of the literature.

Persistent fetal bradycardia is rarely encountered during pregnancy. When it is associated with a complete atrio-ventricular (A-V) block, it may prove dangerous to the fetus or newborn. The prenatal diagnosis is vital because it necessitates close follow-up during pregnancy to detect fetal compromise and proper preparation for delivery. We describe a woman who was found to be suffering from systemic lupus erythematosus during pregnancy. The fetus was diagnosed as having persistent fetal bradycardia due to complete A-V block at 28 weeks of gestation and was delivered at term with conservative management. The problems entailed in managing pregnancy and delivery of such fetuses are discussed.

Adult↗
PubMed1997

Clinical evaluation of a new model of a transcutaneous electrical nerve stimulation device for the management of primary dysmenorrhea.

Transcutaneous electrical nerve stimulation (TENS) has been proven effective in pain relief of primary dysmenorrhea (PD). We evaluated the efficacy of a new TENS device (Freelady, Life Care, Tiberias, Israel), designed to correct disadvantages of older models used in previous studies, in 102 nulliparous women with PD, who were treated with various types of pain relief medications. Marked pain relief was reported by 58 patients (56.9%) and moderate relief by 31 (30.4%). These subjective findings were supported by the fact that the same number of patients (58 and 31) either stopped analgesic use altogether during the trial or reduced the quantity of analgesics, respectively. The device examined proved to be efficient and safe in controlling the pain and disability caused by PD.

Adolescent↗
PubMed1997

Sigmoid volvulus after medical management with subsequent operative laparoscopy of unruptured ectopic pregnancy.

The use of methotrexate (MTX) as a first-line treatment of ectopic pregnancies has become popular recently. This report details a previously unreported complication of MTX treatment. Presumptive ectopic pregnancy with an initial beta-hCG level of 3,500 mIU/ml was treated with a single intramuscular dose of 50 mg/m2 MTX. Three weeks later with a beta-hCG level of 870 mIU/ml, the patient was operated for suspected rupture of ectopic pregnancy. Laparotomy revealed left aborted tubal pregnancy with active bleeding from left fimbria and estimated 2,000 ml of blood in the cul-de-sac. Left salpingectomy was performed. Two days later the patient developed signs of large bowel obstruction. The second laparotomy revealed sigmoid volvulus, that was treated with detorsion of the sigmoid loop. Although generally safe and effective, MTX should be used with utmost care in treatment of ectopic pregnancies.

Adult↗
PubMed1997

Parathyroid hormone levels in preterm and term labor.

This prospective study was undertaken to test the hypothesis that parathyroid hormone (PTH) might be involved in preterm or term labor. Four groups of patients were formed, 15 patients in each group. The preterm labor group were patients who were admitted to our perinatal care unit with preterm labor and unruptured membranes (< 35 weeks' gestation). The preterm or term nonlabor control groups were patients matched for gestational age, maternal age, and parity, who were not in labor. The term labor group were patients matched for maternal age and parity who were in active labor. Mean (+/-SD) level of biologically intact PTH was 18.9 +/- 10.6 pgr/mL, 7.6 +/- 4.7 pgr/mL, 20.8 +/- 10.1 pgr/mL, 13.7 +/- 5.3 pgr/mL in preterm labor group, preterm nonlabor group, term labor group, and term nonlabor group, respectively (p < 0.05). No statistically significant differences were observed in the levels of calcium, phosphorus, magnesium, or albumin. We therefore suggest that PTH may have a role in preterm or term labor. The nature of its role should be investigated in further studies.

Calcium↗
PubMed1996

Density distribution of erythrocytes in class A2 (insulin requiring) gestational diabetes.

We evaluated the age distribution of erythrocytes in pregnancy complicated by gestational diabetes class A2 by the density distribution of cells (DDC) method. The values for normal pregnancy and nonpregnant women were obtained from recently published studies. The cumulative density distribution of cells (DDC) of women with gestational diabetes resembled that of normal pregnancy.

Adult↗
PubMed1996

Comparison of age distribution of umbilical cord erythrocytes in preeclampsia versus uncomplicated pregnancy.

OBJECTIVE: To evaluate the age distribution of umbilical cord (fetal) erythrocytes in preeclamptic women. METHODS: Prospective evaluation of density distribution of erythrocytes was performed using the density distribution of cells method. Ten consecutive patients having preeclampsia in the third trimester and ten matched controls were studied. Maternal blood samples were taken during the latent phase of labor. Umbilical cord samples were taken immediately after the umbilical cord was cut. An additional control group that consisted of nonpregnant women (n = 30) was determined from our previously published studies. RESULTS: The erythrocyte population of umbilical cord blood of preeclamptic women has a younger age distribution than the erythrocyte population of umbilical cord blood of women with a normal pregnancy. CONCLUSION: The shift in age distribution of erythrocytes in umbilical cord blood of preeclamptic women could be attributed to a shorter life span of erythrocytes compared with that of uncomplicated pregnancy.

Adult↗
PubMed1996

Induction of labor at 38 to 39 weeks of gestation reduces the incidence of shoulder dystocia in gestational diabetic patients class A2.

The purpose of this study was to test the hypothesis that the incidence of shoulder dystocia could be reduced in insulin-requiring diabetic women by elective induction of labor at 38 to 39 weeks of gestation. A prospective study protocol in which labor was induced at 38 to 39 weeks of gestation in insulin-requiring diabetic women was executed between January 1, 1990, and July 31, 1994 (n = 96). The outcome was compared to the results of a previous protocol (years 1983 to 1989) in which the pregnancies were allowed to progress to spontaneous labor, unless fetal health became compromised (n = 164). The incidence of shoulder dystocia in patients in whom labor was electively induced at 38 to 39 weeks of gestation was 1.4% as compared to 10.2% in patients who delivered beyond 40 weeks' gestation (p < 0.05). No increase in cesarean section rate was demonstrated. We conclude that elective induction of labor is suggested for insulin-requiring diabetic women in order to reduce the incidence of shoulder dystocia.

Adult↗
PubMed1996

Fetal oximetry monitoring: a new wonder or another mirage?

This review provides recent data and clinical opinions on a new technology in assessing fetal well-being during labor, the fetal pulse oximeter. Fetal pulse oximetry is potentially superior to electronic fetal heart rate monitoring because it allows direct assessment of both fetal oxygen status and fetal tissue perfusion. Several studies during recent years have demonstrated that fetal pulse oximetry during labor is feasible and accurate. On the other hand, these very same studies have demonstrated a few potential disadvantages and limitations of fetal oximetry. The main limitation seems to be a wide range of normal values. The correlation of fetal oximetry during labor with perinatal outcome and long-term newborn outcome has not yet been determined. In summary, fetal pulse oximetry during labor merits further randomized prospective studies, especially with regard to improvement of perinatal outcome.

Bias↗
PubMed1996

The correlation between heat-shock protein accumulation and persistence and chilling tolerance in tomato fruit.

Heating tomato fruit (Lycoperiscon esculentum) for 48 h at 38 degrees C prevented chilling injury from developing after 21 d at 2 degrees C, whereas unheated fruit developed high levels of injury. Although the overall protein pattern as seen by Coomassie blue staining was similar from heated and unheated fruit, some high- and many low-molecular-mass proteins were observed in the heated fruit that were absent or present in reduced amounts in unheated fruit. When fruit wer injected with [35S]methionine at harvest and then heated, they accumulated high levels of specific radiolabeled proteins that could still be detected after 21 d at 2 degrees C. If the fruit were held at 20 degrees C after heating, the label in the proteins declined rapidly and these fruit were also sensitive to chilling injury. Hsp70 antibody reacted more strongly with proteins from heated and chilled fruit than with proteins from chilled fruit. Hsp18.1 antibody reacted strongly with proteins from heated fruit but not with those from unheated fruit. A 23-kD protein, highly labeled in heated fruit but not in unheated fruit, had its amino terminus sequenced. To our knowledge, this is the first report showing a relationship between the persistence of heat-shock proteins and chilling tolerance in a plant tissue.

Acclimatization↗