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Biomedical subjects

S Lippmann

Publications and source records attributed to S Lippmann.

At least 55 records · Page 3Linked to original sources
PubMed1985

Acutely psychotic patients: a treatment approach.

Treating acute psychosis by rapidly producing a neuroleptic state is safe and effective. Getting psychotic patients quickly out of the hospital, keeping them out, and enabling them to function maximally are the treatment goals. Many such patients respond to a trial of lithium therapy; responders are usually better able to work or attend school and to live independently, and they less often show the degree of personality deterioration present in classical schizophrenia. Patients with schizophrenic, schizoaffective disorder, or bipolar illness should receive trial lithium therapy. Responders to lithium treatment are found in all three diagnostic categories.

Acute Disease↗
PubMed1985

Metrizamide myelography risk factors: a pseudopsychiatric case presentation.

A case of neurologic sequelae from intrathecal metrizamide is presented. The patient had a convulsion, became comatose, and transiently developed mutism and hemiparesis, with eventual full recovery. Metrizamide is generally safe, but side effects do occur, and they may require clinical attention and follow-up.

Adult↗
PubMed1984

Some observations on psychiatric research.

Principles of sound research design are too often incompletely applied in scientific investigations. Physicians may fail to evaluate journal articles for quality of research, comparability among studies, and clinical relevance. For many investigators quick publishable experiments take precedence over those with rigorous methods. Clinicians and researchers are becoming more aware of these concerns. Students should be taught the skills necessary to interpret scientific reading. Greater attention should be given to correct research design, and authors should fully explain both the procedures of a study, and its relevance. Fewer published articles and more review papers or commentaries might also stimulate better research quality.

Forecasting↗
PubMed1983

Drug therapy for depression in the elderly.

Depression is common in the geriatric population, but recovery rates are gratifying. Safe treatment requires attention to the effects of aging on pharmacokinetics and close monitoring. Antidepressants are the drugs most commonly used; to the standard tricyclic drugs have now been added a tetracyclic and a triazolopyridine. Monoamine oxidase inhibitors and lithium are second-choice options; a benzodiazepine is not generally required. Dosages should be lower than conventionally prescribed. Side effects of antidepressant drugs are common, the most important being slowing of cardiac conduction times and the most common being anticholinergic manifestations, such as dry mouth and tachycardia. Some of the more recently introduced antidepressants may have more advantageous side-effect profiles than the older agents.

Aged↗
PubMed1983

Toxoplasma encephalitis in Haitian adults with acquired immunodeficiency syndrome: a clinical-pathologic-CT correlation.

The clinical data, histologic findings, and computed tomographic (CT) abnormalities in eight adult Haitians with toxoplasma encephalitis were analyzed retrospectively. Diagnosis was established by identification of Toxoplasma gondii on autopsy in five and brain biopsy in three specimens and subsequently confirmed by the immunoperoxidase method. All these patients, six of whom had been in the United States for 24 months or less, had severe idiopathic immunodeficiency syndrome. All were lymphopenic and six were on treatment for tuberculosis when the toxoplasma encephalitis developed. All patients were studied with CT when they developed an altered mental status and fever associated with seizures and/or focal neurologic deficits. Scans before treatment showed multiple intraparenchymal lesions in seven and a single lesion in the thalamus in one. Ring and/or nodular enhancement of the lesions was found in six and hypodense areas in two. Progression of abnormalities occurred on serial studies. These CT findings that were best shown on axial and coronal thin-section double-dose contrast studies were useful but not diagnostically pathognomonic. In patients with similar clinical presentation CT is recommended to identify focal areas of involvement and to guide brain biopsy or excision so that prompt medical therapy of this often lethal infection can be instituted.

Acquired Immunodeficiency Syndrome↗
PubMed1983

Alcohol abuse and attention deficit disorder.

The prevalence of alcohol abuse among the fathers, and ADD in family members, of 22 adult psychiatric patients with persistent attention deficit disorder was found to be significantly higher than in 20 matched controls. Further research is necessary to determine the reasons for, and clinical implications of, these associations.

Adolescent↗
PubMed1983

Psychiatric presentations of hyperthyroidism.

Hyperthyroidism is often confused with psychiatric illnesses. Undiagnosed hyperthyroidism sometimes results in inappropriate use of psychotropic medications. Delay in therapy markedly worsens the prognosis for recovery, but complications can be prevented by early treatment. Prompt recognition of hyperthyroidism through thyroid function screening is good medical practice in the evaluation of patients with psychiatric symptoms.

Adult↗