Biomedical subjects
Publications and source records attributed to S Liotet.
A study was conducted on 113 contact lens showing fungal colonies. The main genus isolated was Cepohalosporium (59.4 p. cent). Lens contamination is favoured by a major factor: contact lens spoliation, a secondary factor being inadequate contact lens maintenance. This contamination raises an economic problem, as every affected contact lens must be replaced.
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This observation perfectly illustrates the main epidemiological, clinical and biological peculiarities of this parasitic disease. Particularly, as it concerns a tourist who travelled across Africa for a short period of time it is possible to assess the time of exposure to infecting mosquito bites, the maturation period of time as well as the time of clinical incubation. On the other hand the value of the immunological techniques to make the diagnosis of loaiasis as well as the difficulties to treat this affection are stressed upon.
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Most of sicca syndromes are expressed in a modification of specifically lacrimal proteins. These modifications are involving:--perturbations in tears-electrophoresis, residing in a more or less important decrease of one or several lacrimal proteins,--a frequent sinking in rate of total lacrimal proteins,--a slump of antimicrobial property in tears. The electrophoretic modifications could serve for base to biological classification of sicca syndromes.
A study has been carried out on three groups of subjects. The first group, living in the surrounding of Paris, without inflammatory diseases and without local treatments, gives a contamination rate of 3,92%, which is well balanced with yeasts and fungoid growth myceliums. The principal isolated species were: Penicillium, Aspergillus, Candida, Rhodotorula. The second group with local treatment by mercurothiolate natrium was sterile. The third group, whose subjects had nearly a daily cultivation, allows to establish that: -- The conjunctival fungic flora is variable with time, and differ of a eye from the other for a given subject and its continuance is short; -- The subject contamination seems to be different according to the quality of the immune defenses, the less effective showing always yeasts and fungoid growth myceliums, the other ones slightly infected and only with fungoid growth myceliums; -- The contamination rate seems to be directly related to the intensity of the surrounding atmosphere agitation.
Levels of lacrimal proteins, 90% of which are synthetised by the lacrimal gland, normally vary between 2.5 and 6 g/litre. Three fractions migrating towards the anode may be isolated by electrophoresis: 2 prealbumins corresponding to approximately 30% of the proteins, a poorly known group (4 to 12%) and lactotransferrin (40 to 50%). One fraction migrates towards the cathode: lysosyme (25 to 35%). It is also possible to demonstrate a protein profile of tears (albumin less than 200 mg/l, transferrin less than 20 mg, IgA 100 to 200 mg/l, IgG less than 10 mg/l, bacteriolytic activity equivalent to a concentration of lysosome of 4 to 6 g/litre). In pathology, electrophoresis is valuable in the study of dry syndromes and for identification of fluid from a palpebral cyst. The protein profile is of interest above all when the tears are inflammatory.
129 Lincoff sponge's rejection, representing 4,3% of our retinal detachment surgeries during 4 years have been studied. Men were twice more than women, the larger the amount of material was placed the more frequent rejections appeared. Most rejections (56,2%) occured during the first 4 months. Percentage of infection was roughly not influenced by the time after retinal detachment surgery.
In spite of the similarity between hairs and eyelashes the later shows several physiological and anatomical particularities. We performed an ultrastructural study of eyelashes and reviewed their pathology.
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