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S Liotet

Publications and source records attributed to S Liotet.

At least 37 records · Page 2Linked to original sources
PubMed1987

An interesting use of the study of tear ferning patterns in contactology.

A study of tear ferning patterns in normal and keratoconjunctivitis sicca eyes led to the classification into 4 types by Rolando [1984]. We practised this in our laboratory and observed specific and distinct tear ferning patterns for electrophoretic types 1 and 2 which Liotet et al. [1983] described as abnormal tear proteins modification found in patients who repeatedly and rapidly clog their hydrophilic lenses. In a general way, a study of tear ferning patterns can result in an appreciation of tear quality in contactology.

Contact Lenses↗
PubMed1987

A new hypothesis on tear film stability.

Classically, the stability of the lacrimal film is due to the surfacing of the epithelial surface by the mucus produced by the goblet cells. However, there are many objections to this hypothesis. Deducing from electron microscopy of the epithelial cells, which shows vesicles in the superficial layer and glycocalix threads on the microvilli and other clinical facts, we think that the surfacing agent is not mucus but glycocalix. The disappearance of goblet cells during sicca syndrome is not the cause but the result of the dryness. Epithelial cell integrity is essential for the stability of the tear film and therapeutics must aim at regenerating these cells rather than only replacing the lacrimal film by tear substitute.

Conjunctiva↗
PubMed1987

[Importance of the assay of T3 and T4 tears and plasma for the diagnosis of endocrine exophthalmos].

In the control subject, the thyroidal hormones have been found to be always present in similar quantities in both eyes tears. The proportion of T3 is much more important in the tears (23-40%) than in the plasma (1-2%). It is close to the concentration of deiodinated T4 found in many tissues. In ocular tissues, the T3 is thus very little or even not broken down. This led us to define the tear plasma relationship parameters. We studied lacrimo-plasmatic thyroidal parameters in cases with thyroidal dysfunction without ocular affection: 3 cases of hyperthyroidism, and 2 of hypothyroidism, to study modifications in case of endocrinal problems only. We also studied various types of exophthalmos: 31 cases of endocrine exophthalmos, whether the thyroidal plasma values were normal or not, and 2 cases of exophthalmia with expansive orbital hyperplasia in which there had been no previous thyroidal disturbance. An exophthalmia patient studied, including those with expansive orbital tissue, important changes, specific enough were associated in the tear/plasma parameters, correlated with the changes in the retro-orbital muscular tissues or fat detected by scanning. The study of these parameters, lacrimal thyroid is thus interesting for the diagnosis of endocrine exophthalmos and shows that only a local modification of the metabolism of T3 and T4, mainly from deiodination , process is probably implied in the pathology of these exophthalmos.

Adult↗
PubMed1986

Ultrastructural study of the lacrimal gland in a case of Sjögren's syndrome.

A 78-year-old woman, affected by a Gougerot-Sjögren's syndrome, had a typical keratoconjunctivitis sicca associated with xerostomia. A biopsy of lacrimal and accessory salivary glands was studied by conventional histological methods. In addition, the lacrimal gland was studied by electron microscopy. The two varieties of gland showed lesions of the same intensity with a similar decrease of lactoferrin and lysozyme. However, the ultrastructural features noted in the lacrimal gland were suggestive of an immunological reaction different from that noted in salivary glands. The attrition of ductal epithelia by lymphocytes was obvious but was never followed by regeneration and ductal ectasia. The massive infiltration of lymphocytes in the lobules and the early sclerosis of gland tissue appeared to be the main factor. Apparently, the sclerosis was not consecutive to the activity of periductal myoepithelial cells but resulted from the activity of fibroblasts in the production of basal membranes and collagen connective tissue.

Aged↗
PubMed1985

[Comparative cytological study of conjunctival secretions and smears].

Conjunctival cytology is a part of the biological investigations of conjunctivitis. The actual diagnostic interest of this examination has been evalued in 200 cases. The conclusion of this study is that the direct microscopic examination of conjunctival secretions is simple, fast, inexpensive, very useful, and may be indispensable, in the presence of every type of conjunctivitis. On the other hand, cytologic examination of conjunctival scrapings is of a little interest and its indication must be restricted to a limited number of cases according to the clinical context.

Conjunctiva↗
PubMed1984

Study of the human blood-tear barrier and the biochemical changes in the tears of 30 contact lens wearers (50 eyes).

50 eyes were fitted with contact lenses of different materials. The tears were taken from different surgical departments specializing in the fitting of contact lenses. The tears were analyzed by electrophoresis. Albumin, and filtered and synthesized IgG were assayed in order to find out whether there is a modification in the permeability of the blood-tear barrier in individuals wearing contact lenses. In 40% (A2, B2 b + d) of the cases there were modifications in the permeability of the barrier and in 84% (group A2 + B2 b + c + d), the tears were found to be pathological.

Albumins↗
PubMed1984

[Antibiotic therapy in ophthalmology].

Eye drops containing antibiotics are more and more numerous, we prescribe them more and more frequently. We found it interesting first to gather in six lists all antibiotics used locally in ophthalmology and to study for everyone its bacterial spectrum. After that we see which bacteria are most frequently met by ophthalmologists and when (presurgery examination, conjunctivitis, blepharitis, chalazion, meibomianitis, sty, corneal ulcer, lens infection). All this helps the ophthalmologist to choose the antibiotic he prescribes before the bacteriological specimen, with high confidence. At last, we sum up the little that is presently known about penetration of antibiotics into the eye.

Adult↗