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Biomedical subjects

S Lindequist

Publications and source records attributed to S Lindequist.

At least 19 recordsLinked to original sources

PINTRACE: a computer program for assessment of pin positions in routine radiographs of femoral neck fractures.

A new method for determination of pin positions in internally fixated femoral neck fractures is described. In AP and lateral radiographs of the hip, measurements are made of the cervicofemoral angles, the diameter of the femoral head and neck, and the distances from the central femoral neck axis to each pin. From these values the positions of the fixation pins in defined straight AP and lateral projections are determined by geometric calculations. A computer program in BASIC was developed to perform the calculations and to produce graphic displays of cross-sections of the femoral head and neck with the corrected pin positions indicated. For routine radiographic examinations with unknown inclination angles of the X-ray beams, the error of the method is less than 5% of the femoral head diameter. With conventional methods of determining pin positions the error can exceed 25% of the femoral head diameter.

Algorithms

Granulocyte adherence after intravenous and intraarterial injection of ioxaglate or iohexol.

The effect of iohexol and ioxaglate on granulocyte adherence to nylon fibers was investigated with blood from 15 patients undergoing angiography, and from 24 patients undergoing excretory urography. Decreased adherence and increased numbers of granulocytes in the circulation were observed soon after injection of iohexol or ioxaglate in the aorta, or injection of ioxaglate i.v. Increased adherence and decreased numbers of granulocytes in the circulation were observed soon after injection of iohexol i.v. The differences were small soon after the injection of contrast media (CM). More pronounced decreased adherence and increased numbers of granulocytes were detected 2 and 5 hours after injection in the aorta for both CM.

Aorta

Lack of correlation between ulnar variance and carpal bone angles on lateral radiographs in normal wrists.

It has been proposed that negative ulnar variance is a predisposing factor to development of posttraumatic carpal ligamentous instability. However, this implies that no correlation exists between ulnar variance and carpal bone angles in the normal wrist. Carpal bone angles on lateral wrist radiographs and ulnar variance were measured in a series of 75 normal wrists. The mean ulnar variance was -0.03 mm (SD 1.56, range -5 to 5). The correlation coefficients were 0.06, -0.11, and -0.05 between the ulnar variance, and radiolunate, radioscaphoid, and scapholunate angles, respectively. A correlation between the carpal angles on lateral wrist radiographs, and ulnar variance in normal wrists could not be demonstrated, suggesting that the presence of negative ulnar variance may serve as an impartial clue to the presence of ligamentous instability.

Adult

Measurements of carpal bone angles on lateral wrist radiographs.

Measurements of carpal bone angles on lateral wrist radiographs can be of assistance in the diagnostic evaluation of wrist malalignment. A series of 75 normal wrists was examined by use of a standardized radiographic technique. The normal carpal bone angles were determined using the bone axes with the least observer variability (mean and range): radiolunate, -1.02 (-10 to 12), radioscaphoid, 51.80 (35 to 65), and scapholunate, 50.77 (36 to 66). Normal mean values and ranges for intercarpal bone angles may be of assistance in the diagnostic evaluation of ligamentous injury to the wrist.

Adult

Observer variability in measurements of carpal bone angles on lateral wrist radiographs.

Determinations of carpal bone angles are used in the clinical evaluation of carpal malalignment. Eleven frequently referred radiological measures in lateral projection of the wrists in 23 wrists were assessed using different definitions of axes. Interobserver- and intraobserver variations were calculated. The standard deviation of the interobserver variation ranged from 2.60 degrees to 18.15 degrees, and the intraobserver variation from 1.89 degrees to 4.66 degrees depending on the angles measured. The use of three angles for the least observer variability in assessment of carpal alignment is recommended. These angles were defined from the following carpal bone axes: radius, the line through the center of the medullary canal at 2 cm and 5 cm proximal to the radiocarpal joint; lunate, the line perpendicular to the tangent of the two distal poles; scaphoid, the tangent of the palmar proximal and distal margins, and capitate, the tangent of the dorsal margin of the diaphysis of the third metacarpal bone (substitute axis).

Adult

Diagnostic quality and complications of hysterosalpingography: oil- versus water-soluble contrast media--a randomized prospective study.

In a prospective randomized study of 417 patients, side effects and complications of contrast media and the diagnostic quality of images obtained after hysterosalpingography (HSG) were evaluated after use of diatrizoate meglumine (104 patients), ioxaglate (105 patients), iohexol (105 patients), or ethiodized poppy-seed oil (103 patients). The authors detected no differences among these groups in the prevalence of pain during HSG. The prevalence of lower abdominal pain and vaginal bleeding after HSG was significantly lower in the group that received ethiodized poppy-seed oil than in the three other groups. The prevalence of pelvic infection or inflammation was significantly lower with ethiodized poppy-seed oil than with water-soluble media. All contrast media provided acceptable diagnostic image quality with regard to fallopian tubes, peritoneal spill, and intraperitoneal distribution. Visualization of the uterine cavity and ampullary rugae was significantly better with water-soluble media than with ethiodized poppy-seed oil, which was associated with a high conception rate and which the authors consider preferable for HSG.

Contrast Media

Therapeutic effect of hysterosalpingography: oil- versus water-soluble contrast media--a randomized prospective study.

In a prospective randomized study, the number of pregnancies after hysterosalpingography (HSG) was estimated in 398 patients who had been infertile for longer than 1 year. Iohexol was used in 101 patients, ioxaglate in 102 patients, diatrizoate meglumine in 97 patients, and ethiodized poppy-seed oil in 98 patients. Ten months after HSG, the patient, referring physician, and/or hospital department was consulted for information about pregnancies. Questionnaires were obtained from the patients who became pregnant during the waiting period of 3 months. No differences in demographic parameters, infertility status, or diagnosis made with HSG were detected among the four contrast media groups. Significantly more patients became pregnant after HSG in the ethiodized poppy-seed oil group than in the three water-soluble contrast media groups (P less than .01). When only intrauterine pregnancies resulting in full-term births were considered, significant differences in pregnancy rates between the oil-soluble and the water-soluble contrast media groups became more obvious. In the group that received ethiodized poppy-seed oil, almost one-third of the infertile women had normal pregnancies and childbirths after HSG.

Contrast Media

Fractures of the proximal humerus in children. Nine-year follow-up of 64 unoperated on cases.

Fracture of the proximal humerus in children is rare. The records from 1976 to 1977 of 77 patients aged 0-15 years with a fracture or epiphyseal separation of the proximal humerus were reviewed. Totally, 64 of 72 patients had a follow-up examination (median observation time 9 years). Twenty-one children had an epiphyseal separation and 51 a metaphyseal fracture. All but 1 were treated conservatively. Seven had slight sequelae at follow-up, i.e., transient pain or minor restriction of motion. The rest were asymptomatic. Full remodeling of fractures left displaced occurred in all the cases. No avascular necrosis or shortening of the humerus were found. Nonoperative treatment is appropriate for proximal humeral fractures in children, even for those with extensive displacement.

Adolescent

Ultrasound guided needle biopsy of skeletal muscle in neuromuscular disease.

Guided by ultrasonography percutaneous needle biopsy of skeletal muscle was performed in 24 patients, using the one hand held Biopty system and a 2 mm Tru-Cut needle. The specimens were graded with regard to diagnostic quality and utility and almost all specimens (96%) were of highest quality. The use of ultrasonography was helpful in selecting a suitable area for the biopsy and vascular structures could be avoided. The procedure was well tolerated and easy to perform, and no complications were recorded.

Adult

Radiography of the wrist. A new device for standardized radiographs.

A number of methods exist for determination of carpal bone angles on lateral wrist radiographs. However, there is no general or precise definition of the angles measured. In this study the positioning of the wrist is emphasized and a device used to obtain standardized radiographs is presented. An analysis of variance of two series of patients revealed no radiological difference between the contralateral wrists in the same person. We conclude that the asymptomatic wrist can be used as normal reference in the assessment of carpal bone angles in the pathological wrist and a difference between the carpal bone angles in the two wrists in the same person exceeding 5 degrees can be considered significant.

Adult

Intussusception in children: plain abdominal radiograph and reduction by barium enema in relation to clinical features.

A retrospective study of 98 patients representing 104 instances of intussusception is reviewed. Criteria for inclusion in the study were: the patients primary admitted to the department of diagnostic radiology, plain abdominal radiographs performed prior to barium enema (BE) and/or surgery and diagnosis confirmed by BE or surgery. A success rate of BE reduction of 58.6% was achieved. The clinical features are described and the value of plain abdominal radiograph in ruling out the diagnosis of intussusception is discussed.

Barium Sulfate

Bone grafting in femoral neck fractures: results in 28 cases operated on with multiple pinning and cancellous bone grafting.

Twenty-eight patients with displaced femoral neck fractures were operated on with multiple pinning combined with cancellous bone grafting from the ipsilateral greater trochanter. The bone graft was introduced through a drilled channel in the femoral neck without exposing the fracture. At follow-up after 2 years, seven patients had died. Two patients had been reoperated with prosthetic replacement of the hip. Nineteen fractures were united and one had developed segmental collapse. In femoral neck fractures, complications from non-union and segmental collapse are still a major problem. Even if the impaired vascular supply to the femoral head is responsible for most of the complications, anatomic reduction and a stable fixation are conductive to fracture union. Comminution of the posterior wall of the femoral neck has a negative influence on the security of fixation due to a persisting posterior gap after reduction. In previous reports, bone grafting of the posterior defect in the femoral neck through an open approach has achieved good results. Only a few studies, however, describe a technique of introducing bone chips through a drilled channel in the femoral neck. The use of the ipsilateral greater trochanter as the sole donor site for bone grafting in femoral neck fractures has not been reported previously.

Aged

Treatment of solitary enchondromas in fingers.

The results after operative treatment of 21 solitary enchondromas of finger bones are described. 15 cases were treated by curettage and cancellous bone grafting, five by curettage alone, and one with amputation. One case did not heal after curettage and grafting. When symptoms are present or the cortical strength is decreased, we recommend operation. We find that the eccentric type of enchondroma can be treated adequately by curettage alone, while curettage and filling of the cavity with cancellous bone should be preferred in the central and polycentric forms. It is important that all material is removed from the cyst, which has to be packed completely with bone chips. The possibility of malignant change in enchondromas should be borne in mind, but we did not see this.

Adolescent

Fixation of femoral neck fracture. Prospective comparison of von Bahr screws, Gouffon screws, and Hessel pins.

We report a prospective study of 214 patients with femoral neck fractures operated on with multiple pinning. The fractures were randomly allocated to fixation with either von Bahr screws or Hessel pins in 1983 and 1984 or von Bahr or Gouffon screws in 1984 and 1985. After 2 years, the failure rate was one third in the von Bahr and the Gouffon screw groups and one half in the Hessel pin group. We conclude that the nonthreaded Hessel pin is inferior to the von Bahr and Gouffon screws for fixation of femoral neck fractures.

Adult

Computerised tomography after posterior dislocation of the hip.

We have reviewed 19 consecutive patients admitted to the Odense University Hospital after traumatic dislocation of the hip. We aimed to perform computerised tomography as soon as possible after closed reduction; this was accomplished in 15 patients. The CT scans revealed intra-articular fragments of bone in five hips, and fractures of the femoral head or acetabulum in six. In two cases the CT scans excluded fractures or intra-articular fragments which had been suspected on conventional radiography. CT scanning is a useful diagnostic tool in traumatic dislocation of the hip; we consider that it makes an important contribution to management.

Acetabulum