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Biomedical subjects

S Limon

Publications and source records attributed to S Limon.

At least 37 records · Page 2Linked to original sources
PubMed1985

[Behçet's disease: a vascular function study by the venostasis test and DDAVP infusion].

Recurrent thromboembolic accidents are frequent complications of Behçet's disease. Ten patients were investigated, 5 of them during an acute exacerbation of the disease. Abnormal responses to the venostasis test and to DDAVP (i.v.) were demonstrated in acute cases. Factor VIII activities after DDAVP were increased in all 10 patients, which suggests that the response of the vascular endothelium to the stimulus was normal and that a fibrinolytic system inhibitor may be present in the plasma of some patients.

Adolescent↗
PubMed1985

[Current aspects of the Vogt-Koyanagi-Harada syndrome. Apropos of 9 cases].

We have studied 9 cases of the Vogt Koyanagi Harada (VKH) syndrome as defined by the criteria of the American Uveitis Society; all these cases presented evidence of past or present exudative retinal detachment (RD). In 2 cases the RD was shallow and limited to the posterior pole, in 3 cases encephalo-meningeal symptoms were absent, in 2 cases skin and hair symptoms were absent. In all, 5 cases in this series presented as an incomplete, dissociated form of the disease. However the clinical cause of the disease in these "formes frustes" was not simpler or quieter than in the complete forms; incomplete response or drug dependence were encountered with steroid therapy, and immunosuppressive drugs were used in 3 cases. It is to be noted that in one case an extensive RD involving the posterior pole occurred bilaterally: this RD did not respond to maximal steroid and immunosuppressive therapy and reattachment was obtained only after vitrectomy. In another case bilateral optic disc neovascularization was observed in association with severe papillitis despite heavy steroid therapy. A cure was obtained with immunosuppressive drugs.

Adolescent↗
PubMed1984

[Allergic granulomatous nodule of the conjunctiva].

Six cases of conjunctival allergic granulomatous nodules are reported. This benign lesion was described by Ashton and Cook in 1979. It is commonest in children and young people. Clinically it consists of one or more raised yellow nodules beneath the epithelium of the bulbar conjunctiva. Histologically these nodules consist of an amorphous eosinophilic material surrounded by epithelioid and giant cells arranged in a palisade; often some eosinophils are found in the inflammatory reaction. In the absence of surgical intervention these lesions can disappear spontaneously or after corticotherapy in a few weeks or months. According to Ashton and Cook these granulomas show the histologic feature of the Splendore Hoeppli phenomenon, that is, a giant cell and eosinophilic granulomatous reaction to an antigen-antibody precipitate in relation to parasite or fungi. In two cases Ashton and Cook found fragments of nematode larvae but usually no foreign bodies or parasites are identified in the lesions.

Antigen-Antibody Complex↗