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Biomedical subjects

S Lewis

Publications and source records attributed to S Lewis.

At least 433 records · Page 24Linked to original sources
PubMed1979

The greening of the Meadows.

When bulldozers flatten old-established terraces and people are forced to move miles across a city, community spirit all too often gets demolished in the process. But in a South Nottingham clearance area the neighbourhood ties have survived the upheaval and have led to the placing of not just a token social worker in a health centre, but an entire social work team.

Community Health Centers↗
PubMed1979

Joint care: chasing the shadow from our most sun-filled days.

With 118,000 people dying of cancers of different kinds in England yearly both the patients and their families need support through this rite de passage period. Sadly, the majority are not receiving the care they need. Author reports on the UK's first district general hospital-based support team for the care of the dying.

Family↗
PubMed1979

Building a care service on rock foundations.

A more comprehensive home care service is to receive the largest portion of Bromley AHA's joint financing allocation. Author looks at the scope of the home care system and Bromley's success in extending the service.

Aged↗
PubMed1979

The time of origin of the mesencephalic trigeminal neurons in Xenopus.

Time of origin of the mesencephalic trigeminal cells (MTC) in Xenopus 'has been studied with 3H-thymidine autoradiography. The first MTC's were formed at stage 20, and they continued to arise up to stage 58. The mitotic rate of MTC's was found to be ten per cent at any time from stages 20--50, with a slow decrease thereafter. MTC's in the tectum were distributed in a spatio-temporal manner. Cells generated earliest were located in the rostral pole of the tectum and were followed in caudomedial sequence by cells formed later. The generation times of MTC and the neurons of the sensory trigeminal ganglion (TGC) were strikingly dissimilar, indicating that they probably do not represent a common cell lineage, that is, the former may not arise from the mesencephalic neural crest. It is proposed that the majority of MTC's generated from stage 30 onward, derive through proliferative activity of precursor cells in the di-mesencephalic junction and in the tectal neuroepithelium.

Age Factors↗
PubMed1979

Characteristics of the washout dead space.

The dead space volume was reproducibly measured in normal and diseased lungs by analysis of an inert gas washout. This washout dead space was appreciably larger than that measured by the Fowler technique. In the patients, the washout dead space (VD(0)) formed 72% of the physiological dead space volume, while the Fowler (VD(F)) method accounted for only 50%. The VD(O) increased significantly with age in males, but not in females. VD(F) was not well related to age in this population. VD(O) and VD(F) did not relate to lung volume in these subjects. Although that portion of the dead space delivered in Phase I was significantly greater in males than in females, it was not responsible for the difference in dead space measured by the two techniques. This volume difference was found in that portion delivered late in the breath (Phase III). The nature of this volume is speculative, but may involve a parallel dead space that is measured in addition to the series dead space.

Adult↗
PubMed1979

Relation between cognitive and motor-oriented systems of visual position perception.

Although subjects failed to detect a target displacement if it occurred near the time of a saccadic eye movement (a cognitive visual task), they were still able to point to the center of the target with an unseen pointer (a motor visual task). Pointing performance was not affected by detecting or failing to detect a stimulus displacement. The experiments demonstrate that some information that is available to a motor-oriented visual system is unavailable to the cognitive visual system, under conditions simulating normal perception.

Cognition↗
PubMed1979

The use of Technetium-99m stannous pyrophosphate scintigraphy to identify muscle damage in acute electric burns.

High-voltage electric burns are often associated with deep muscle damage in addition to a limited cutaneous burn. Technetium-99m stannous pyrophosphate (99mTc-PYP) scintigrams were evaluated as a diagnostic tool to detect and localize both large and focal areas of skeletal muscle necrosis. Scintigrams were performed in 14 patients between the first and fifth postinjury days and imaging was done over areas of suspected and clinically apparent muscle injury. Muscle damage was identified by an increased cellular uptake of the tagged material. All 14 patients had gross and histologic evidence of muscle necrosis. Muscle necrosis was identified as early as 24 hours and as late as 6 days postinjury. The location and extent of muscle injury was correctly ascertained preoperatively in all patients.

Burns, Electric↗
PubMed1979

Renal hyperconcentration of 99mTc-HEDP in experimental acute tubular necrosis.

The effect of transient renal ischemia on renal concentration and distribution of 99mTc-HEDP, 99mTc-DMSA, and 99mTc-DTPA was compared in rabbits with acute tubular necrosis. Scintigrams were obtained after injection in normal rabbits or ones with unilateral or bilateral ischemia. 99mTc-HEDP concentration in ischemic tissue was 8 to 18 times normal 1--4 hours after injection, and the resulting images delineated the morphological changes in the ischemic kidneys more accurately than those obtained with DMSA or DTPA. Calcium concentration in the ischemic kidneys increased sixfold. 99mTc-HEDP may be useful in evaluation of renal failure secondary to tubular injury.

Acute Kidney Injury↗
PubMed1979

Comparison of interlaboratory results for blood lead with results from a definitive method.

Results reported by 113 participants in the Blood Lead Proficiency Testing Program conducted by the Center for Disease Control were compared with those obtained by the National Bureau of Standards (NBS) with a definitive methods (mass spectroscopy-isotopic dilution) for blood lead analyses. Data were compiled from the results obtained for 12 whole-blood samples containing 1.5 g of disodium EDTA per liter. Twelve separate blood samples were obtained from cattle which had been given lead nitrate orally. Lead concentrations in the samples ranged from 0.628 to 4.93 mumol/L (130-1020 micrograms/L) as determined by NBS. The methods used by laboratories were classified according to six basic groups: anodic stripping voltametry; and atomic absorption spectroscopy in which either extraction, carbon rod, graphite furnace, tantalum strip, or Delves cup was used. For results obtained in each group a linear regression analyses of laboratory values was made on the basis of NBS values. In comparison to the definitive method, most field methods for blood lead tended to overestimate the lead concentration when the actual lead concentration was less than 1.96 mumol/L (400 micrograms/L) and to underestimate the lead concentration when the actual lead concentration was greater than 2.45 mumol/L (500 micrograms/L).

Humans↗