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Biomedical subjects

S Levine

Publications and source records attributed to S Levine.

At least 721 records · Page 40Linked to original sources

Maternal and environmental influences on the adrenocortical response to stress in weanling rats.

Handling rat pups either for 10 or 20 days after birth resulted in a reduction of adrenocortical steroids in the plasma at weaning after the pups were exposed to novel stimuli as compared with controls that were not handled. Nonhandled offspring of mothers which had been handled in infancy also show a reduction in plasma steroids in response to novel stimuli when compared to nonhandled weanling rats of nonhandled mothers. Handling of the offspring when they are infants appears to counteract the influence of the experience of the mother during her infancy.

Adrenal Glands↗

Adrenocortical influences on free-operant avoidance behavior.

Rats were conditioned to avoid shock on a free-operant avoidance schedule in which no exteroceptive stimulus signaled impending shock. Injections of adrenocorticotropic hormone (ACTH) or dexamethasone raised blood levels of glucocorticoids. These increases were accompanied by changes in avoidance performance: there was a higher frequency of long-duration interresponse times, a greater stability among them, and fewer short interresponse times, total responses, and shocks.

Adrenocorticotropic Hormone↗