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Biomedical subjects

S Levi

Publications and source records attributed to S Levi.

At least 163 records · Page 9Linked to original sources

Failure of trimethoprim-sulfamethoxazole in the therapy of recurrent Pneumocystis carinii pneumonia.

The use of trimethoprim-sulfamethoxazole in the treatment and prophylaxis of Pneumocystis cariniii is well established. Treatment failure with this regimen has been ascribed to inadequate antibiotic serum concentrations. We describe an immunosuppressed patient with recurrent Pneumocystis carinii pneumonia who failed to respond to trimethoprim-sulfamethoxazole therapy despite high antibiotic serum concentrations. Subsequently, a response to pentamidine isethionate was obtained. The reason for failure and therapeutic implications in patients with Pneumocystis carini pneumonia who have received trimethoprim-sulfamethoxazole are discussed.

Child↗

Anemia of pregnancy: evaluation of the effectiveness of routine dietary supplementation program in an Israeli community.

Of 514 Israeli women 4-5 months pregnant, 200 who were non-anemic (Hb 11 gm/100 ml or higher) took a daily supplement of ferrous sulfate (100 mg elemental iron). The 160 who remained on this regimen showed, as a group significantly less reduction in hemoglobin levels than 180 non-anemic women who did not wish to take the supplement. Forty of the 200 women either dropped out or were shifted to other treatment regimens because they developed anemia after the fifth month.

Adolescent↗

The AAS determination of copper and zinc levels in the serum of hemodialysis patients.

An electrothermal atomic absorption technique for the determination of subnanogram amounts of copper and zinc in aqueous and blood serum matrices has been evaluated. The technique has been utilized to study the effect of dialysis (artificial kidney) on the levels of these trace elements in the serum of hemodialysis patients. The present results confirm a previous study (1) which was conducted on representative samples that were taken from the continuous flow of the dialysis fluid (dialysate). Matrix effects have been minimized by using serum controls (obtained from a pool made of the tested serum samples), small sample size, and background correction. Before dialysis, values of copper for patients who were dialysed against tap water (tap-water patients) and distilled water (distilled-water patients) were: (mean +/- SD) 1297 +/- 59 and 1064 +/- 137 micrograms/L, respectively; after dialysis: 1539 +/- 98 and 1120 +/- 129 micrograms/L, respectively. Zinc levels were less affected by the dialysis process; before dialysis: tap-water patients, 952 +/- 131 micrograms/L; distilled-water patients, 932 +/- 119 micrograms/L; after dialysis: 1001 +/- 137 micrograms/L, and 934 +/- 121 micrograms/L, respectively. Because the method is sensitive, accurate, and precise, it can be utilized to study trace levels of copper and zinc in serum when limitations of sample volume exist as in the present case or with pediatric patients.

Copper↗

The diagnostic value of ultrasonography in 342 suspected cases of ectopic pregnancy.

The value of ultrasonography as a diagnostic or screening tool is studied in 342 cases of potential ectopic pregnancy. Ultrasonography was used as a diagnostic technique when the echopattern was clear enough to pose a diagnosis of ectopic or non-ectopic pregnancy, including intra-uterine pregnancy, abortion or other pelvic abnormalities. Diagnosis was possible in 77 per cent of the examined patients, with 95 per cent correct diagnosis, 2 per cent false positives and 3 per cent false negatives. For ultrasonography simply as a screening technique whatever the echopattern might be, i.e. in all cases, 78 per cent were selected correctly, with 20 per cent false positives and 2 per cent false negatives. The high quality of the ultrasonic data, combined with the relative absence of the disadvantages of roentgen-rays and invasive techniques, makes ultrasonography the first examination of choice in cases of clinical suspicion of ectopic pregnancy.

False Negative Reactions↗

Value of ultrasonic diagnosis of gynecological tumors in 370 surgical cases.

Ultrasonic exploration of the female pelvis to confirm or supplement the usual clinical examination enabled a correct diagnosis to be made in 80% of the 370 cases examined and subsequently operated on. The echographic description always included the size of the tumor, tis cystic or solic nature and its site of origin. Out of 43 uterine and ovarian tumors measuring less than 3 cm, only 15 were discovered.

Adenocarcinoma↗

Fragmentation of purified mammalian DNA molecules by ultrasound below human therapeutic doses.

Because of the increasing medical use of ultrasound, especially in obstetrical diagnosis, it has become important to check its genetic harmlessness. Purified calf thymus DNA in solution was exposed to both therapeutic and obstetrical diagnostic doses of ultrasound. Intensities lower than those used in therapy have a drastic effect on purified DNA in solution, although intensities used in obstetrical diagnosis caused no visible effect.

Animals↗

Antenatal fetal growth from the nineteenth week. Ultrasonic study of 12 head and chest dimensions.

Fetal head, chest, and heart cross-sections obtained by ultrasonic diagnostic techniques were used for several measurements: circumference, area, and two diameters, i.e., 3,388 different measurements from 767 healthy fetuses in normal pregnancies. The mean growth for 12 fetal sizes between the nineteenth and the forty-third weeks after the LMP was computed by determining the best adjusted polynomial according to Tchebitcheff. Compared with similar measurements made previously by others on premature neonates, the sizes of healthy fetuses of the same gestational age are larger, but almost identical after the thirty-sixth week. Growth standards based on the sizes of premature neonates may be influenced by the factors responsible for premature birth.

Anthropometry↗