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Biomedical subjects

S Lenk

Publications and source records attributed to S Lenk.

At least 55 records · Page 3Linked to original sources

[Double-balloon urethrography in the female].

76 women with pains in the lower efferent urinary tract were urethrographically examined by the double balloon method according to Davis and Cian. The morphological changes registered were correlated with anamnestic, clinical and urodynamic findings and the following indications were derived for this X-ray examination of the female urethra: differential diagnosis between suburethral tumour and urethral diverticulum, recidive infections of the urinary tract, urethral syndrome, uromanometrically proved functional disturbances in the region of the bladder and urethra, painful catheterism and suspicion of urethrovaginal fistula.

Adult↗

[20 years' treatment of urogenital tuberculosis with reference to the epidemiology and the general tuberculosis situation].

After introductory remarks on the historical development of the treatment of patients with UGT, the general tuberculosis situation in the GDR is referred to. With the steady decline in tuberculosis of the respiratory system, a clear reduction in the rate of new cases of UGT was registered from 1972 on, due to the well-known late manifestation of the disease. In 1980, 164 new cases of urological tuberculosis were registered, which represent a rate of less than 1 (0.97) new case per 100,000 head of population for the first time. It has been possible to reduce the total duration of medicinal treatment to 9 months from an original figure of 2 years. Despite the use of highly effective aggressive anti-tuberculosis agents the rate of nephrectomy in our patients is 27%, whereby in the last 6 years as many as 31% of all patients with UGT have undergone nephrectomy in the course of treatment. In 20 of these 54 patients the nephrectomy had already been performed elsewhere and UGT was diagnosed from histological examination of the surgical specimen. Neglected cases have become more common in the last 6 years. UGT has been diagnosed very late, whereby it has been observed that patients with pronounced tubercular changes have been little affected in their general state of health. In one case urotuberculosis appeared after a kidney allotransplantation from a dead donor.

Adolescent↗

[Diagnosis and therapy of obstructive azoospermia--model of interdisciplinary cooperation in andrology].

An interdisciplinary diagnostic and therapeutic program for treatment of male infertility dueto obstructive azoospermia is presented. Important diagnostic methods are testicular biopsy and vesiculo-deferento-epididymography. The most important and successful operative techniques are discussed and the advantage of microsurgical dissection and reconstruction of the obstructed ductus deferens and epididymis reviewed.

Humans↗

[Diagnosis and therapy of malignant parenchymal kidney tumors].

We think that the present paper insistently demonstrates the fact which is acknowledged by all but followed only by few how important is a unitary classification of the renal tumours in order to perform scientifically proved comparisons and valuations in all branches of the treatment of renal tumours including the results of the therapy. On the basis of the classification of our patients according to the TNM-system we could prove that the best results in the operative removal of the kidney with following irradiation were achieved in the categories T1 and T2, particularly when there were not yet present any metastases distant from the primary tumour.

Adenocarcinoma↗

[Modern therapy and after-care in urogenital tuberculosis].

The present therapy of the urogenital tuberculosis is based on the effective medicaments (rifampizin, isonicotinic acid hydrazid, streptomycin, and ethambutol). It rests on an optimum dosage in connection with a best suited combination, taking into consideration the relations of sensitiveness and side effects as well as consequent long-term treatment. It is referred to the possibility of additional administrations of corticosteroid preparations and it is taken notice to the necessity also to treat unspecific mixed infections. Under the modern chemotherapy with bactericidal effect a stable negativation practically always develops within 3 months. Actual recidivations were not seen during the last 12 years. Apart from a compilation of the indications to nephrectomy references to possibilities of plastic surgical corrections of the urinary system are given. Two tables give information about the patients who were operatively treated during the last 15 years. A close collaboration of the various therapeutic institutions with a consulting urologist -- particularly in problematic and advanced cases of the disease -- nearly always saves the patient with urogenital tuberculosis from invalidism.

Adrenal Cortex Hormones↗

On the therapy of urolithiasis in chronic renal failure.

A resigning attitude in respect to patients suffering from nephrolithiasis and manifest renal failure is not justified anymore in view of the advances in diagnosis and therapy. During the period 1964-1975, at the urological clinic of the hospital Friedrichshain 188 patients suffering from nephrolithiasis and renal failure have been treated: 120 surgically and 68 conservatively. The operative-therapeutical conception is outlined. The pre- and postoperative hemodialysis therapy is described in detail and the different indications of hemodialysis according to the stage of renal failure are elaborated. Tabulated data demonstrate the fate of all surgically treated patients.

Adolescent↗

[Urogenital tuberculosis within the scope of general tuberculosis situation. Ambulatory management and care].

On the basis of two differential graphs the development of the general situation concerning tuberculosis in the GDR for the years 1962 to 1976 is described. Particularly taken into consideration were the new cases of urogenital tuberculosis which were compared with the rates of new cases in other countries. A significantly higher morbidity of tuberculosis was found in members of certain risk groups (so-called "gesunde Befundträger" [healthy persons not yet suffering from tuberculosis]). Regulations of the law for prevention of and combat against tuberculosis, principles of the continued ambulant treatment and the importance of the dispensary care were discussed. The success of treatment in the Berlin district, especially in the combat against urogenital tuberculosis, which refer to a more than 12 years observation period, are traced back to a continuity of initial stay in an urological clinic in connection with special procedures, following continued ambulant treatment and final after-care.

Aftercare↗

[Diagnostic and treatment of prostatic cancer (author's transl)].

The diagnosis of prostatic cancer must be proved by biopsy. Transrectal fine needle biopsy and punch biopsy are also useful methods for the outpatient clinic. Besides X-ray examination scanning angiography and lymphography may be used to identify metastases. Combined antiandrogenic therapy is still the treatment of choice and is based on endocrinologic analysis of testosterone, LH levels and testosterone-binding beta-globulin. Radionuclids (32P, 89Sr) should be used for treating metastases of the bone. Chemotherapeutic substances showed unsatisfactory results. Radical prostatectomy can only be performed in 5 to 10% of all patients with prostatic cancer to metastases in T1 and T2 cases. Since 1965 the radiation therapy (linear accelerator or (60Co-source) gives more hope. We treat patients free from metastases with a 60Co-source (right and left lateral 120-degree arc rotational therapy with 5000 rads over 5 weeks) combined with hormonal therapy. The therapeutic effect is checked by fine needle aspiration biopsy.

Antineoplastic Agents↗