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Biomedical subjects

S L Warren

Publications and source records attributed to S L Warren.

57 records · Page 4Linked to original sources
PubMedDate not supplied

Further studies on the specific infectious agent isolated in rheumatoid arthritis.

The active agent in crude or extracted materials from patients with acute rheumatoid arthritis (RA), when injected into embryonated eggs, produced an increased percentage of characteristic "crooked toe" defects in the bioassay. Experimental RA chick materials also produced these defects. A protein-free ribonucleic acid extract from RA synovia and joint fluids of patients with acute or subacute classical RA produced the same experimental RA lesions as did the crude materials, but non-RA materials and controls did not. The injected RA material produced the "crooked toe" disease in chicks in direct proportion to the clinically diagnosed severity of the RA in the patient, and inversely with dilution.

Acute Disease↗
PubMedDate not supplied

Co-existence of hypertension and abnormal lipid profile: a hospital-based retrospective survey.

Indian data on co-existence of coronary risk factors is scanty. This retrospective survey was carried out to estimate the prevalence of abnormal lipid profile and glucose metabolism in hypertensive patients. Records of persons coming for a health check-up were screened to obtain 500 consecutive evaluable records of persons with hypertension or those taking antihypertensive drugs. 57 percent of these subjects had cholesterol > or = 200 mg/dl. An elevated ratio of total to HDL cholesterol (> 4.5) was also present in 47 percent of the subjects. Serum triglycerides were > or = 200 mg/dl in 34 percent of the subjects, and > or = 400 mg/dl in 5 percent. These lipid abnormalities were more prevalent in males than females (p < 0.05). 20 percent of all the subjects were either on antidiabetic drugs or had fasting blood sugar more than 120 mg/dl.

Antihypertensive Agents↗