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Biomedical subjects

S L Rothman

Publications and source records attributed to S L Rothman.

At least 37 records · Page 2Linked to original sources

Sella 'erosions' in a series of 50 normal women: the place of tomography in the diagnosis of prolactin secreting pituitary microadenoma.

The following paper assesses the results of pluridirectional tomograms in 50 normal females of reproductive age, as reflected by the opinions given by 4 different radiologists with major interest in the pituitary fossa. Only 16 of the 50 tomograms were uniformly read as normal. The study has merit in highlighting the 'abnormalities' of the pituitary fossa in what appear to be a group of normal controls, and to stress the phenomenon of observer variations. It is suggested, therefore, that sella tomograms alone are incapable of diagnosing with sufficient accuracy the presence of pituitary microadenoma in a young woman and, therefore, should not be performed as a routine in the evaluation of patients suspected of prolactin secreting microadenoma.

Adenoma↗

The role of high resolution computed tomography in evaluating disease of the middle ear.

Successful temporal bone imaging demands appropriate modifications of the computed tomography (CT) scanner. While CT has been shown to be useful for demonstrating the detailed anatomy of the temporal bone, its role in the evaluation of middle ear pathology has not been investigated. Selective cases are presented to highlight the advantages of CT. Computed tomography is excellent in demonstrating soft tissue masses in the middle ear in inflammatory disease. It is also useful in accurately localizing bony fragments in trauma, as well as determining the status of the ossicles. Disease solely involving the tympanic membrane can be diagnosed on CT without subjecting the patient to surgical exploration.

Adult↗

Computed tomographic anatomy of the temporal bone.

With the recent development of high-resolution computed tomography (CT), there is a growing need to explore the full potential of this new method in demonstrating the detailed anatomy of the temporal bone. For this purpose, dry skulls with intact ossicles were scanned in axial and coronal projections. The detailed CT anatomy of the temporal bone was documented, complemented by images from live patients. Because of its superior contrast resolution, CT was able to demonstrate numerous structures, such as the tympanic membrane, ossicles, and supporting structures, hitherto never or poorly visualized by any other method. In addition, the ease by which axial sections of the temporal bone could be obtained is of great benefit in displaying several structures previously difficult to evaluate.

Adult↗

Use of selective arteriography in the treatment of epistaxis.

Selective carotid arteriography can provide useful information in patients with massive epistaxis. It is limited in application because special techniques and preparation are necessary. Careful selection of patients is mandatory. It is not appropriate as a screening procedure for all patients with epistaxis. The procedure is especially useful when previous surgical control of the bleeding site has failed. Residual branches of the internal maxillary and ethmoid arteries are readily identified. The development of collateral blood flow to the nasal area from many sources can be recognized. The complexity of collateral blood flow emphasizes the necessity for controlling hemorrhage as close to the source as possible. At the same time, it suggests that long-term control of bleeding in the nasal area may fail due to this vast network of vessels.

Adolescent↗

Subarachnoid spread of ependymoma: diagnosis and evaluation of therapy by computerized tomography.

The potential of ependymomas to spread throughout the intracranial subarachnoid space is well documented, though the incidence is disputed. This relates in part to the time required for such metastases to produce symptoms. The diagnosis of such spread, however, is important for therapeutic management. This report demonstrates the effectiveness of computerized tomography in diagnosing spread of ependymoma throughout the basal cisterns and cerebral fissures.

Adult↗

Complete and partial trisomy of different segments of chromosome 8: case reports and review.

This report describes some of the clinical, chromosomal and radiological findings in three unrelated patients with trisomy 8 mosaicism syndrome (T8ms), two first cousins with trisomy 8q and a patient with trisomy 8p. On the basis of the phenotypic and cytogenetic findings seen in our six patients and those noted in previous reports, we concur with Riccardi & Crandall (1978) that most physical malformations seen in T8ms are associated with trisomy for the long arm of chromosome 8.

Abnormalities, Multiple↗

Cerebellar atrophy: the differential diagnosis by computerized tomography.

Seven patients with cerebellar atrophy were studied by computerized tomography. The radiographic findings were varied. They included enlargement of the lateral cisterns, loss of superior cerebellar vermian substance with prominence of the superior cerebellar cisterns, and fourth ventricle enlargements. The patterns of posterior fossa atrophy may suggest the etiology.

Adult↗

Multiplanar reconstruction as an aid in CT diagnosis.

Multiplanar reconstructions of the orbit, brain, and spine were performed on 60 patients with a variety of disorders. They were thought to provide significant useful information in 22 cases, some useful information in 26 cases, and no useful information in 12 cases. It is suggested that on-line reconstruction is a useful adjunct to neurologic CT.

Brain↗

The role of computed tomography in the evaluation of upper cervical spine pathology.

A series of nine patients with symptoms referable to the upper cervical spine were recently studied by both conventional radiographic techniques and computed axial tomography (CT), in an attempt to ascertain the effectiveness of CT in evaluating upper cervical spine pathology. We found CT a useful tool in diagnosing a variety of pathological conditions in this region, particularly when they involve subtle neural arch fractures, rotational deformities, or compromise of the neural canal.

Adult↗

Pluridirectional tomography in the evaluation of pituitary tumors.

A series of 110 patients with suspected pituitary tumors was recently evaluated by endocrinologic and neuroradiologic studies. Of the 77 patients in this series who underwent surgery, 74 had confirmed pituitary adenomas, two had suprasella tumors of the influndibulum, and one had an empty sella not previously diagnosed at pneumoencephalography. All 17 patients with normal plain skull films but abnormal thin section tomography who underwent surgery had documented pituitary tumors. This includes six patients who presented with amenorrhea and/or galactorrhea and normal baseline serum prolactin levels; the only abnormality was found on tomography of the sella. In the preoperative evaluation of these patients, pluridirectional tomography of the sella was the most sensitive indicator of intrasellar pathology.

Adenoma↗

Radiographic diagnostic evaluation and surgical treatment of multiple cerebellar, brain stem, and spinal cord hemangioblastomas.

Multiple hemangioblastomas of the central nervous system present a greater challenge in their diagnosis and treatment than do single hemangioblastomas of the cerebellar hemisphere. Improved radiographic techniques of tomographic vertebral angiography and computed axial tomography (CT) are of considerable value in the diagnosis of multiple cerebellar, brain stem, and spinal cord hemangioblastomas. Microsurgical techniques now allow for total operative removal of many of these lesions. A case report is presented to emphasize the radiographic diagnostic evaluation as well as the microsurgical technique for removal of multiple central nervous system hemangioblastomas.

Adolescent↗