S L Dodson | Search PubMed

PubMed1993

Effect of ketoprofen on Escherichia coli heat-stable enterotoxin-induced diarrhea of calves.

To evaluate the effect of ketoprofen on fecal output during secretory diarrhea, 16 calves were given approximately 200 micrograms of heat-stable Escherichia coli enterotoxin by suckling on 2 occasions. On one day, treatment was not administered. On the other day, either 3 mg of ketoprofen/kg of body weight (n = 8) or 6 mg of ketoprofen/kg (n = 8) was administered 1 hour before and 3 hours after administration of enterotoxin. Fecal output was no different after 8 or 24 hours from calves given 3 mg/kg, but fecal output was less at 8 hours and 24 hours for calves given 6 mg/kg (P = 0.0588), compared with the control day.

Animals↗

PubMed1992

Quantification technique for the middle latency response.

Few objective analysis techniques have been developed for, or applied to, the auditory evoked middle latency response (MLR). This report demonstrates the applicability of the Fsp statistical technique (Elberling and Don, 1984) to the MLR time domain. Subjects for this study were 10 normal hearing young adults. The stimuli were 60, 40, 20 dB nHL clicks and a NS control. Evoked responses were obtained as a series of 10,000 individual traces for each stimulus presentation and analyzed off line to determine the applicability of the Fsp technique. In addition, the effects of filtering and time window size were examined to determine the optimum collection characteristics for the Fsp analysis method. The results indicate that the Fsp technique is a viable tool for estimating signal-to-noise characteristics of the MLR. When using the Fsp technique with the MLR the high-pass filter should be set to 20 Hz so that a 50-msec time window can be used.

Acoustic Stimulation↗