Electrical injuries. Considerations for the perioperative nurse.
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Adult↗
Biomedical subjects
S L Bailey
Publications and source records attributed to S L Bailey.
Extent of blockade with various approaches to the lumbar plexus.
The extent of blockade when four different techniques were used for blocking the lumbar plexus was prospectively evaluated in 80 adult patients. The extent of blockade was measured by testing motor function of all nerves except the lateral and posterior femoral cutaneous nerves, which were evaluated by pinprick response. The posterior approaches of Dekrey at L3 (n = 20) and Chayen at L4-5 (n = 20) proved similarly effective in producing blockade of the femoral, obturator, and lateral femoral cutaneous nerves, as well as the nerves to the psoas muscle. The anterior approach of Winnie (femoral sheath or 3-in-1 block) using paresthesia (n = 20) or peripheral nerve stimulation (n = 20) proved effective in producing blockade of the femoral and lateral femoral cutaneous nerves, but ineffective for obturator nerve blockade. None of the four techniques produced blockade of the sacral plexus. Perhaps our means of assessing blockade (motor) is what produced the difference between our findings and those of others.
Humans↗
Gas chromatographic/mass spectrometric determination of aniline in food oils associated with the Spanish toxic oil syndrome.
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Aniline Compounds↗
Loss of coproporphyrin by centrifuging urine samples before liquid-chromatography.
We have previously reported a "high-performance" liquid-chromatographic procedure for urinary porphyrins. While attempting to automate this procedure, we discovered that coproporphyrin could be partly or completely lost from urine samples if they were centrifuged or filtered before analysis. The loss is related to the amount of precipitate in each sample, acidic urines showing the greatest losses. If samples are alkalinized before centrifugation, the loss is prevented.
Centrifugation↗
Using water mist to reduce self-injurious and stereotypic behavior.
A mist of water sprayed in the face was used as a punisher for stereotypic and self-injurious behaviors by a boy diagnosed as severely mentally retarded with autistic-like behaviors. The boy had a long history of mouthing and hand-biting behaviors. The latter behavior was evinced by noticeable scar tissue on the backs of his hands. The study took place in a self-contained public school classroom for autistic children and other children with severe communication disorders and functional mental retardation. An ABAB withdrawal design with no treatment probes demonstrated the rapid and dramatic suppressive effects that the response-contingent water mist had on the target behaviors. This procedure was taught to classroom personnel who were able to maintain the suppression with minimal interruption of educational programming for the subject or his peers. No adverse physical effects were observed nor did the child attempt to escape or struggle against the procedure. The results are discussed in relation to ethical considerations and the use of response-contingent aversive stimulation.
Autistic Disorder↗
Development and utilization of a procedure for measuring urinary porphyrins by high-performance liquid chromatography.
We describe a procedure for determining the five principal urinary porphyrins--uroporphyrin, heptacarboxylporphyrin, hexacarboxylporphyrin, pentacarboxylporphyrin, and coproporphyrin--by using high-performance liquid chromatography (HPLC). The method involves a 12- to 15-min isocratic separation on a Bondapak Phenyl column. Studies have indicated that urine samples must be preserved to maintain porphyrin stability for extended periods. We have found that the pH of preserved samples must be adjusted into the acidic range before the samples can be accurately analyzed by this HPLC procedure. Our studies demonstrate that good reproducibility and recovery are achieved with this method. Urinary porphyrin values for normal and porphyric individuals are reported.
Chromatography, High Pressure Liquid↗
Stimulus overselectivity in learning disabled children.
Stimulus overselectivity, a phenomenon exhibited by autistic and institutionalized retarded individuals, was examined in mildly handicapped and nonhandicapped public school children. Subjects were 16 young, educable mentally retarded, 16 learning disabled, 15 nonhandicapped first- and second-graders, and 16 older, educable retarded students. The children were trained on a 3-component visual discrimination task and then tested on individual elements to determine which element or elements were controlling subject responses. Nine of the young educable mentally retarded children and eight of the learning disabled students showed some overselectivity. The majority of overselective retarded children were controlled by only one of the three components of the training cue, whereas the majority of the overselective learning disabled children responded to the discrimination task on the basis of two of the three components. No overselectivity was exhibited by the nonhandicapped students. All three cue components were also functional in controlling the responding of 14 of the 16 older retarded students, but two children were under the control of only one cue. The research indicated that in terms of overselectivity, learning disabled children respond more like young, mildly retarded children than they do like nonhandicapped ones. The demonstration of stimulus overselectivity in a sizable portion of a learning disabled sample may have implications for a more empirically based approach to this handicapped population.
Attention↗
Drug treatment for hyperactivity: controversies, alternatives, and guidelines.
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Amphetamines↗
Morningness-eveningness and early-morning salivary cortisol levels.
The purposes of this exploratory study were: (1) to describe a 2-h segment of the early-morning salivary cortisol levels of morning (M) and evening (E) types of healthy, day-active adults on one morning; and (2) to compare selected demographic and sleep characteristics. The sample consisted of 20 subjects, aged 23-39 years, 10 of each type. Measures included: morningness-eveningness questionnaire score, demographic information, self-report sleep characteristics, and self-report of well-being. Beginning with time of arising, seven salivary samples were collected at approximately 20-min intervals. Among the sleep variables, bedtime (p = 0.005), time of mid-sleep (p = 0.002), and arising time (p = 0.043) were later in the E group as compared to the M group. Six M and one E subject awoke spontaneously on the morning of sampling without an awakening aid (p = 0.018). Even though total hours of sleep were comparable between groups, E subjects reported feeling less rested in the morning (p = 0.019). Although mean M group salivary cortisol levels were greater than mean E group levels for each sampling time, there were no significant group differences. Eight M subjects reached a sampling period salivary cortisol peak by 50 min after arising, contrasted with six E subjects who reached their peak at that time. These preliminary findings suggest that E types demonstrate lower morning arousal and a delay in their early-morning peak of salivary cortisol relative to M types. Further study is needed to explore the relationship between M and E types, their sleep-wake patterns, and cortisol secretion patterns.
Adult↗
Potential mediators, moderators, or independent effects in the relationship between parents' former and current cigarette use and their children's cigarette use.
Research consistently has shown that cigarette use by adolescents is related to their parents' use and to particular characteristics of the family environment, but few studies have examined the linkages between parents' smoking behavior and other family characteristics to explain adolescents' smoking. In this study, we tested mediator, moderator, and independent models for their ability to characterize the relationship between parents' and their children's smoking. A sample of 719 matched pairs of parent (usually mother) and child was used. Respondents were part of an ongoing randomized evaluation of the Drug Abuse Resistance Education (DARE) Project in Illinois, and the subset of data used in these analyses was collected in 1991, when the youths were in the sixth or seventh grades. Results of logistic regression provided the greatest support for the independent model, which suggests that the effects of parents' smoking and familial characteristics on adolescents' smoking are not linked. Results also supported those found by other researchers by showing that parents' former smoking is associated with adolescents' current smoking. Significant family characteristics were family disunion and parents' awareness of their child's activities. These results suggest, in part, that children at any age may have the capability of storing memories of their parents' smoking, memories that influence their own smoking; also, characteristics of the family environment, independent of parents' smoking behavior, have an effect on adolescents' smoking. Prevention implications and recommendations are also discussed.
Adolescent↗
Long-term evaluation of drug abuse resistance education.
Project DARE (Drug Abuse Resistance Education) is the most prevalent school-based drug-use prevention program in the United States, but there is little evidence of its effectiveness. Results from a longitudinal evaluation of the program in 36 schools in Illinois provide only limited support for DARE's impact on student's drug use immediately following the intervention, and no support for either continued or emerging impact on drug use 1 or 2 years after receiving DARE instruction. In addition, DARE had only limited positive effects on psychological variables (i.e., self-esteem) and no effect on social variables (e.g., peer resistance skills). Possible substantive and methodological explanations for the relative lack of DARE's effectiveness observed in this study are discussed.
Adolescent↗
Quantification of selected herbicides and chlorinated phenols in urine by using gas chromatography/mass spectrometry/mass spectrometry.
We have developed a method for determining selected chlorinated phenols and phenoxy herbicides in urine. The process of preparing the samples includes acid hydrolysis, extraction with benzene, derivatization with diazoethane, and column chromatography cleanup. We quantify the more volatile compounds by using capillary column gas chromatography/positive chemical ionization/mass spectrometry/mass spectrometry. Less volatile compounds are quantified by using electron capture negative chemical ionization in a single stage mass spectrometry mode. Quality control samples are included in each analytical run, and the results demonstrate that the analytical system is in control. Positive values for the target analytes are determined on the basis of appropriate relative retention time, a signal-to-noise ratio greater than 3:1, and a calculated concentration greater than 1 ppb. We determine the chlorine isotope ratios for each compound to assess the presence or absence of interferences. This analytical method has been applied in a case-control study of 199 individuals to examine exposure to the 12 target analytes.
Child↗
Psychosocial factors associated with cardiovascular reactivity in older adults.
This study examined associations of psychosocial factors with cardiovascular reactivity in two groups of men and women--spouse caregivers of individuals with Alzheimer's disease (M age = 69.4 N = 82) and controls (M age = 68.5, N = 78) group-matched for age and gender. Cardiovascular responses to an emotional task (speech sample about one's spouse) yielded higher systolic and diastolic blood pressures (SBP, DBP) than a spoken cognitive task, which in turn yielded higher BPs and heart rate (HR) than the baseline rest period. HR was greater in response to the two tasks than in response to the baseline period, but it did not differ across tasks. Regression models of SBP, DBP, and HR reactivity in response to the two tasks demonstrated that after controlling for hypertension and gender, combinations of hostility, anger expression, avoidance coping, Type A behavior and Expressed Emotion (criticism) explained more reactivity in response to the emotional (8-12%) than the cognitive task (4-7%). Caregivers were more reactive than controls only if they were hypertensive. Psychosocial factors may be as important in explaining reactivity in older adults as in younger adults.
Adaptation, Psychological↗
Sciatic nerve block. A comparison of single versus double injection technique.
BACKGROUND AND OBJECTIVES: Two techniques, single versus double injection, for blocking the sciatic nerve via the classical (Labat) approach were prospectively evaluated for onset and efficacy of block in 50 adult patients undergoing lower extremity surgery. The tibial, common peroneal, and posterior femoral cutaneous nerves were evaluated at 5, 10, 15, 20, 30, and 45 minutes after the initial injection of local anesthetic. Motor function was used to assess the block of the tibial and common peroneal nerves while pinprick response was used to assess block of the posterior femoral cutaneous nerve. METHODS: Group 1 (n = 25) received a single injection of 20 mL of an amide-ester solution (1% lidocaine/0.2% tetracaine) with epinephrine 1:200,000 when either component of the sciatic nerve (tibial or peroneal) was identified with the aid of a peripheral nerve stimulator. Group 2 (n = 25) received two 10 mL injections of the same solution with the tibial and peroneal components of the sciatic nerve being identified and injected separately (through the same skin wheal in serial fashion by withdrawing and redirecting the needle). The two groups were compared at each of the time intervals with analysis of variance. RESULTS: Group 2 (double injection) showed faster onset and better efficacy (P < .05) at all time intervals evaluated. CONCLUSIONS: The double injection technique for sciatic nerve block via the classical approach results in a more rapid onset and increased efficacy of block than that of the single injection technique.
Adolescent↗