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Biomedical subjects

S Kuwabara

Publications and source records attributed to S Kuwabara.

225 records · Page 13Linked to original sources

Prenatal diagnosis of open spina bifida by MRI and ultrasonography.

A case that was diagnosed prenatally as having open spina bifida by magnetic resonance imaging (MRI) and ultrasound (US) examination is reported. At the time of the third US examination, the spina bifida cystica was detected, but it could not be determined by US whether it was open or closed spina bifida. A lumbosacral skin defect was detected on MRI, which permitted prenatal diagnosis of open spina bifida. Surgical repair was performed immediately after delivery. Prenatal intrauterine evaluation of the fetal CNS morphology and malformation has advanced with the improvement of diagnostic tools. Each diagnostic tool, however, has its own advantages and disadvantages. In prenatal intrauterine evaluation, it is important that observation be made through the combined use of multiple diagnostic tools.

Adult↗

Histogenesis and clinicopathological characteristics of superficially spreading carcinoma of the esophagus.

To explore the possible histogenesis of superficially spreading carcinoma of the esophagus, the clinicopathological features of these tumors (n = 44) were compared with those of ordinary superficial carcinoma (n = 163). Tumors of a heterogeneous histological type and having in situ carcinoma components were significantly more common (P < .05), and the number of residual squamous islands was significantly greater (P < 0.05) in the former group than the latter. Furthermore, the tumor size was not different among in situ, intramucosal, and submucosal carcinomas of the former, whereas the tumors became larger according to the depth of invasion in the latter group. These results indicate that the collision of multiple simultaneously developing superficial tumors is a plausible histogenesis of superficially spreading carcinoma of the esophagus.

Aged↗