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Biomedical subjects

S Kubo

Publications and source records attributed to S Kubo.

At least 595 records · Page 33Linked to original sources
PubMed1976

[Study of the clinical effects of sulpiride and perphenazine in 82 schizophrenic patients by the double blind method].

Our clinical and statistical evaluation of Sulpiride and Perphenazine was carried out over a 10 week period, in 82 patients of both sexes, aged 20 to 56 years. All were chronic patients with a symptomatic profile of apathy, lack of initiative but with the personality relatively well preserved in 56 patients. The daily dosage varied from 300 to 1,200 mg Sulpiride orally and 12 to 48 mg Perphenazine. The effects of therapy have been received globally and individually at the beginning, 4th, 8th, and the end of the 10th week using the B.P.R.S. modified by the clinic of Neurology and Psychiatry of the University of Hiroshima. Using "Armitage's Restricted Sequential Design", there was no significant difference between the therapeutic effects of these 2 neuroleptics. However, Sulpiride appeared more beneficial following the review during the 8th week and the 4th week.

Adult↗
PubMed1975

Comparative studies on 5,5'-dithiobis-(2-nitrobenzioc acid)-treated myosins.

Myosins prepared from chicken and rabbit fast and slow muscles were treated with 5,5'-dithiobis-(2-nitrobenzoic acid) (Nbs2). About half of the thiol groups of the fast muslce myosins reacted with Nbs 2, but in slow muscle myosins, only about 10-20% of the thiol groups reacted. This treatment removed 50-60% of the L2 components, Nbs2 light chain, from fast muscle myosins, but did not result in specific dissociation of the light chains in slow myscle myosins. The treatment sometimes released L4 component from chicken muscle myosins instead of L2 component. The changes of myosin ATPase [EC 3.6.1.3] activities caused by this treatment did not correlate with the release of Nbs2 light chain, but were dependent upon the species, chicken or rabbit.

Adenosine Triphosphatases↗