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S Krishnaswami

Publications and source records attributed to S Krishnaswami.

141 records · Page 8Linked to original sources
PubMedDate not supplied

Distribution of Body Mass Index in Indian patients with coronary artery disease.

To study the distribution of overweight and obesity among Indian patients with coronary artery disease (CAD), a cross-sectional analysis of computerized data on patients, proved to have CAD by selected coronary arteriography, was carried out. There were 1078 patients, with 1052 males (mean age +/- SD:50 +/- 7.5) and 26 females (mean age +/- SD:47.7 +/- 8). Of these, 22 percent had single vessel disease, 38 percent two vessel and 40 percent three vessel disease. The Body Mass Index (BMI) was calculated from the height and weight data. BMI over 27 kg/m2 was defined as overweight and that over 30 kg/m2 as obese. Data analysis revealed that only 8.2 percent of patients with CAD were overweight, of whom 2.2 percent were obese. CAD was seen in Indians with BMI from 15 kg/m2 onwards. The BMI in the risk factor groups of smoking, diabetes and hypertension was not different when compared to those without the risk factors. However, the BMI was higher in those with a positive family history (p < 0.01). BMI was higher in the businessmen and executives but did not qualify for overweight or obesity group. BMI did not correlate with the various lipid fractions studied. It is concluded, that in Indian patients, angiographically proved coronary artery disease can be seen with low BMI.

Adult↗
PubMedDate not supplied

Plasma insulin levels in coronary artery disease.

Seventy two consecutive patients without a history of diabetes and normal fasting plasma glucose were included in this study of insulin levels. Standard oral glucose tolerance test with 75 gm glucose and fasting and two hour insulin levels were estimated in all patients. Coronary artery disease (CAD) was confirmed or excluded by selective coronary arteriography. In 20 patients, CAD was diagnosed by electrocardiographic (ECG) and clinical evidence of earlier myocardial infarction. Mean fasting plasma insulin was 31.40 +/- 22.2 IU/dl in the CAD positive and 32.3 +/- 13.6 IU/dl in the CAD negative group. The mean two hour plasma insulin was 274.6 +/- 301.1 IU/dl in the CAD positive and 104.8 +/- 74.9 IU/dl in the CAD negative group (p < 0.04). Two hour plasma insulin levels were significantly higher in patients with atherosclerotic coronary artery disease. It is concluded that the estimation of a two hour plasma insulin level after 75 gm of glucose load, could help differentiate CAD from normals.

Coronary Disease↗
PubMedDate not supplied

Exercise capacity in untrained normal adults: a nomogram for Indians.

The exercise capacity of 155 hospital-based patients (125 males and 30 females) who underwent treadmill testing and coronary angiography for investigation of chest pain was used to derive regression equations for exercise capacity (METS) against age. A regression equation [18 - 0.16 x (age)] for males and [11 - 0.84 x (age)] for females was obtained. Using these equations an exercise capacity nomogram was developed. From this nomogram the predicted exercise capacity was calculated for another set of 228 patients (209 males and 19 females) whose treadmill tests were negative. The results confirmed that the nomogram could be applied to determine the expected and actual exercise capacity of Indians within a mean difference of 0.08 METS. This nomogram is being offered for clinical, therapeutic and preventive use for Indian patients.

Adult↗