Search PubMed⌕ Search

Biomedical subjects

S Koide

Publications and source records attributed to S Koide.

At least 145 records · Page 8Linked to original sources
PubMed1984

Endotracheal tube with movable blocker to prevent aspiration of intratracheal bleeding.

A newly developed endotracheal tube with a movable blocker was found to be lifesaving in patients with copious and persistent intratracheal bleeding. The cases of 4 patients are presented. In 3 patients, severe intratracheal bleeding was attributed to the extensive bronchopulmonary laceration caused by blunt chest trauma. In the remaining patient, the bleeding was due to rupture of the sutured site in the right pulmonary artery; the rupture was caused by a postoperative bronchopleural fistula. In these patients, spread of blood was completely prevented and pulmonary resection was performed safely by using the blocker in this new device.

Adult↗
PubMed1983

Specific antimononuclear phagocyte monoclonal antibodies. Application to the purification of dendritic cells and the tissue localization of macrophages.

3C10 and 1D9 are two related monoclonal antibodies that specifically identify human mononuclear phagocytes in a large number of sites, including blood monocytes, alveolar macrophages, and macrophages in tissue sections of spleen, lymph node, and skin. The antigen persists on monocytes cultured for greater than 4 wk, but it is not found on giant cells. The 3C10-1D9 determinant is carried by a 55 kD polypeptide, is expressed at approximately 40,000 copies per monocyte, and is protease sensitive. The antigen is clearly different from HLA-class II or Ia-like antigens that have been studied with a new monoclonal 9.3F10. The 9.3F10 antigen is found on B cells, dendritic cells and monocytes; is protease resistant, and occurs on a 33-29 kD doublet typical of class II products. The 3C10 monoclonal provides a clear distinction between human mononuclear phagocytes and dendritic cells. First, monocytes and lymphocytes can be eliminated from plastic-adherent mononuclear cells using 3C10, complement, and two previously described cytotoxic antibodies, BA-1 (anti-B cell) and Leu-1 (anti-T cell). As a result, the trace dendritic cell component of blood can be enriched to considerable purity (65-75%) and yield. Second, immunocytochemical staining of tissue sections reveals that 3C10+ macrophages are anatomically segregated from dendritic cells. Large numbers of 3C10+ cells are found in red pulp of spleen and in regions surrounding lymphatic channels of lymph node. However, 3C10+ macrophages are scarce in white pulp of spleen and the lymphocyte-rich cortex of node that are the sites where dendritic cells are localized. 3C10+ cells in skin are found in the dermis, particularly in leprosy infiltrates, but the Langerhans' cells of epidermis are 3C10-. The distinctive localization of macrophages and dendritic cells is consistent with their respective functions as effector and accessory cells in the immune response.

Animals↗
PubMed1983

Evaluation of intracardiac thrombus with computed tomography.

Left atrial (LA) and left ventricular (LV) thrombus was evaluated by computed tomography in 56 patients. The patients were divided into 2 groups: Group I, 28 patients with mitral valve disease, and Group II, 28 patients with myocardial infarction. Computed tomography and 2-dimensional echocardiography were performed in all the patients studied. Cineangiocardiography was performed in all Group I and in 13 Group II patients. Open heart surgery or autopsy was performed in all Group I and 4 Group II patients. The sensitivity in detecting LA thrombus was 100% with computed tomography, 70% with angiocardiography, and 60% with 2-dimensional echocardiography. The specificity in detecting LA thrombus was 91% with computed tomography, 86% with 2-dimensional echocardiography, and 88% with angiocardiography. Thrombi located at the LA appendage were associated with great difficulties in detection by other methods, but were well delineated with computed tomography. LV thrombus was also visualized by computed tomography with similar or greater accuracy than other diagnostic methods, although the sensitivity and specificity were not ascertained because surgery or autopsy was performed in only a minority of Group II patients. Therefore, as far as the detection of intracardiac thrombus is concerned, computed tomography has the advantage of offering uniform slices of the heart in an attempt to detect thrombi in unknown areas of cardiac chambers, including the LA appendage or LV apex, without being disturbed by the surrounding cardiac and noncardiac structures. Thus, computed tomography has excellent accuracy in the detection of intracardiac thrombus.

Adult↗
PubMed1983

Plain radiographic diagnosis of thrombosis of left atrial appendage in mitral valve disease.

Conventional posteroanterior chest radiographs of 42 patients with mitral valve disease who had had surgery were analyzed, and particular attention was directed to the presence or absence of the convexity of the left lower midcardiac border (left atrial segment). The flatness or concavity of this segment, despite other evidence of left atrial enlargement, was observed in six (60%) of 10 patients who had left atrial thrombosis, and in three (9%) of 32 patients who did not have thrombosis (false positive diagnosis). Four of the 10 patients who had left atrial thrombosis did not show this finding on the radiographs (false negative diagnosis). One of these four had a thrombus only against the posterior wall of the body of the left atrium. Therefore, the accuracy in the diagnosis of thrombosis of the left atrial appendage was 66.7% (six of nine) for patients who had thrombosis of the appendage. Standard chest radiographs are important in the evaluation of the patient with thrombosis of the left atrial appendage.

Adult↗
PubMed1983

Experience using the angioplastic procedure of the pulmonary artery in patients with lung cancer.

Eight cases of bronchogenic carcinomas which underwent angioplastic procedures were reported. We believe that the angioplastic procedure, as in the case of the bronchoplastic procedure, is a useful operative method to preserve normal lung tissue particularly in patients of advanced age and/or limited respiratory reserves. With this procedure we can avoid pneumonectomy and assure patients a good postoperative life. With respect to angioplastic procedures caution must be exercised concerning the following items. 1) Infection may cause ruptures or stenosis at the site of the suture line. 2) It is necessary not to cause stenosis in the suture line of the pulmonary artery since the pulmonary artery is in a low pressure system and the wall is thin.

Adult↗
PubMed1983

Experimental study on angioplastic procedures of the pulmonary artery.

To solve problems arising during angioplastic procedures of the pulmonary artery, experimental studies using canine lungs were performed. Since the lung has dual adjacent components, i.e. pulmonary arteries and bronchi, sleeve resection of the pulmonary artery should be limited in length when not combined with bronchoplastic procedures. In such cases we used Gore-Tex as an artificial graft for replacement of the resected pulmonary artery and obtained good results. During the angioplastic procedures the main pulmonary artery and/or bronchus may be completely occluded, hence the risk of acute pulmonary edema in the remaining lung increases with long operations. From the results of this experiment it appears that the time required for operation with interruption for both perfusion and ventilation is about 2 hours.

Animals↗
PubMed1983

Leiomyoma of the lung--report of a case.

A case of leiomyoma of the lung appearing in a 28-year-old female with a history of supracervical hysterectomy for uterine leiomyoma 10 years previously is reported. She had no symptoms but chest X-ray film showed a single nodule in the right upper lobe which slowly increased in size over a 3 year interval. At thoracotomy the tumor measured 4 cm in size and was sharply demarcated from the lung parenchyma without any connection with the bronchial tree. Histological findings proved this tumor to be a leiomyoma with no atypical cells or mitoses showing a close resemblance to uterine leiomyoma. Metastasizing uterine leiomyoma is very rare. Because these leiomyomas behave clinically as a low grade malignancy despite a histologically benign appearance, careful long term follow-up is necessary.

Adult↗