[Anomalous origin of the left coronary artery from the pulmonary artery in an adult--angiographic and hemodynamic follow-up after surgical repair].
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Biomedical subjects
Publications and source records attributed to S Koh.
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In order to check the safety of diagnostic continuous wave ultrasonic irradiation, a clinical study, serum hemoglobin level and scanning electron microscopic finding of ultrasound irradiated blood were studied. The following results were obtained. 1. Clinical study: Ultrasonic examination were carried out on 6788 pregnant women at the first trimester of gestation. In test group, rate of abortion and premature delivery, fetal malformation and small for date gestation were not significant higher than those of control group. Neither timing of first examination nor number of examinations at the first trimester seemed to increase above mentioned abnormality. 2. Serum hemoglobin level: Blood exposed 2 to 12 hours to low intensity ultrasound (20 mw/cm2) showed significantly higher serum hemoglobin level than that of control group. However, blood exposed 40 to 120 minutes to high intensity ultrasound (2.6 w/cm2) have significant higher hemoglobin level than that of control group. 3. Scanning electron microscopic finding: Erythrocyte exposed 4 to 24 hours to low intensity ultrasound have no significantly different scanning electron microscopic finding when compared to that of control group. However, deformed erythrocytes were significantly higher than those of control group after exposure to 40 to 120 minutes to high intensity ultrasound.
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In one of the first longitudinal studies of 163 non-Caucasian women, comprehensive coagulation, fibrinolysis and platelet function tests were performed before and during 24 months of oral contraceptive pill usage containing 50 microgram estrogen. Results of this ongoing study indicate a state of abnormal coagulability with increase in fibrinogen, prothrombin, Factor V and Factor X. There was also a decrease in antithrombin III level. There was a shortening of overall clotting parameters measured by prothrombin time and Kaolin cephalin time. The significance of these changes in the aetiology of thromboembolism is discussed.
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Tests of coagulation, fibrinolysis, and platelet function were performed in 17 patients with intact molar pregnancies. Women with intact molar pregnancies had higher fibrinogen factor VIII, and fibrinogen degradation products, concentrations and lower prothrombin, factor X, plasminogen, and plasminogen activator concentrations than controls with normal pregnancies. They also had reduced platelet counts and thromboelastographic values, which indicated hypocoagulability. These results suggest that intravascular coagulation occurs in intact hydatidiform molar pregnancies.
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