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Biomedical subjects

S Kiyono

Publications and source records attributed to S Kiyono.

At least 55 records · Page 3Linked to original sources
PubMed1980

Sleep-waking cycle in microencephalic rats induced by prenatal methylazoxymethanol application.

Sleep-wakefulness cycle of adult microencephalic rats due to prenatal administration of methylazoxymethanol (MAM) acetate at the dose of 20 mg/kg on the 15th day of gestation showed no difference from the normal control group, whereas at the dose of 25 mg/kg, %PS and PS/TS decreased significantly. MAM-induced microencephalic rats revealed a significant increase of spindle bursts during PS, suggesting that their PS is less deep than that of the controls.

Animals↗
PubMed1980

Nocturnal sleep in severely mentally retarded children: abnormal EEG patterns in sleep cycle.

Sleep EEG patterns in 43 mentally retarded children (from 4 months to 80 years of age) were studied throughout nocturnal sleep and the following results were obtained. (1) Twenty-two cases evidenced normal sleep patterns that could be classified into 6 stages. (2) The 21 other cases showed some abnormal sleep EEG patterns as follows: (a) absence of sleep spindles (n = 18) which included cases of high voltage fast activity (n = 2) and cases of low voltage activity throughout nocturnal sleep (n = 3); (b) indistinguishable delta and theta activities (n = 1), extreme spindle-like pattern (n = 1), absence of REM sleep (n = 1). (3) The severely mentally retarded children under 18 months had definitely decreased spindle activity in comparison to the values obtained by other authors from normal children. (4) The majority of the abnormal sleep EEG patterns occurred during light sleep. (5) A significant decrease in DQ was found in children with abnormal sleep patterns throughout NREM sleep as compared with those in whom abnormal EEGs occurred only during stages 1 and 2. (6) It was concluded that the EEG recorded in nocturnal sleep may serve as a useful indicator of abnormality in mentally retarded children.

Cerebral Cortex↗