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Biomedical subjects

S Kitamura

Publications and source records attributed to S Kitamura.

At least 1,045 records · Page 58Linked to original sources

A case of the left innominate vein passing behind the ascending aorta.

The authors observed the postaortic left innominate vein, which passed behind the ascending aorta, in the body of a 69-year-old Japanese male during dissection in 1979. In this case, no rudiment of the ordinary left innominate vein could be found in front of the arteries arising from the arch of the aorta. There are few reports of this anomaly and an extensive search of the available literature revealed only ten cases, including three in Japan. Adachi classified the postaortic left innominate vein into two types, types I and II, on the basis of the positional relation between the left innominate vein and the ligamentum arteriosum. Our case was of type I, in which the left innominate vein passed ventral to the ligamentum arteriosum and ran across from left to right behind the ascending aorta to join the right innominate vein. The embryological explanation which generally is accepted for the postaortic left innominate vein lies in the transposition of a transverse connection, which becomes the left innominate vein in a later stage of development, between the left and right anterior cardinal veins from the ventral to dorsal sides of the rudiment of the ascending aorta.

Aged↗

Results of aortic valve replacement in patients with a narrow aortic annulus: effects of enlargement of the aortic annulus.

Among 71 patients who underwent aortic valve replacement with a Björk-Shiley prosthesis, 13 (18.3%) had concomitant enlargement of the aortic annulus at the noncoronary cusp. Mean age of the 13 patients at operation was 34.4 years. Nine of them had combined mitral stenosis. One patient died in the early postoperative period, for an operative mortality of 7.7%. The aortic annulus before enlargement was 20.9 mm and after enlargement, 24.3 mm on the average. The net increase in diameter of the aortic annulus was 3.3 mm, which was statistically significant (p < 0.005). The tissue diameter of the prosthesis was 1.2 mm larger on the average than the aortic annulus diameter before enlargement, and a prosthesis at least one size larger could be implanted in the narrow aortic annulus.

Adolescent↗

Further studies of sulfoxide-reducing enzyme system.

Various kinds of flavoenzymes such as NADPH-cytochrome c reductase, NADH-cytochrome b5 reductase, xanthine oxidase, lipoamide dehydrogenase and NADH dehydrogenase supplemented with their electron donors exhibited the sulfoxide reductase activity in the presence of a partially purified soluble factor from guinea pig liver. The present study suggests that new electron transfer systems in which the soluble factor functions as an electron carrier coupled with flavoenzymes described above are responsible for the sulfoxide reduction.

Animals↗

Effect of heparin Na on the action of various bronchoconstrictors in guinea pig tracheal strips.

The effect of heparin Na on the actions of various bronchoconstrictors was examined. Guinea pig tracheal strips were suspended in bioassay glass chambers and superfused with Krebs-Henseleit solution, pH 7.4, at 37 degrees C saturated with oxygen and carbon dioxide gas (95:5, v/v). Contraction of the tissue was detected by an isotonic transducer and displayed on a polyrecorder. Heparin Na attenuated histamine-, prostaglandin F2 alpha-, acetylcholine-, serotonin-induced contractile responses dose-dependently, and shifted the dose-response curves of histamine, prostaglandin F2 alpha, acetylcholine, serotonin and bradykinin downward.

Acetylcholine↗