Search PubMed⌕ Search

Biomedical subjects

S Kessler

Publications and source records attributed to S Kessler.

At least 181 records · Page 10Linked to original sources
PubMed1972

Genetic variation in activity of enzymes involved in synthesis of catecholamines.

A genetic analysis of differences in adrenal phenylethanolamine N-methyltransferase (EC 2.1.1.X) and tyrosine hydroxylase (EC 1.99.1.X.) and brain tyrosine hydroxylase was performed in three inbred mouse strains. In adrenal glands, the pattern of inheritance of both enzymes was similar; genes carried by the CBA/J strain appeared to be dominant to those of the other strains. The pattern of inheritance of tyrosine hydroxylase activity in adrenals differed from that in the brain. In both tissues, dominant genes appeared to determine intermediate, rather than extreme, levels of enzyme activities.

Adrenal Glands↗
PubMed1970

Genetic variation of cholesterol ester content in mouse adrenals.

Total cholesterol concentrations in muscle, liver, and plasma do not differ significantly between adult male C57BL/10J and DBA/2J mice. In the adrenal glands of these two strains, of their hybrids, and of AC mice, concentrations of free cholesterol vary by 5 percent. Adrenals from C57 mice, however, contain six times as much esterified cholesterol as adrenals from AC or DBA mice. The intermediate concentrations of cholesterol esters in F(1) hybrids suggest that the difference in this measure is inherited additively. The finding of variation in adrenal cholesterol within a species is useful for the further study of the role of cholesterol in steroidogenesis by means of genetic analysis.

Adrenal Glands↗