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Biomedical subjects

S Kenan

Publications and source records attributed to S Kenan.

At least 73 records · Page 4Linked to original sources

Limb salvage in pediatric surgery. The use of the expandable prosthesis.

Limb sparing in growing children has proved to be very effective from an oncologic perspective, with good, long-term acceptance by the patients. As in the adult, when performed by experienced surgeons, limb sparing neither compromises the survival rate nor significantly increases the local recurrence rate, compared with cross-bone amputation. Discussions include patient evaluation, surgical options, materials and methods, and results.

Bone Neoplasms↗

Case report 623. Osteitis condensans of the left clavicle (OCC).

A case of OCC in a 35-year-old woman is presented. Proof was obtained by open biopsy. This rare entity is benign and its etiology is still obscure. No definite association with osteitis pubis or osteitis condensans ilii has been reported. The involvement of the clavicle is invariably unilateral. The clinical and radiographic characteristics of this benign condition have been discussed and the differential diagnosis has been considered. Consideration should be given to the concept that if the imaging features are characteristic, as in this case, biopsy may not be necessary.

Adult↗

CO2 laser cauterization of giant-cell tumor margins.

The CO2 laser was evaluated to determine its effectiveness for marginal cauterization of giant-cell tumors after resectional curettage. Average power densities of 11-53 W/cm2 for corresponding application times of 120 and 60 seconds were found to produce 30 degrees temperature rises in fresh human femoral heads. This temperature was adequate to achieve thermal necrosis of the tumor margins to a depth of 5 mm. CO2 laser resection was found to be accurate and reproducible. No damage to underlying hyaline cartilage and soft tissues was evident histologically at one and four weeks after experimental local laser cauterization of distal femoral condyles in rabbits.

Animals↗

Periosteal chondroma. A report of ten cases and review of the literature.

Periosteal chondroma is a slow-growing benign cartilaginous tumor of limited size arising within or under the periosteum, which, through constant pressure, induces cortical erosion and periosteal reaction. Ten new cases of periosteal chondroma are reported. All were treated by marginal or intralesional excision. No local recurrence was seen following this treatment. These patients demonstrated the clinical, roentgenographic, and pathologic features of this benign entity, which aid diagnosis, thereby avoiding overtreatment.

Adult↗

Juxtacortical liposarcoma. A case report and review of the literature.

Juxtacortical liposarcoma is an uncommon entity. The purpose of this paper is to report the case of a 63-year-old man with juxtacortical liposarcoma. Liposarcomas arising as surface lesions of bone are extremely rare. Histologically, juxtacortical liposarcoma is composed of myxoid and round-cell areas. Because of the extent of compartmental involvement and the high-grade malignancy, limb-sparing surgery was not considered for the patient. A review of the English literature on diagnosis and treatment indicates a grave prognosis.

Femoral Neoplasms↗

Osteosarcoma. Clinical and pathological considerations.

The current local recurrence rate following limb sparing surgery for osteosarcoma is on the order of 5 per cent. Major advances in both reconstructive surgery and adjuvant chemotherapy have dramatically improved the disease-free survival rate and the quality of life in patients with osteosarcoma.

Bone Neoplasms↗

The potential role of the laser in marginal sterilization of giant cell tumor following curettage.

Giant cell tumor is considered to be a lesion which behaves locally in an aggressive fashion and has a high local recurrence rate. Several physical adjuvant methods have been employed to reduce the local recurrence rate including cryosurgery with liquid nitrogen, phenol instillation, and the use of methylmethacrylate. In laboratory conditions, the authors applied a CO2 laser beam to eliminate traces of residual tumor tissue. As a mode of physical adjuvant treatment, use of the laser seems to be a promising technique for local tumor control.

Bone Neoplasms↗

Malignant transformation of fibrous dysplasia. A case report and review of the literature.

A 34-year-old man developed a spindle-cell sarcoma originating in a preexisting lesion of monostotic fibrous dysplasia. A review of the literature reveals 83 cases of a malignant degeneration in fibrous dysplasia; osteosarcoma was the most common type of tumor. The next most common were fibrosarcoma and chondrosarcoma. The malignant tumor usually developed in the third or fourth decade of life. The most frequent anatomic sites were the craniofacial bones, the femur, and the tibia. Twenty-three of the 83 cases were treated with local radiation. In fibrous dysplasia, any abrupt alteration in the clinical course, manifested by pain and swelling, raises the possibility of malignant degeneration.

Adult↗

Subperiosteal hemangioma. A case report and review of the literature.

Subperiosteal hemangioma (SPH), an exceptionally rare lesion, was diagnosed in a 68-year-old man. SPH is usually small and is most commonly located in the midshaft of a long tubular bone such as the tibia or fibula. A wide range of age groups is affected. SPH may present with mild pain or local swelling unassociated with trauma. Radiologically, it usually appears as a shallow cup-shaped depression surrounded by cortical thickening. Several other periosteal and intracortical lesions must be considered in the differential diagnosis, but the final diagnosis rests on microscopic evaluation. The treatment of SPH is marginal excision; local recurrences have not been reported after such treatment.

Aged↗

Cord compression as the presenting symptom of extradural malignant lymphoma.

Six patients with spinal cord compression as the presenting symptom of malignant lymphoma are described. These patients suffered from back pain for several months and were diagnosed after sudden paraparesis appeared. Five patients were treated by operative decompression followed by local irradiation, and all regained their motor function. A sixth patient presented with a more insidious paraparesis. A bone marrow aspiration established the diagnosis of malignant lymphoma, and this patient recovered with radiation and steroids alone. Thus, we recommend considering malignant lymphoma as a possible cause of acute cord compression, attempting to establish the diagnosis on an emergency basis within several hours, and attempting to achieve decompression with local radiotherapy and intravenous dexamethasone.

Adult↗

Another look at the pertrochanteric fracture of the femur: the relationship to osteoporosis.

Eighty-seven pertrochanteric fractures consecutively treated between the years 1978 and 1981 are reviewed. External and internal rotation types are described relative to their aetiology. The final typing of the fracture can be made only on reduction. What we have called 'internal rotation fractures' show an excellent correlation with the unstable fracture gradings described by Boyd, as well as very osteoporotic Singh gradings (1-3). It is contended that the latter is the main factor in its production as opposed to the more common external rotation variety. An appeal is made for recognition of the fracture, its reduction by means of external rotation and adequate fixation. Early weight bearing is not advised, in order to prevent subsequent varus deformity with extrusion of the implant.

Aged↗

Periosteal ganglion case report and review of the literature.

The first reported case of a periosteal ganglion to be documented by computerized tomography is presented. The lesion was located on the shaft of the tibia and was unrelated to ligamentous and joint structures. A review of the literature reveals that the most common site for this lesion is the upper leg, as noted in our case; for that reason, periosteal ganglion should be included in the differential diagnosis of any soft tissue lesion in this location. CT may be more useful than plain films to demonstrate periosteal ganglion when cortical erosion is absent.

Cysts↗

Clear cell sarcoma of the tendinous portion of the quadriceps muscle at the knee joint managed by limb-sparing surgery.

A case report of clear cell sarcoma of the tendinous portion of the quadriceps in the knee joint of a 33-year-old female is presented. This insidious, usually painless malignant tumor is often misdiagnosed and may be referred to the sports medicine specialist as a sport-related injury. The duration of symptoms and the size of the lesion are important prognostic factors. Wide excision or radical surgery is necessary to cure such tumors. With improved reconstructive techniques, including free vascularized myocutaneous flaps, limb-sparing surgery is now possible.

Adult↗