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Biomedical subjects

S Kawada

Publications and source records attributed to S Kawada.

At least 199 records · Page 11Linked to original sources

First rib resection in the treatment of the thoracic outlet syndrome.

The thoracic outlet syndrome is now generally accepted as an entity that involves all neurovascular compression symptoms of the upper extremities at the tight thoracic outlet. We have treated 19 patients who developed significant symptoms of neurological, arterial or venous compression. Twelve patients presented predominantly and their angiograms demonstrated tight thoracic outlets as the underlying cause of vascular compression. Twenty three first rib resections were performed through the transaxillary approach with apparently complete relief of the syndrome. The similar etiology of the thoracic outlet syndrome and subclavian vein thrombosis was discussed on the basis of angiographic findings. We emphasize to thoracic and cardiovascular surgeons that first rib removal through the transaxillary route is an easy and safe method as a modified thoracoplasty.

Adolescent↗

Resection of lung cancer involving the heart and great vessels.

Over the last six years at the Tokai University Hospital, 104 patients were operated on for the primary lung cancer. Twenty nine of these patients were submitted to extended operations, because cancer had invaded the heart and/or great vessels. In three cases, the left pneumonectomy with partial resection and suture repair of the descending thoracic aorta was performed. In 26 cases, intrapericardial ligation of the pulmonary vessels was carried out: nine of these patients underwent intrapericardial pneumonectomy with partial resection of the atrial wall and one patient underwent sleeve resection of the superior vena cava with graft (Gorétex) replacement. No extracorporeal apparatus was used in any cases of extended operations. The postoperative course was mostly uneventful and there were no cases of operative death. We believe that excision of lung cancer extending into the heart and great vessels can offer the patient every chance for a longer life, especially in the case of squamous cell carcinoma.

Adult↗

Evaluation of left atrial thrombus with computed tomography.

Left atrial thrombi were evaluated with computed tomography in 23 patients with mitral valvular diseases. In three of the patients, left atrial thrombi were delineated with computed tomography and were confirmed by cardiac surgery or autopsy. The minimum size of the thrombi detected tomographically was 3.5 gm. There were no false-positive or false-negative results with computed tomography in 13 patients who subsequently underwent cardiac surgery. Computed tomography is essentially noninvasive and appears to be one of the best methods to evaluate left atrial thrombus.

Aged↗

Clinical application of cardiovascular computed tomography.

The application of computed tomography to cardiovascular diagnosis was attempted. One hundred and four consecutive patients with various cardiovascular diseases were studied with a third-generation computed tomographic three-second whole body scanner. Identification and evaluation of abnormalities of the great vessels, atria, ventricles and interventricular septum were possible by cardiac computed tomography. Sizes and locations of intracardiac thrombi were accurately assessed by computed tomography. Computed tomography was valuable for the evaluation of pericardial effusion because distribution of the effusion as well as the gross nature of the fluid could be estimated by the CT number.

Cardiovascular Diseases↗

A case of persistent atrial standstill.

A case of persistent atrial standstill is described. The criteria for diagnosing atrial standstill are separated into two categories: the lack of electrical atrial activity and the lack of mechanical atrial activity. Echocardiography of the anterior mitral leaflet is to be used as one of the noninvasive methods for the diagnosis of the lack of mechanical atrial activity.

Adolescent↗

Effect of nicotinic acid on catecholamine synthesis in rat brain.

Effect of nicotinic acid on the formation of catecholamine has been studied. Norepinephrine and dopamine concentrations in brain were 30 per cent higher and brain catecholamine formation was 50 per cent higher in the nicotinic acid-supplemented rats than the nicotinic acid-deficient rats. However, these catecholamine levels of the nicotinic acid-deficient rats were recovered by the administration of nicotinic acid. The concentration of brain tyrosine was unaltered after administration of nicotinic acid to the nicotinic acid-deficient rats. Therefore, the changes catecholamine formation by the nicotinic acid supplementation were not due to the difference of tyrosine concentration in the brain which is the precursor for catecholamine biosynthesis. As the difference of catecholamine concentration between the nicotinic acid deficient and the nicotinic acid supplemented group was smaller than that of catecholamine formation of these groups, the turnover of catecholamine was supposed to be decreased in nicotinic acid deficiency.

Animals↗