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Biomedical subjects

S Kaufman

Publications and source records attributed to S Kaufman.

At least 487 records · Page 27Linked to original sources
PubMed1967

Enhanced protein synthesis in a cell-free system from hypertrophied skeletal muscle.

Hypertrophy of the rat soleus muscle was induced by tenotomy of the synergistic muscles. Four days after the operation, the weight of the muscle had increased by 30 percent. The hypertrophied muscle had an increased concentration of DNA and RNA, when compared to the contralateral control soleus. Although the amount of myofibrillar protein increased during the 4-day period, the concentration of this component decreased. Microsomes prepared from hypertrophied muscle had an increased RNA concentration. The combined microsomes and pH-5 enzyme from hypertrophied muscle supported a faster rate of protein synthesis in vitro than the same system prepared from an equal weight of contralateral muscle which was used as a control.

Animals↗
PubMedDate not supplied

Accuracy of frozen-section diagnosis in salivary gland neoplasms.

A retrospective review of 100 patients with major or minor salivary gland neoplasms was conducted to ascertain the accuracy and effect on therapy of frozen-section diagnosis. Of these patients, 23% had malignant and 77% benign neoplasms. Twelve patients benefited by further surgery during the initial operation, and no treatment delay occurred as a result of frozen-section diagnosis. There were four incorrect diagnoses of clinical significance, two false positives (benign tumor called malignant on frozen section) and two false negatives (malignant tumor called benign on frozen section). The accuracy of frozen section for specific pathologic diagnosis was 92%. No unnecessary radical surgery was performed. Frozen-section diagnosis of salivary gland neoplasms in our institution was found to be accurate and useful.

Adenoma, Pleomorphic↗