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Biomedical subjects

S Kato

Publications and source records attributed to S Kato.

At least 1,351 records · Page 75Linked to original sources
PubMed1988

Establishment and characterization of three new human gestational choriocarcinoma cell lines.

Three gestational choriocarcinoma cell lines (NaUCC-1, -2, and -3) were established by transplanting tumors taken from three human choriocarcinoma patients to nude mice. Anti-nude mouse rabbit serum was used to eliminate the contamination by mouse interstitial cells. Microscopically, NaUCC-1 and -2 contained few endoplasmic reticula (ER) and many ribosomes, were rich in polysomes, and showed homogenous morphology, while NaUCC-3 contained many ER and lipid-like granules, and showed variations in size. In chromosome analysis, NaUCC-1, -2 and -3 were found to be mostly hypertetraploid, hyperdiploid and hypertriploid respectively. The in vitro doubling time was close in all three lines, ranging from 20 to 25 hours. Human chorionic gonadotropin (hCG) was produced in each cell line, with the largest amount being NaUCC-3. The supernatant of each cell line contained progesterone and estrogen but not human placental lactogen (hPL). Thus, these choriocarcinoma cell lines were found to differ a little from one another.

Adult↗
PubMed1988

[Clinical experiences of renal and ureteral stones by extracorporeal shock-wave lithotripsy (ESWL). IV: 3-year clinical experience of cases treated with ESWL].

We report our 3-year experience with extracorporeal shock wave lithotripsy (ESWL) since we first used it for upper urinary tract stones on September 1st, 1984. A total of 1,225 patients (1,320 cases) underwent 1,647 sessions with ESWL; They consisted of 855 males (70%) and 370 females (30%). Treated stone locations were 593 renal stones, which contained 112 complete staghorn calculi, 504 ureteral stones, 110 renoureteral stones, and 1 bladder stone. ESWL monotherapy was performed on 90% of cases with renal and ureteral stones, and 46% of cases with complete staghorn calculi. In all the cases so far observed for more than 12 weeks after ESWL, 84.9% of the former showed complete discharge of the stones, and 0.7% showed no change. Only 48.9% of the later showed the complete discharge of the stones, 43.3% of which had residual stones, and 7.8% had fragments of the size of small beans. Complications, which were fever and pain, were noticed in 33.6% of the cases with renal and ureteral stones, and 64.3% of the cases with complete staghorn calculi. After ESWL, hematuria was noticed in almost cases, but the average volume of hemorrhage was 28 +/- 33 ml/day. The only contraindication of ESWL was severe obesity, and in the cases in which spontaneous stone discharge can be expected.

Adolescent↗
PubMed1988

[Spontaneous cerebrospinal fluid fistula in association with congenital inner ear anomaly: a case report].

A case of inner ear anomaly (Mondini dysplasia) associated with recurrent meningitis found in a 10 year-old boy is reported. The patient had suffered from bacterial meningitis and CSF rhinorrhea five times in 7 years. The origin of CSF leakage had not been detected by bifrontal craniotomy or trans-sphenoidal operation. In May 1985, the dysplasia of the temporal bone and the inner ear had been pointed out by an otologist. And he underwent operations a few times for closing the CSF fistula at the floor of the internal auditory meatus by translabyrinthine approaches, but in vain. On the 7th of November 1985, under the control of intracranial pressure by continuous ventricular drainage, re-operation was performed. Packing the internal auditory meatus with several pieces of muscle and gelatine sponge stopped the CSF leakage and the recurrence of meningitis.

Cerebrospinal Fluid Otorrhea↗
PubMed1988

[Clinical statistics on outpatients at the Urological Clinic of Sanjukai Hospital in 1987].

The total number of new outpatients in 1987 was 8,062 (male 5,056, female: 3,006) and the male to female ratio was 1.68:1. They had urogenital diseases definitely diagnosed (7,197), urogenital diseases indefinitely diagnosed (536), no diseases (269), and diseases other than urogenital (60). Thirty percent of the outpatients were referred to us by other sources. The number of operations on new outpatients was 216, circumcision, resection of condyloma and vasectomy were representative. The peak of the age distribution was in the thirties for males and in the fifties for females. A statistical study was made on new outpatients according to the international classification of disease. There were 125 malignant (urogenital) tumors (1.6%). The major diseases of the new outpatients were cystitis (acute or chronic: 22.0%), upper urinary tract stone (15.9%), prostatitis (13.9%), and benign prostatic hypertrophy (11.9%). In males the major diseases were prostatitis, upper urinary tract stone, benign prostatic hypertrophy, balanoposthitis, phimosis and in females they were cystitis, upper urinary tract stone, pyelonephritis, renoptosis, and neurogenic bladder. We conclude that our hospital plays a major role as a private urological hospital.

Adolescent↗
PubMed1988

[A successful removal of huge confluence meningioma].

A rare case of huge confluence meningioma with many kinds of venous collaterals is presented. A 58-year-old female was admitted because of severe headache and gait disturbance. An enhanced CT (computerized tomography) scan demonstrated a homogeneous spherical high density mass in the region of the posterior falco-tentorial junction adjacent to the internal occipital crest. Cerebral angiograms showed (1) the occluded confluence sinuum and compensatory venous collaterals, (2) venous drainage through the persistent falcial sinus, which was rare in an adult, from the straight sinus into the superior sagittal sinus (SSS), (3) venous drainage through diploic veins and emissary veins into scalp veins. The tumor including the confluence sinuum was totally removed via a combined bioccipital and suboccipital craniectomy. The confluence sinuum was invaded and occluded by the tumor. The tumor was histologically diagnosed as a fibroblastic meningioma. Post-operative angiogram showed a formation of the new venous channel which is located between the posterior part of the SSS and the lateral part of right transverse sinus. The origin of this new venous pathway was thought to be congenital presence of a "latent" dural venous channel. After ventriculoperitoneal shunting, the patient was discharged without any neurological deficits. A follow-up angiogram one year and two months after discharge showed that the channel become dilated and the venous collaterals seen before surgery disappeared probably due to the change of balance of venous pressure. The venous drainage pattern seemed to become resembling the normal variant type in which the SSS drains into the right transverse sinus, and left sinus was hypoplastic.(ABSTRACT TRUNCATED AT 250 WORDS)

Cerebral Angiography↗
PubMed1988

[Clinical results of percutaneous nephroureterolithotripsy].

Thirty-five patients (37 renal units) were treated by PNL. Nine had complete staghorn calculi, 2 multiple reno-ureteral stones, 12 solitary renal stone, and 14 upper ureteral stone. The success rate was 94.6%. No severe complications were seen.

Adult↗
PubMed1988

[Clinical evaluation of long-term administration of terodiline hydrochloride for the treatment of patients with pollakisuria and incontinence].

We evaluated the effectiveness and side effects of long-term administration of terodiline hydrochloride in patients with chief complaints of pollakisuria or incontinence or both due to unstable bladder or neurogenic bladder associated with uninhibited contraction. The dose was 24 mg once daily. The symptoms such as pollakisuria and incontinence improved in 31 out of 41 patients (76%). Mild side effects were observed in 12 out of 47 patients (26%), which were thirst, dizziness, dysuria, urticaria and gastrointestinal symptoms. An increasing tendency of both maximum desire to void and compliance (p less than 0.10), and significant difference in maximum static pressure (p less than 0.05) were observed on urodynamic examinations before and after administration of this medicine. The results obtained from this study suggest that terodiline hydrochloride may be greatly recommended for patients with such symptoms as pollakisuria and incontinence.

Adult↗