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Biomedical subjects

S Kasperek

Publications and source records attributed to S Kasperek.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

[Retinal changes in subacute sclerosing panencephalitis].

In a 12-year-old boy with histologically confirmed subacute sclerosing panencephalitis changes resembling chorioretinitis were found in the peripheral part of the left retina. Fluorescein angiography demonstrated signs of atrophy of pigmented epithelium. On the basis of pertinent literature the authors suggest that in this disease retinal involvement may precede neurological manifestations. It would be interesting to try whether therapy applied in this early stage would be effective.

Antibodies↗
PubMedDate not supplied

[Subacute sclerosing panencephalitis pregnancy].

In a patient aged 16 behaviour at changes, followed by visual agnosia, aphasia, paraparesis and involuntary movements developed about the 24th week of pregnancy. The presence of measles virus antibodies in the cerebrospinal fluid and progressing course of the disease with fever suggested SSPE. Pregnancy was terminated by caesarean section in the 30th week of pregnancy, the male premature baby died after 4 days, his brain was not examined under microscope. The mother died 2 weeks after labour in decerebrate rigidity. In the brain numerous profuse infiltrations composed of lymphocytes and plasma cells were found around blood vessels, the glia was proliferated and hypertrophied, eosinophilic inclusions were demonstrated in the nucleic of cortical neurons. The authors review the very few case, reported as yet, of SSPE in pregnant women. During pregnancy natural immunosuppression occurs, which may lead to activation of dormant infection with measles virus mutant. However, the history of one of the published cases suggests the possibility of other pathogenetic factors active in such cases.

Adolescent↗
PubMedDate not supplied

[Brain lesions after radiotherapy].

On the basis of literature reports up to 1988 the incidence, clinical pattern and treatment of cerebral complications following radiotherapy administered to the organs and tissues of the head are discussed. Acute radiation-induced reaction and early delayed reaction in the form of e.g. the so called somnolence syndrome or rhombencephalopathy are rare and their prognosis is usually good. In 1 to 14% of the patients delayed reaction may develop corresponding to the late radiation necrosis, usually with progressive unfavourable course. A problem of practical importance is the impossibility of differentiating radiation-induced cerebral necrosis from recurrence, expansion of the primary tumour or metastatic tumour, even using CT and MNR. Only the poorly available positron emission tomography makes possible differential diagnosis. Sometimes, surgical or pharmacological treatment of cerebral necrosis is effective.

Brain↗
PubMedDate not supplied

[Course of cerebral cysticercosis].

In the light of 4 cases of cerebral cysticercosis observed in the period 1970-1976 in Zabrze the authors call attention to the possibility of a very long, lasting even tens of years, time period preceding development of intracranial hypertension and to the diagnostic difficulties in this period. If immunological reactions are negative and the cerebrospinal fluid is normal, presence of calcified cysts in skeletal muscles visible on radiograms may be helpful. An uncertain syndrome of cerebral manifestations in a patient with occupational exposure (butchers) requires ruling out of cysticercosis. Three of these patients were butchers. In 2 plain radiograms showed calcified cysticerci in the muscles, in one they were present in the brain.

Adult↗
PubMedDate not supplied

[Ataxic form of Jakob-Creutzfeldt syndrome].

The authors describe a man aged 43 years with a typical onset of the disease with cerebellar signs and progressive dementia prevailing during a 4 month course of the illness. Neuropathological examination demonstrated subacute spongiform encephalopathy with significant although not overwhelming damage to the cerebellar cortex. The case is an example of the ataxic form of this disease isolated in 1965. In the clinical diagnosis of Creutzfeldt-Jakob disease cerebellar signs may play a similarly important role as myoclonia and characteristic EEG curve.

Adult↗
PubMedDate not supplied

[Statistical analysis of mortality from stroke in hospitalized patients].

The authors analysed mortality from brain strokes in 1366 patients hospitalized at the Department of Neurology, Silesian Medical Academy in Katowice and Zabrze and in the 8th Municipal Hospital in Katowice in the years 1970--1974. The number of cases with lethal outcome was 437. The mortality was highest in cases of cerebral haemorrhages, particularly in women. The mortality increased with increasing age and was highest in the first 24 hours of treatment.

Cerebral Hemorrhage↗
PubMedDate not supplied

[Isolated temporary pharyngeal paralysis in childhood. Viral neuroinfection with a mild course?].

The authors describe a boy aged 14 years who had identical signs as those described in 1976 in cases of isolated temporary pharyngeal paralysis (Edin et al). In this syndrome Sullivan and Carlson (1976) observed a rise in the titre of antibodies to Herpes simplex virus, and Nussey (1977) found in it infection caused by Coxsackie type A9 virus. In the presently reported case full serological and virological investigations were not done.

Adolescent↗
PubMedDate not supplied

[Neurocysticercosis: benign natural course].

In a waiter aged 51 without clinical symptoms, but with a history of sporadic epileptic seizures in young age, radiological examination demonstrated multiple calcifications in the brain corresponding to calcified cysticerci. Similar lesions were found in the muscles of the thighs and left lower leg. After another 18 years without cerebral symptoms these calcifications were demonstrated in CT. The case indicates that the natural course of cerebral cysticercosis may be asymptomatic or oligosymptomatic, and that it is useful to distinguish between active and inactive cysticercosis.

Animals↗
PubMedDate not supplied

[Intramedullary metastasis of pulmonary carcinoma].

An autopsied case of intramedullary metastasis of microcellular pulmonary carcinoma is described. Data of the incidence and clinical course of intramedullary metastases are presented.

Carcinoma, Medullary↗
PubMedDate not supplied

[Thoracic radiation myelopathy].

In a 62-year-old patient 8 month after radiotherapy for right pulmonary hilus carcinoma signs of thoracis cord involvement with ascending course from Th10 to Th7. Cerebrospinal fluid and myelogram were normal. The patient died after about 12 months. Radiation myelopathy was confirmed by neurohistological examination. The results of experimental studies are quoted which could predict the possibility of early diagnosis of radiation myelopathy by rising level of basic myelin protein in cerebrospinal fluid.

Carcinoma↗