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S Karlsen

Publications and source records attributed to S Karlsen.

6 recordsLinked to original sources

Branched renal calculi treated by percutaneous nephrolithotomy and extracorporeal shock waves.

Fifty-four renal staghorn calculi, 26 complete and 28 partial, were treated in 51 patients by percutaneous nephrolithotomy (PCN) in combination with extracorporeal shock wave lithotripsy (ESWL) when necessary. At an average time of observation of 11.1 months, 56% of the renal units were stone free. Twenty-two per cent had residual gravel of less than 2 mm in diameter and 15% contained residuals between 2 and 5 mm in diameter. Seven per cent of the kidneys had significant residual calculi. Additional endourological procedures were required in 13 cases. Complications were minimal and were all conservatively treated. PCN in combination with ESWL is an effective treatment of most branched renal calculi. The methods may be used repeatedly without increasing technical difficulty. The results compare well with open surgery.

Female

High-dose medroxyprogesterone acetate versus prednisolone in hormone-resistant prostatic cancer. A pilot study.

Medroxyprogesterone acetate (MPA) (1,000 mg daily per os) yielded (mainly subjective) remissions in 8 of 21 patients with hormone-resistant cancer of the prostate. In 24 comparable patients, treated with prednisolone (20 mg daily per os) 3 remissions were observed, indicating a slight superiority of high-dose MPA considering the response rate. The response duration for both drugs was relatively short (2-7 months). No survival benefit for either drug was observed. In patients with hormone-resistant cancer of the prostate, a significant improvement of the performance status should be registrated as subjective response. This is a major aim of any treatment in these patients. Normalization of serum acid phosphatase may also be considered as remission. The type of remission (greater than 50% reduction of measurable tumor lesions, reduction of serum acid phosphatase, subjective remission) should always be indicated in the individual report dealing with phase II/phase III studies in patients with hormone-resistant prostatic cancer.

Acid Phosphatase

[Hematospermia].

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Adult

Intraluminal duodenal diverticulum. Report of a case diagnosed by endoscopy.

Intraluminal diverticulum of the duodenum is a very rare congenital anomaly arising in the second part of the duodenum in close relation to the papilla of Vater. 39 cases have been reported in our available literature. The clinical symptoms and signs are nonspecific, and characteristically the preoperative diagnosis has in all cases been based on the roentgenographic appearance of the lesion. In this paper we present a case diagnosed by duodenoscopy, the radiological studies including hypotonic duodenography revealing no pathology.

Adult