[Maternofetal complications caused by amniocentesis].
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Biomedical subjects
Publications and source records attributed to S Karchmer.
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Serum prolactin (PRL) was measured by radioimmunoassay in 80 women in serum and amniotic fluid during various stages of normal pregnancy and at delivery. In addition, prolactin levels were measured in cord sera at 60 newborns. PRL levels in maternal serum progressively increased during pregnancy, and they were lower than the corresponding levels in amniotic fluid. A relative decline in the amniotic fluid prolactin between the 39th and the 40th week of gestation was observed. The mean concentration of PRL in umbilical blood was significant lower than that in maternal blood at delivery. The lack of correlation between the PRL in amniotic fluid and the levels found in maternal and newborns serum suggests an independient source of PRL in each of the three compartments.
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Anterior pituitary responsiveness to parturition was studied in 28 normal newborn infants. Cord blood sera samples were obtained for measurement of TSH, HGH, PRL, and FSH at birth and at intervals during four hours. The neonate infant's pituitary response to parturition consists of both PRL and TSH increments, which is probably mediated by an increase in TRH release.
The sociocultural, psychological, and medical effects of maternal death are described and analyzed for the purpose of appraising the value of the given death as a measure of the quality of medical care. The work of the Maternal Mortality Committee of the Hospital de Gineco-Obstetetricia No. 1 of the Mexican Social Security Institute over its three years of operation and some results on responsiblity for death and its possible predictabilty are presented. The results show that it is necessary to broaden the Committee's functions in a social, professional, and institutional context so that the indicated factors may be objectively assessed and also that the Committee be transformed into a dynamic organism that will contribute to solving the problem. Recommendations for the operation of the Maternal Mortality Committees are given.
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External fetal electrocardiography was performed in three groups of normal pregnant patients delivered of normal newborn infants. Maternal and fetal heart rates were compared and maternal heart rates in the three trimesters were analyzed. Mean heart rates, as well as standard deviations of the three groups, were compared in mother and fetus. The results confirm previous work establishing the independence of fetal and maternal heart rates in the absence of maternal hemodynamic changes mediated by various factors.
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